Results 41 to 50 of about 4,471,992 (283)

Modelling the effect of vascular status on tumour evolution and outcome after thermal therapy [PDF]

open access: yesarXiv, 2022
Microscale oxygenation plays a prominent role in tumour progression. Spatiotemporal variability of oxygen distribution in the tumour microenvironment contributes to cellular heterogeneity and to the emergence of normoxic and hypoxic populations.
arxiv  

Development of the Human Placenta and Fetal Heart: Synergic or Independent?

open access: yesFrontiers in Physiology, 2018
The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical circulation receives at least 40% of the biventricular cardiac output.
Graham J. Burton, Eric Jauniaux
doaj   +1 more source

Resistance Mechanisms to Anti-angiogenic Therapies in Cancer

open access: yesFrontiers in Oncology, 2020
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth factor signaling, endothelial cell (EC) proliferation, extracellular matrix (ECM ...
Y. Haibe   +6 more
semanticscholar   +1 more source

Effect of propofol on cerebral blood flow in patients with severe traumatic brain injury undergoing decompression craniectomy

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To analyze the effect of propofol on cerebral blood flow (CBF) in patients with severe traumatic brain injury (sTBI). Methods A total of 60 patients of sTBI undergoing unilateral decompression craniectomy in the Department of Neurosurgery from ...
Shao⁃bo REN, Li⁃hong LI
doaj  

Increased Serum Klotho With Age-Related Aortic Stiffness and Peripheral Vascular Resistance in Young and Middle-Aged Swine

open access: yesFrontiers in Physiology, 2020
The anti-aging function of Klotho gene has been implicated in age-related diseases. The physiological importance of Klotho in the progression of arterial stiffness with aging, however, remains unclear.
Xiaomei Guo, Ghassan S. Kassab
doaj   +1 more source

METOCLOPRAMIDE AND RENAL VASCULAR RESISTANCE

open access: yesBritish Journal of Anaesthesia, 1991
We have studied the effect of i.v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived.
C.R. Monk   +4 more
openaire   +3 more sources

Central and peripheral pathogenetic forms of type 2 diabetes: a proof-of-concept study

open access: yesEndocrine Connections, 2016
Hypothesis Previous studies provide evidence that glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG) should not be considered as interchangeable alternatives in the diagnosis of the same type 2 diabetes, but as indicators of its different ...
Dmitry M Davydov, Malik K Nurbekov
doaj   +1 more source

Single-Cell RNA Sequencing Revealed CD14+ Monocytes Increased in Patients With Takayasu’s Arteritis Requiring Surgical Management

open access: yesFrontiers in Cell and Developmental Biology, 2021
Objectives: Takayasu Arteritis (TA) is a highly specific vascular inflammation and poses threat to patients’ health. Although some patients have accepted medical treatment, their culprit lesions require surgical management (TARSM).
Gao Qing   +18 more
doaj   +1 more source

Vascular smooth muscle contraction in hypertension

open access: yesCardiovascular Research, 2018
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease.
R. Touyz   +6 more
semanticscholar   +1 more source

Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries [PDF]

open access: yesPLoS ONE 11(10):e0165369 (2016), 2016
During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous and capillary surfaces, reconstructed from confocal laser scanning microscopy, to finite-element meshes ...
arxiv   +1 more source

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