Results 41 to 50 of about 5,118,564 (403)
Cardiovascular Diabetology, 2016 BackgroundHigh fat diet (HFD) induces insulin resistance in various tissues, including the vasculature. HFD also increases plasma levels of TNF-α, a cytokine that contributes to insulin resistance and vascular dysfunction.
Rafael M. da Costa +5 more
semanticscholar +1 more source
Vascular Microenvironment, Tumor Immunity and Immunotherapy
Frontiers in Immunology, 2021 Immunotherapy holds great promise for treating cancer. Nonetheless, T cell-based immunotherapy of solid tumors has remained challenging, largely due to the lack of universal tumor-specific antigens and an immunosuppressive tumor microenvironment (TME ...
Zachary L Lamplugh, Yi Fan
semanticscholar +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2011 Introducción. Existen pocos datos con respecto a los efectos de la carbamacepina y sus derivados en el aparato cardiovascular; además, el mecanismo molecular y su sitio de acción celular no son claros. Objetivo.
Lauro Figueroa-Valverde +4 more
doaj +1 more source
Environmental Health Perspectives, 2016 Background: Epidemiological evidence suggests that exposure to ambient air fine particulate matter (PM2.5) increases the risk of developing type 2 diabetes and cardiovascular disease.
semanticscholar +1 more source
Riociguat for the treatment of chronic thromboembolic pulmonary hypertension. [PDF]
, 2013 BACKGROUND: Riociguat, a member of a new class of compounds (soluble guanylate cyclase stimulators), has been shown in previous clinical studies to be beneficial in the treatment of chronic thromboembolic pulmonary hypertension. METHODS: In this phase 3,
CHEST-1 Study Group, +13 more
core +1 more source
Changes in Vascularization of Human Breast Cancer Xenografts Responding to Antiestrogen Therapy
Neoplasia: An International Journal for Oncology Research, 1999 To elucidate the previously suggested vascular effect(s) of antiestrogen therapy, we studied the effect of estrogen withdrawal and tamoxifen on 1) vascular resistance, 2) glucose and oxygen consumption, 3) vascular density in a perfused breast cancer ...
Claus A. Kristensen +6 more
doaj +1 more source
Carotid baroreceptor reflexes in humans during orthostatic stress [PDF]
, 2001 Orthostatic stress, including standing, head-up tilting and lower body suction, results in increases in peripheral vascular resistance but little or no change in mean arterial pressure.
Cooper, V.L., Hainsworth, R.
core +1 more source
Effect of Angiotensin II on Blood Flow in Acute and Chronically Inflamed Knee Joints of Rabbits: The Role of Nitric Oxide [PDF]
Iranian Journal of Medical Sciences, 2009 Background: Angiotensin converting enzyme (ACE) upregulationin stromal cells of joints affected by rheumatoid arthritismay lead to higher tissue angiotensin II that is a vasoconstrictorand mitogen factor.
Hamid Najafipour +3 more
doaj
Descending Aorta Blood Flow Characteristics before the Development of Necrotizing Enterocolitis in Preterm Neonates [PDF]
Neonatal Medicine, 2018 Purpose To investigate the hemodynamic risk factors for necrotizing enterocolitis (NEC), we analyzed the characteristics of descending aorta (DA) blood flow in preterm neonates, who later developed NEC.
Kyung Min Kim +9 more
doaj +1 more source
The response of tumour vasculature to angiotensin II revealed by its systemic and local administration to 'tissue-isolated' tumours [PDF]
, 1995 A tissue-isolated preparation of the P22 rat carcinosarcoma was used to investigate the tumour vascular response to angiotensin II (ATII). In particular, the relative importance of systemic and local tumour factors was assessed by comparing tumour ...
Tozer, G.M., Shaffi, K.M.
core +1 more source