Results 41 to 50 of about 4,471,992 (283)
Modelling the effect of vascular status on tumour evolution and outcome after thermal therapy [PDF]
Microscale oxygenation plays a prominent role in tumour progression. Spatiotemporal variability of oxygen distribution in the tumour microenvironment contributes to cellular heterogeneity and to the emergence of normoxic and hypoxic populations.
arxiv
Development of the Human Placenta and Fetal Heart: Synergic or Independent?
The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical circulation receives at least 40% of the biventricular cardiac output.
Graham J. Burton, Eric Jauniaux
doaj +1 more source
Resistance Mechanisms to Anti-angiogenic Therapies in Cancer
Tumor growth and metastasis rely on tumor vascular network for the adequate supply of oxygen and nutrients. Tumor angiogenesis relies on a highly complex program of growth factor signaling, endothelial cell (EC) proliferation, extracellular matrix (ECM ...
Y. Haibe+6 more
semanticscholar +1 more source
Objective To analyze the effect of propofol on cerebral blood flow (CBF) in patients with severe traumatic brain injury (sTBI). Methods A total of 60 patients of sTBI undergoing unilateral decompression craniectomy in the Department of Neurosurgery from ...
Shao⁃bo REN, Li⁃hong LI
doaj
The anti-aging function of Klotho gene has been implicated in age-related diseases. The physiological importance of Klotho in the progression of arterial stiffness with aging, however, remains unclear.
Xiaomei Guo, Ghassan S. Kassab
doaj +1 more source
METOCLOPRAMIDE AND RENAL VASCULAR RESISTANCE
We have studied the effect of i.v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived.
C.R. Monk+4 more
openaire +3 more sources
Central and peripheral pathogenetic forms of type 2 diabetes: a proof-of-concept study
Hypothesis Previous studies provide evidence that glycated haemoglobin (HbA1c) and fasting plasma glucose (FPG) should not be considered as interchangeable alternatives in the diagnosis of the same type 2 diabetes, but as indicators of its different ...
Dmitry M Davydov, Malik K Nurbekov
doaj +1 more source
Objectives: Takayasu Arteritis (TA) is a highly specific vascular inflammation and poses threat to patients’ health. Although some patients have accepted medical treatment, their culprit lesions require surgical management (TARSM).
Gao Qing+18 more
doaj +1 more source
Vascular smooth muscle contraction in hypertension
Hypertension is a major risk factor for many common chronic diseases, such as heart failure, myocardial infarction, stroke, vascular dementia, and chronic kidney disease.
R. Touyz+6 more
semanticscholar +1 more source
Image-Based Modeling of Blood Flow and Oxygen Transfer in Feto-Placental Capillaries [PDF]
During pregnancy, oxygen diffuses from maternal to fetal blood through villous trees in the placenta. In this paper, we simulate blood flow and oxygen transfer in feto-placental capillaries by converting three-dimensional representations of villous and capillary surfaces, reconstructed from confocal laser scanning microscopy, to finite-element meshes ...
arxiv +1 more source