Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]
, 2012 During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE +6 more
core +1 more source
Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
, 2014 Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
core +8 more sources
Frontiers in Physiology, 2017 There are two primary components that produce pulmonary arterial hypertension (PAH); aberrant structural changes (smooth muscle cell proliferation, smooth muscle cell hypertrophy, and the deposition of matrix proteins within the media of pulmonary ...
Melissa A. Lyle +2 more
doaj +1 more source
Doppler sonography of the uterine and the cubital arteries in normal pregnancies, preeclampsia and intrauterine growth restriction: evidence for a systemic vessel involvement [PDF]
, 2006 Aims: The decrease in uterine resistance during normal pregnancy is known to be related to invading trophoblast cells which derive from placental tissue. Uterine and peripheral resistance is elevated in preeclampsia.
Friese, Klaus +4 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2021 Objectives: Takayasu Arteritis (TA) is a highly specific vascular inflammation and poses threat to patients’ health. Although some patients have accepted medical treatment, their culprit lesions require surgical management (TARSM).
Gao Qing +18 more
doaj +1 more source
Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]
, 2018 Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J. +2 more
core +1 more source
Changes in central and peripheral hemodynamic parameters during blood donation
Frontiers in Cardiovascular MedicineBackgroundBlood donation is a common procedure, yet its acute effects on central and peripheral hemodynamics are not fully understood. This study aimed to systematically quantify immediate cardiovascular changes induced by whole blood donation in healthy
Babak Yazdani +13 more
doaj +1 more source
Development of the Human Placenta and Fetal Heart: Synergic or Independent?
Frontiers in Physiology, 2018 The placenta is the largest fetal organ, and toward the end of pregnancy the umbilical circulation receives at least 40% of the biventricular cardiac output.
Graham J. Burton, Eric Jauniaux
doaj +1 more source
Comparison of Carotid Artery Intima-media Thickness and Resistive Index by Ultrasound and Colour Doppler in Pre-hypertensives and Stage One Hypertensives [PDF]
International Journal of Anatomy Radiology and Surgery, 2019 Introduction: Pre-hypertension and stage one hypertension remains major public health problem in both developed and developing countries. It primarily affects elastic arteries, hence common carotid artery Intima-Media Thickness (IMT) and Resistive ...
Subha Venkatachalam +5 more
doaj +1 more source
Cells, 2021 Background: Cardiovascular dysfunction is linked to insulin-resistant states. In this paper, we analyzed whether the severe hepatic insulin resistance of an inducible liver-specific insulin receptor knockout (iLIRKO) might generate vascular insulin ...
Almudena Gómez-Hernández +9 more
doaj +1 more source