Results 131 to 140 of about 769,970 (260)

Somatic PDGFRB activating variants promote smooth muscle cell phenotype modulation in intracranial fusiform aneurysm

open access: yesJournal of Biomedical Science
Background The fusiform aneurysm is a nonsaccular dilatation affecting the entire vessel wall over a short distance. Although PDGFRB somatic variants have been identified in fusiform intracranial aneurysms, the molecular and cellular mechanisms driving ...
Li Hao   +12 more
doaj   +1 more source

Automated 1D Helmholtz coil design for cell biology: Weak magnetic fields alter cytoskeleton dynamics [PDF]

open access: yesarXiv
For more than fifty years, scientists have been gathering evidence of the biological impacts of weak magnetic fields. However, the lack of systematics in experimental studies has hampered research progress on this subject. To systematically quantify magnetic field effects in cell biology, it is crucial to produce fields that can be automatically ...
arxiv  

Laplacian Flow Dynamics on Geometric Graphs for Anatomical Modeling of Cerebrovascular Networks [PDF]

open access: yesarXiv, 2019
Generating computational anatomical models of cerebrovascular networks is vital for improving clinical practice and understanding brain oxygen transport. This is achieved by extracting graph-based representations based on pre-mapping of vascular structures.
arxiv  

The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]

open access: yes, 2008
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek   +5 more
core   +1 more source

Disruption of the Sarcoglycan–Sarcospan Complex in Vascular Smooth Muscle A Novel Mechanism for Cardiomyopathy and Muscular Dystrophy [PDF]

open access: yes
To investigate mechanisms in the pathogenesis of cardiomyopathy associated with mutations of the dystrophin–glycoprotein complex, we analyzed genetically engineered mice deficient for either α-sarcoglycan (Sgca) or δ-sarcoglycan (Sgcd).
Bansal, Dimple   +11 more
core   +1 more source

Cell Autonomous and Non-cell Autonomous Regulation of SMC Progenitors in Pulmonary Hypertension

open access: yesCell Reports, 2018
Summary: Pulmonary hypertension is a devastating disease characterized by excessive vascular muscularization. We previously demonstrated primed platelet-derived growth factor receptor β+ (PDGFR-β+)/smooth muscle cell (SMC) marker+ progenitors at the ...
Abdul Q. Sheikh   +4 more
doaj  

Functional preservation of vascular smooth muscle tissue [PDF]

open access: yes
The ionic and cellular feedback relationships operating to effect the vascular decompensatory modifications were examined to reveal procedures for implementing protective measures guarding against vascular collapse when returning from a weightless ...
Alexander, W. C.   +2 more
core   +1 more source

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