Results 201 to 210 of about 708,976 (400)

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, Volume 12, Issue 28, July 24, 2025.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

Advanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang, Ye Zhang, Zhu Liu, Zhiyuan Wang, Huaqin Wang, Xiaoyu Ji, Hongyue Su, Fan Yang, Lirong Yan, Ying Xu, Hao Zhang, Wei Sun   +11 more
wiley   +1 more source

Calcium leakage as a cause of the high resting tension in vascular smooth muscle from the spontaneously hypertensive rat.

, 1978
Joseph P. Noon, Peter J. Rice, Ross J. Baldessarini   +2 more
openalex   +1 more source

Human Bone‐Derived Endothelial Cells Mediate Bone Regeneration via Distinct Expression of KIT Ligand

Advanced Science, EarlyView.
Bone‐specific endothelial cells (b‐ECs) uniquely express KITLG, which recruits c‐Kit+/CD34+ hematopoietic progenitors (HPCs) to the osteovascular niche, initiating a cascade that culminates in the osteogenic differentiation of bone marrow‐derived mesenchymal stem cells (bm‐MSCs) and subsequent ossification.
Xiang Li, Hwan D. Kim, Allen C. Luo, Liyan Gong, Yonglin Zhu, Chin Nien Lee, Xuechong Hong, Christopher L. Sudduth, Michal Ad, Young‐Hyeon An, Mihn Jeong Park, Do‐Gyoon Kim, Arin K. Greene, Bonnie L. Padwa, Nathaniel S. Hwang, Ruei‐Zeng Lin, Juan M. Melero‐Martin   +16 more
wiley   +1 more source

Vascular Smooth Muscle Cells: A Therapeutic Target in Atherosclerosis. [PDF]

Rev Cardiovasc Med
Zhao L, Zhao L, Liu D, Huang F, Peng Q, Lu J, Zhou J, Zheng S, Liu X.   +8 more
europepmc   +1 more source

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source

The Pathophysiological Role of Vascular Smooth Muscle Cells in Abdominal Aortic Aneurysm. [PDF]

Cells
Shi D, Zhang M, Zhang Y, Shi Y, Liu X, Wu X, Yang Z.   +6 more
europepmc   +1 more source

RELEVANCE OF VASCULAR STRUCTURAL AND SMOOTH MUSCLE SENSITIVITY CHANGES IN HYPERTENSION [PDF]

, 1976
David F. Bohr, Kathleen H. Berecek
openalex  

Regulation of the cell magnesium in vascular smooth muscle

, 1974
Vladimír Palatý
openalex   +2 more sources

Regulation of voltage‐gated potassium channels in vascular smooth muscle during hypertension and metabolic disorders

Microcirculation, 2018
Madeline Nieves-Cintrón, A. Syed, Matthew A. Nystoriak, Manuel F. Navedo   +3 more
semanticscholar   +1 more source