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Mechanics of Vascular Smooth Muscle
Comprehensive Physiology, 2016ABSTRACTVascular smooth muscle (VSM; see Table 1 for a list of abbreviations) is a heterogeneous biomaterial comprised of cells and extracellular matrix. By surrounding tubes of endothelial cells, VSM forms a regulated network, the vasculature, through which oxygenated blood supplies specialized organs, permitting the development of large multicellular
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Leptin and Vascular Smooth Muscle Cells
Current Pharmaceutical Design, 2014This review concerns the influence of leptin on vascular smooth muscle cells (VSMC). VSMC express different isoforms of the leptin receptor (Ob-R) able to activate a wide range of intracellular signalling pathways, mediating many relevant biological actions.
TROVATI, Mariella +5 more
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Vascular smooth muscle and arterial calcification
Zeitschrift f�r Kardiologie, 2000Smooth muscle cultures can calcify under certain circumstances. As a model system these cultures therefore provide information on why calcification occurs in atherosclerotic plaques. Whether all smooth muscle cells (under certain conditions), or only specific populations, can produce this mineralization has not been resolved.
Campbell, G. R., Campbell, J. H.
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Calcium Kinetics in Vascular Smooth Muscle
Chest, 1985The accumulation, binding, and mobilization of Ca++ in vascular smooth muscle directly affects intracellular free Ca++ levels and contractility. Techniques have been developed to delineate Ca++ uptake and efflux parameters in isolated vessels. Similar Ca++-related components are present in different types of vessels, but their relative importance for ...
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1996
Smooth Muscle Tissue. The visceral mesenchyma (splanchnopleura) is the principal source for smooth muscle tissue. It also forms the layer-shaped muscle and connective tissue strata of the vessel walls. The vascular system of the human embryo develops from blood islets in the middle of the third week, shortly before somite formation, when the embryo can
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Smooth Muscle Tissue. The visceral mesenchyma (splanchnopleura) is the principal source for smooth muscle tissue. It also forms the layer-shaped muscle and connective tissue strata of the vessel walls. The vascular system of the human embryo develops from blood islets in the middle of the third week, shortly before somite formation, when the embryo can
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Melatonin Modulates Vascular Smooth Muscle Tone
Journal of Biological Rhythms, 1997The molecular cloning of a family of melatonin receptors has created a renewed interest in the diverse actions of the hormone melatonin. The redioligand 2-[125I]iodomelatonin has identified potential sites of action for melatonin throughout the central nervous system and periphery of numerous species.
C D, Mahle +4 more
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Oxygen sensors in vascular smooth muscle
Journal of Applied Physiology, 1994Inhibition or activation of cellular function due to acute decreases in PO2 can be considered in terms of two different processes: 1) a sensor that monitors PO2 decreases and 2) transduction systems directed from the O2 sensor to reactions that control cellular function.
Y, Katayama +3 more
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2002
Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
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Smooth muscle is present in one form or another in most organs, and its contractile activity is vital for normal functioning of the body. To be able to perform the multitude of tasks required of the organs, smooth muscle cells vary widely in their patterns of activity.
Campbell, G. R. +2 more
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Alkaline Phosphatase in Vascular Smooth Muscle
Nature New Biology, 1973THE free calcium ion is the essential common requirement for all muscle contraction including that of the vascular smooth muscle1,2. Tension development by the contractile proteins is a direct function of the Ca2+ concentration to which they are exposed.
C J, Limas, J N, Cohn
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MicroRNA and Vascular Smooth Muscle Cells
2011Vascular smooth muscle cells (VSMCs) exhibit extraordinary plasticity during postnatal development. Vascular injury initiates VSMC phenotypic switch from the contractile to proliferative phenotype, which plays a central role in vascular lesion formation and diverse vascular diseases.
Changqing, Xie +2 more
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