Results 31 to 40 of about 769,970 (260)
Journal of Extracellular Vesicles, 2020 The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer +7 more
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A model for the generation of localized transient Na+ elevations in vascular smooth muscle [PDF]
Biochem Biophys Res Commun 389, 461-465 (2009), 2009 We present a stochastic computational model to study the mechanism of signalling between a source and a target ionic transporter, both localized on the plasma membrane (PM) and in intracellular nanometre-scale subplasmalemmal signalling compartments comprising the PM, the sarcoplasmic reticulum (SR), Ca2+ and Na+ transporters, and the intervening ...
arxiv +1 more source
Role of endothelium in responses of vascular smooth muscle.
Circulation Research, 1983 Robert F. Furchgott
openalex +2 more sources
Arteriosclerosis, Thrombosis and Vascular Biology, 2019 Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood vessel degenerates, leading to dilation and eventually vessel wall rupture.
Ploingarm Petsophonsakul +9 more
semanticscholar +1 more source
Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]
, 2013 <p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo +47 more
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Smooth muscle cells largely develop independently of functional hemogenic endothelium
Stem Cell Research, 2014 Vascular smooth muscle cells represent a major component of the cardiovascular system. In vitro studies have shown that FLK1+ cells derived from embryonic stem (ES) cells can differentiate into both endothelial and smooth muscle cells.
Monika Stefanska +4 more
doaj +1 more source
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.
Circulation Research, 1994 The signaling pathways involved in the long-term metabolic effects of angiotensin II (Ang II) in vascular smooth muscle cells are incompletely understood but include the generation of molecules likely to affect oxidase activity.
K. Griendling +3 more
semanticscholar +1 more source
PLoS ONE, 2014 Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang +8 more
doaj +1 more source
Vascular Smooth Muscle Cells and Arterial Stiffening: Relevance in Development, Aging, and Disease.
Physiological Reviews, 2017 The cushioning function of large arteries encompasses distension during systole and recoil during diastole which transforms pulsatile flow into a steady flow in the microcirculation.
P. Lacolley +3 more
semanticscholar +1 more source
Close relation of arterial ICC-like cells to the contractile phenotype of vascular smooth muscle cell [PDF]
, 2007 This work aimed to establish the lineage of cells similar to the interstitial cells of Cajal (ICC), the arterial ICC-like (AIL) cells, which have recently been described in resistance arteries, and to study their location in the artery wall.
Bolton, TB +5 more
core +3 more sources