Results 31 to 40 of about 708,976 (400)

Human tribbles-1 controls proliferation and chemotaxis of smooth muscle cells via MAPK signaling pathways [PDF]

open access: yes, 2007
Migration and proliferation of smooth muscle cells are key to a number of physiological and pathological processes, including wound healing and the narrowing of the vessel wall.Previous work has shown links between inflammatory stimuli and vascular ...
Agnes Czibula   +58 more
core   +1 more source

Role of smooth muscle progenitor cells in vascular mechanical injury and repair

open access: yesMedicine in Novel Technology and Devices, 2022
Smooth muscle progenitor cells are precursor cells that express both smooth muscle cell and stem cell markers, and can differentiate into smooth muscle cells under specific condition.
Zhu-feng Dong   +7 more
doaj  

Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness

open access: yesCardiovascular Research, 2018
Vascular calcification is associated with a significant increase in all-cause mortality and atherosclerotic plaque rupture. Calcification has been determined to be an active process driven in part by vascular smooth muscle cell (VSMC ...
A. Durham   +4 more
semanticscholar   +1 more source

Calcium and Vascular Smooth Muscle Contraction [PDF]

open access: yesCirculation Research, 1971
Radioactive calcium flux in rabbit aorta was studied to evaluate factors regulating the movement of calcium into and out of the cell. Calcium content was estimated both from (1) the amount of 45 Ca present in the tissue and the specific activity of Ca in the bathing medium, and (2) determination of chemical calcium ...
Charles L. Seidel, David F. Bohr
openaire   +3 more sources

Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury [PDF]

open access: yes, 2014
Background The origins of neointimal smooth muscle cells that arise following vascular injury remains controversial. Studies have suggested that these cells may arise from previously differentiated medial vascular smooth muscle cells, resident stem ...
Burlak, Christopher   +3 more
core   +2 more sources

Assessment of a novel, capsid-modified adenovirus with an improved vascular gene transfer profile [PDF]

open access: yes, 2013
<p>Background: Cardiovascular disorders, including coronary artery bypass graft failure and in-stent restenosis remain significant opportunities for the advancement of novel therapeutics that target neointimal hyperplasia, a characteristic of both ...
AA Soyombo   +47 more
core   +2 more sources

Redox signaling, Nox5 and vascular remodeling in hypertension [PDF]

open access: yes, 2015
Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational ...
De Lucca Camargo, Livia   +5 more
core   +1 more source

Mebendazole reduces vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice.

open access: yesPLoS ONE, 2014
Mebendazole is an antihelminthic drug that exerts its effects via interference with microtubule function in parasites. To determine the utility of mebendazole as a potential treatment for vascular diseases involving proliferation of vascular smooth ...
Jintao Wang   +8 more
doaj   +1 more source

Endothelial cell-derived extracellular vesicles alter vascular smooth muscle cell phenotype through high-mobility group box proteins

open access: yesJournal of Extracellular Vesicles, 2020
The vascular endothelium and smooth muscle form adjacent cellular layers that comprise part of the vascular wall. Each cell type can regulate the other’s structure and function through a variety of paracrine effectors.
Michael J. Boyer   +7 more
doaj   +1 more source

Role of Vascular Smooth Muscle Cell Phenotypic Switching and Calcification in Aortic Aneurysm Formation.

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2019
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood vessel degenerates, leading to dilation and eventually vessel wall rupture.
Ploingarm Petsophonsakul   +9 more
semanticscholar   +1 more source

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