Results 91 to 100 of about 419,114 (213)

Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells

Acta Pharmaceutica Sinica B, 2018
Our previous studies found that mitochondrial uncouplers CCCP and niclosamide inhibited artery constriction and the mechanism involved AMPK activation in vascular smooth muscle cells. BAM15 is a novel type of mitochondrial uncoupler.
Yu Tai, Lanjun Li, Xuan Peng, Junxue Zhu, Xihai Mao, Nan Qin, Minghui Ma, Rong Huo, Yunlong Bai, Deli Dong   +9 more
doaj   +1 more source

CD14 Glycoprotein Expressed in Vascular Smooth Muscle Cells

Journal of Pharmacological Sciences, 2004
The inducible nitric oxide synthase (iNOS) expression in vascular smooth muscle cells is an important factor for pathogenesis of septic shock or multiple organ dysfunction syndrome.
Hyoung Chul Choi, Kwang Youn Lee
doaj   +1 more source

Mechanism of action and potential therapeutic targets of TGF-β-related signaling pathway and its downstream miRNA expression in pulmonary arterial hypertension

Frontiers in Pharmacology
Pulmonary hypertension is a major cardiovascular disease characterized by the persistent elevation of pulmonary artery pressure, leading to vascular remodeling, fibrosis, and endothelial dysfunction.
Yimo Huang, Wende Ma, Cen Guo, Cen Guo, Xiaoling Su   +4 more
doaj   +1 more source

Imbalance of Endothelium-derived Relaxing and Contracting Factors: A New Concept in Hypertension? [PDF]

, 2017
The endothelium has a strategical anatomical position between the circulating blood and vascular smooth muscle cells. It has recently been recognized that endothelial cells play an important regulatory role in the circulation.
Lüscher, T. F.
core  

Permanently proliferating rat vascular smooth muscle cell with maintained expression of smooth muscle characteristics, including actin of the vascular smooth muscle type. [PDF]

, 1980
Werner W. Franke, E Schmid, Joël Vandekerckhove, K. Weber   +3 more
openalex   +1 more source

NKX2-5 regulates vessel remodeling in scleroderma-associated pulmonary arterial hypertension

JCI Insight
NKX2-5 is a member of the homeobox-containing transcription factors critical in regulating tissue differentiation in development. Here, we report a role for NKX2-5 in vascular smooth muscle cell phenotypic modulation in vitro and in vascular remodeling ...
Ioannis Papaioannou, Athina Dritsoula, Ping Kang, Reshma S. Baliga, Sarah L. Trinder, Emma Cook, Xu Shiwen, Adrian J. Hobbs, Christopher P. Denton, David J. Abraham, Markella Ponticos   +10 more
doaj   +1 more source

Stimulation of vascular smooth muscle cell prostacyclin and prostaglandin E2 synthesis by plasma high and low density lipoproteins. [PDF]

, 1984
Kenneth B. Pomerantz, Alan R. Tall, S J Feinmark, Paul J. Cannon   +3 more
openalex   +1 more source

Somatic PDGFRB activating variants promote smooth muscle cell phenotype modulation in intracranial fusiform aneurysm

Journal of Biomedical Science
Background The fusiform aneurysm is a nonsaccular dilatation affecting the entire vessel wall over a short distance. Although PDGFRB somatic variants have been identified in fusiform intracranial aneurysms, the molecular and cellular mechanisms driving ...
Li Hao, Xiaolong Ya, Jiaye Wu, Chuming Tao, Ruochen Ma, Zhiyao Zheng, Siqi Mou, Yiming Ling, Yingxi Yang, Jiguang Wang, Yan Zhang, Qing Lin, Jizong Zhao   +12 more
doaj   +1 more source

Isolation and characterization of single vascular smooth muscle cells from spontaneously hypertensive rats. [PDF]

, 1989
Bradley J. Bolzon, D W Cheung
openalex   +1 more source

Design and use of an environmental control platform for studying vascular cell function in three-dimensional scaffolds [PDF]

, 2007
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2007.Includes bibliographical references (p. 33).Endothelial and smooth muscle cells are the core of the vascular system.
Jäätmaa, Iliana (Iliana Nicole Vera)
core