Results 91 to 100 of about 236,796 (264)

Fibrinogen is chemotactic for vascular smooth muscle cells

FEBS Letters, 1989
We studied the effect of fibrinogen on the migration of bovine aortic smooth muscle cells in culture, using a Neuro Probe 48‐well micro chemotaxis chamber. Fibrinogen stimulated the migration of the cells dose‐dependently at concentrations from 30 to 1OOO μg/ml.
Naito, Michitaka, Hayashi, Toshio, Kuzuya, Masafumi, Funaki, Chiaki, Asai, Kanichi, Kuzuya, Fumio   +5 more
openaire   +2 more sources

Celastrol‐Loaded Conductive Hydrogel Mitigates Myocardial Ischemia‐Reperfusion Injury and Restores Electrophysiological Function

Advanced Science, EarlyView.
Schematic illustration of the Pluronic F127 diacrylate/gelatin methacryloyl/poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate)/celastrol hydrogel (FGPC) for localized myocardial ischemia–reperfusion injury treatment. FGPC combines sustained celastrol delivery with PEDOT:PSS‐mediated conductive support to attenuate acute oxidative/inflammatory ...
Shixin Wang, Shaojie Chen, Chengzong Li, Hongyi Cheng, Jincheng Jiao, Xiafeng Peng, Yike Zhang, Wei Sun, Feng Zhang, Chang Cui, Minglong Chen   +10 more
wiley   +1 more source

Vascular Smooth Muscle Cells Contribute to Atherosclerosis Immunity

Frontiers in Immunology, 2019
Vascular smooth muscle cells (VSMCs) constitute the major cells in the media layer of arteries, and are critical to maintain the integrity of the arterial wall.
Desheng Hu, Desheng Hu, Changjun Yin, Shanshan Luo, Andreas J. R. Habenicht, Sarajo K. Mohanta   +5 more
doaj   +1 more source

Regulation of the cell magnesium in vascular smooth muscle

The Journal of Physiology, 1974
1. The relation between [Mg]o and the Mg content of the rat tail artery incubated in Ca‐free solutions was studied.2. Variation of [Mg]o in Ca‐free Krebs solution between 0·6 and 2·4 m m did not affect the cell Mg. In ATP‐depleted arteries, a sizeable fraction of the cell Mg was found to be proportional to [Mg]o.3.
openaire   +3 more sources

Vascular smooth muscle cell apoptosis in atherosclerosis [PDF]

International Journal of Experimental Pathology, 1999
Cell death has long been recognized within the vessel wall, in particular, in disease states such as atherosclerosis. The use of the term ‘necrotic core’ for the central lipid core of advanced lesions emphasizes this. Indeed there is obvious cell fragmentation and cell debris in areas of plaques, particularly the lipid core (Mitchinson et al.
openaire   +2 more sources

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

The epigenetic basis of vascular calcification: focus on histone modifications

European Journal of Medical Research
Histone modifications, including methylation, acetylation, and phosphorylation, are increasingly recognized as key contributors to the development of vascular calcification.
Junmin Huang, Changheng Li, Yunan Wang, Zekun Zhong, Tongtong Ma, Lu Chen, Hongying Luo, Ziqian Bi, Tianyang Wang, Huafeng Liu, Junfeng Hao, Peng Wang, Yongzhi Xu   +12 more
doaj   +1 more source

Endothelial–Vascular Smooth Muscle Cells Interactions in Atherosclerosis

Frontiers in Cardiovascular Medicine, 2018
Atherosclerosis is a chronic progressive inflammatory process that can eventually lead to cardiovascular disease (CVD). Despite available treatment, the prevalence of atherosclerotic CVD, which has become the leading cause of death worldwide, persists ...
Manna Li, Ming Qian, Kathy Kyler, Jian Xu   +3 more
doaj   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source