Results 181 to 190 of about 231,096 (267)

Soft Robotics and Advanced Technologies for Minimally Invasive Bioprinting: The Future of Internal Organ Repair

Advanced Science, EarlyView.
This review examines the evolution of bioprinting toward minimally invasive in situ strategies for internal organ regeneration. It defines the technological roadmap from handheld systems to advanced minimally invasive bioprinting platforms, positioning soft robotics as a core enabler.
Duc Tu Vu, Nhu An Phan, Sy Trung Ngo, Minh Tri Phan, Thanh‐An Truong, Chi Cong Nguyen, Phuoc Thien Phan, Hoang‐Phuong Phan, Thanh Nho Do, Mai Thanh Thai   +9 more
wiley   +1 more source

Blocking Sphingosine 1-phosphate Metabolism With Fingolimod Prevents the Progression of Vascular Smooth Muscle Cells Calcification in Chronic Kidney Disease. [PDF]

J Cell Physiol
Skafi N, Pelletier S, Soulage CO, Nahle S, Da Cruz BO, Othmani R, Briolay A, Reibel S, Vitale N, Hamade E, Badran B, Magne D, Buchet R, Stockler-Pinto MB, Fouque D, Mebarek S, Brizuela L.   +16 more
europepmc   +1 more source

Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models

Advanced Science, EarlyView.
Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka, Yuhei Higashi, Suguru Saito, Solmaz Pourgonabadi, Honami Honjoh, Sho Ishigaki, Peter C. Harris, Lisa M. Satlin, Michifumi Yamashita, Ryuji Morizane   +9 more
wiley   +1 more source

Impaired Efferocytosis of Pericytes and Vascular Smooth Muscle Cells in Diabetic Retinopathy. [PDF]

Cells
Gardiner TA, Little K, Stitt AW.
europepmc   +1 more source

Endometrial Epithelial Lactate Deficiency Drives CD8+ T‐Cells Dysregulation in Unexplained Recurrent Implantation Failure

Advanced Science, EarlyView.
Unexplained recurrent implantation failure (RIF) represents a significant clinical challenge. Our results demonstrate that reduced lactate production in the RIF endometrium impairs the suppression of cytotoxic CD8+ T‑cells, allowing their proliferation and thereby disrupting the local immune balance essential for successful embryo implantation.
Yuanlin He, Kang Ke, Qingxia Meng, Yichun Guan, Jichun Tan, Hong Lv, Boxian Huang, Chan Tian, Qinyan Zou, Mingxing An, Yao Gao, Jingjing Chen, Xiaoyu Wei, Xi Wang, Hongxia Ma, Yuan Lin, Feiyang Diao, Yayun Gu, Zhibin Hu   +18 more
wiley   +1 more source

[Retracted] MicroRNA-24-3p inhibition prevents cell growth of vascular smooth muscle cells by targeting Bcl-2-like protein 11. [PDF]

Exp Ther Med
Zhang H, Xue S, Feng Y, Shen J, Zhao J.
europepmc   +1 more source

Peptide‐Incorporated Biomaterials Promote Regeneration of Peripheral Nerve Injuries

Advanced Science, EarlyView.
Peptide‐incorporated biomaterials provide precise, tunable biological cues that mimic functional protein domains to regulate behaviors of neurons, Schwann cells, immune cells, and endothelial cells, thereby enhancing axon elongation, Schwann cell support, inflammatory microenvironment modulation, and vascularization, offering a promising alternative to
Zhiwei Zhao, Jianfeng Liu, Jincheng Li, Di Li, Jianxun Ding, Bin Liu   +5 more
wiley   +1 more source

Differential gene expression in peripheral vascular smooth muscle cells of patients with peripheral artery disease. [PDF]

Clin Exp Nephrol
Lee D, Kim JH, Lee DY.
europepmc   +1 more source

A Conformal Wearable Ultrasound Bioelectronics for Mechanotherapy Reprogramming of Fibroblast Plasticity via Wnt‐FGF10 Axis to Overcome Fibrotic Healing in Urethral Regeneration

Advanced Science, EarlyView.
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu, Xingxuan Zhang, Huan Zhang, Jun Wang, Fang Chen, Xiaojun Cai, Yichen Huang, Yuanyi Zheng   +7 more
wiley   +1 more source