Results 191 to 200 of about 513,814 (378)

De Novo Reconstruction of 3D Human Facial Images from DNA Sequence

Advanced Science, EarlyView.
This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen   +11 more
wiley   +1 more source

Isoquercitrin Alleviates Diabetic Nephropathy by Inhibiting STAT3 Phosphorylation and Dimerization

Advanced Science, EarlyView.
This study identified a natural compound, isoquercitrin, which significantly alleviated kidney inflammation and fibrosis by inhibiting STAT3 activity. Isoquercitrin forms a strong, noncovalent bond that directly binds to STAT3. Isoquercitrin binds to the pY+1 pocket of the SH2 domain of STAT3 via hydrogen bonding with Ser668, Gln635, and Gln633 ...
Chen Xuan, Donghui Chen, Shuangna Zhang, Chaofan Li, Qingyun Fang, Dinghua Chen, Jiabao Liu, Xin Jiang, Yingjie Zhang, Wanjun Shen, Guangyan Cai, Xiangmei Chen, Ping Li   +12 more
wiley   +1 more source

A large accumulation of non-muscle myosin occurs at first entry into M phase in rat vascular smooth-muscle cells [PDF]

, 1991
David J. Grainger, T R Hesketh, James C. Metcalfe, PL Weissberg   +3 more
openalex   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

Advanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin, Chuling Li, Zhaoyi Wu, Zhenquan Tang, Jingfang Xie, Guoquan Wei, Zhiwen Yang, Senlin Huang, Yijin Chen, Xinzhong Li, Yanmei Chen, Wangjun Liao, Yulin Liao, Guojun Chen, Hao Zheng, Jianping Bin   +15 more
wiley   +1 more source

Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells

Acta Pharmaceutica Sinica B, 2018
Our previous studies found that mitochondrial uncouplers CCCP and niclosamide inhibited artery constriction and the mechanism involved AMPK activation in vascular smooth muscle cells. BAM15 is a novel type of mitochondrial uncoupler.
Yu Tai, Lanjun Li, Xuan Peng, Junxue Zhu, Xihai Mao, Nan Qin, Minghui Ma, Rong Huo, Yunlong Bai, Deli Dong   +9 more
doaj  

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease.

Cell Stem Cell, 2016
R. Kramann, C. Goettsch, J. Wongboonsin, H. Iwata, R. Schneider, C. Kuppe, Nadine Kaesler, Monica Chang-Panesso, Flavia G Machado, Susannah Gratwohl, K. Madhurima, Joshua D. Hutcheson, Sanjay Jain, E. Aikawa, B. Humphreys   +14 more
semanticscholar   +1 more source

The dihydropyridine niguldipine modulates calcium and potassium currents in vascular smooth muscle cells

, 1989
Udo Klöckner, G Isenberg
openalex   +1 more source

Vascular Smooth Muscle Cell

, 2018
Ning Zhou, Shaunrick Stoll, Hongyu Qiu, Christiana Leimena   +3 more
openaire   +3 more sources

Advancements in Bio‐Integrated Flexible Electronics for Hemodynamic Monitoring in Cardiovascular Healthcare

Advanced Science, EarlyView.
This review explores the cutting‐edge development of bio‐integrated flexible electronics for real‐time hemodynamic monitoring in cardiovascular healthcare. It covers key physiological indicators, innovative sensing mechanisms, and materials considerations. This paper highlights the application of both invasive and non‐invasive devices in cardiovascular
Ke Huang, Zhiqiang Ma, Bee Luan Khoo
wiley   +1 more source

Role of PDGF-A expression in the control of vascular smooth muscle cell growth by transforming growth factor-beta. [PDF]

, 1990
R A Majack, Mark W. Majesky, Linda Goodman   +2 more
openalex   +1 more source