Results 211 to 220 of about 397,979 (354)
Peripheral nerve injury necessitates alternatives to autografts. This study combines magnetic nanoparticles, oriented PCL fibers, and Ppy to create a conductive, magnetically active scaffold. In vitro and in vivo experiments demonstrated enhanced downstream pathways of calcium signaling, as revealed by transcriptome analysis.
Zheyuan Fan+4 more
wiley +1 more source
The role of MicroRNAs in mesenchymal stem cell differentiation into vascular smooth muscle cells. [PDF]
Abolhasani S+3 more
europepmc +1 more source
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu+18 more
wiley +1 more source
Stromal cells from human long-term marrow cultures are mesenchymal cells that differentiate following a vascular smooth muscle differentiation pathway [PDF]
MC Galmiche+4 more
openalex +1 more source
Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells
L. Hilenski+4 more
semanticscholar +1 more source
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen+18 more
wiley +1 more source
Cathepsin D inhibits AGEs-induced phenotypic transformation in vascular smooth muscle cells. [PDF]
He X+7 more
europepmc +1 more source
ATF3 Deficiency Exacerbates Ageing‐Induced Atherosclerosis and Clinical Intervention Strategy
Targeting ATF3 with terazosin to against VSMC Senescence and atherosclerosis. TZ reduces the binding affinity of YTHDF2 to Atf3 mRNA, while enhancing mRNA stability. ATF3 promotes Atg7 transcription, enhancing autophagy. ATG7 binds to ATF3 in the cytoplasm, facilitating ATF3 translocation to the nucleus and establishing positive feedback. By modulating
Hao Nie+11 more
wiley +1 more source