Results 111 to 120 of about 1,797,457 (225)

Effects of biomechanical and biochemical stimuli on angio- and vasculogenesis in a complex microvasculature-on-chip

iScience, 2023
Summary: The endothelium of blood vessels is a vital organ that reacts differently to subtle changes in stiffness and mechanical forces exerted on its environment (extracellular matrix (ECM)).
Dario Ferrari, Arunima Sengupta, Lyong Heo, Laszlo Pethö, Johann Michler, Thomas Geiser, Vinicio A. de Jesus Perez, Wolfgang M. Kuebler, Soheila Zeinali, Olivier T. Guenat   +9 more
doaj  

Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation [PDF]

, 2014
A novel multiscale mathematical and computational model of the pulmonary circulation is presented and used to analyse both arterial and venous pressure and flow. This work is a major advance over previous studies by Olufsen et al. (Ann Biomed Eng 28:1281–
AC Burton, AJ Peacock, AJ Peacock, AR Pries, BI Levy, BN Steele, CA Figueroa, CA Taylor, Charles S. Peskin, Christopher Sainsbury, CW Li, D Mukerjee, DJ Patel, DJ Patel, E Hachulla, E Peskin, EH Hollander, EO Attinger, ER Weibel, FN Vosse van de, FY Zhuang, FY Zhuang, G Simonneau, Gareth D. A. Vaughan, GH Fonseca, GS Krenz, HBM Uylings, IE Vignon-Clementel, J Alastruey, J Fullana, JC Greenfield, JE Hall, JT Reeves, JW Lankhaar, K Azer, KS Matthys, L Formaggia, M. Umar Qureshi, Martin Johnson, Mette S. Olufsen, MS Olufsen, MS Olufsen, MS Olufsen, MS Pollanen, N Suwa, N Xiao, N. A. Hill, O Sitbon, P Dartevelle, P Herve, P Reymond, PH Bovendeerd, PJ Barnes, R Kato, RB Clipp, RB Clipp, RF Machado, RJ Barst, RL Evans, RM Tuder, RT Yen, S Singhal, SJ Sherwin, V Castelain, W Cousins, W Huang, WM Thurlbeck, WR Milnor, WW Nichols, Y Gao, Y Huo, Y Kawahira, YC Fung, YH Kim   +73 more
core   +1 more source

Evaluation of Peak Wall Stress in an Ascending Thoracic Aortic Aneurysm Using FSI Simulations: Effects of Aortic Stiffness and Peripheral Resistance [PDF]

Cardiovascular Engineering and Technology, Springer, 2018, 9 (4), pp.707-722, 2019
Purpose. It has been reported clinically that rupture or dissections in thoracic aortic aneurysms (TAA) often occur due to hypertension which may be modelled with sudden increase of peripheral resistance, inducing acute changes of blood volumes in the aorta.
arxiv  

Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women [PDF]

, 2002
Objective¿ Phytoestrogens have been postulated to protect against cardiovascular diseases, but few studies have focused on the effect of Western dietary phytoestrogen intake.
Bots, M.L., Grobbee, D.E., Lamberts, S.W.J., Lebrun, C.E.I., Peeters, P.H.M., Pijpe, A., Schouw, Y.T., van der, Staveren, W.A., van   +7 more
core   +3 more sources

Cholesterol Efflux: Does It Contribute to Aortic Stiffening?

Journal of Cardiovascular Development and Disease, 2018
Aortic stiffness during cardiac contraction is defined by the rigidity of the aorta and the elastic resistance to deformation. Recent studies suggest that aortic stiffness may be associated with changes in cholesterol efflux in endothelial cells.
Shutan Liao, Craig S. McLachlan
doaj   +1 more source

Impact of cocoa flavanol intake on age-dependent vascular stiffness in healthy men: a randomized, controlled, double-masked trial

AGE, 2015
Increased vascular stiffness, endothelial dysfunction, and isolated systolic hypertension are hallmarks of vascular aging. Regular cocoa flavanol (CF) intake can improve vascular function in healthy young and elderly at-risk individuals.
C. Heiss, R. Sansone, Hakima Karimi, Moritz Krabbe, D. Schuler, A. Rodriguez-Mateos, Thomas Kraemer, M. Cortese-Krott, G. Kuhnle, J. Spencer, H. Schroeter, M. Merx, M. Kelm   +12 more
semanticscholar   +1 more source

Small Vessel Disease in the Heart and Brain: Current Knowledge, Unmet Therapeutic Need and Future Directions [PDF]

, 2019
No abstract ...
Berry, C, Ford, TJ, Hainsworth, AH, Kaski, JC, Pereira, AC, Sidik, N, Touyz, RM   +6 more
core   +2 more sources

TARGETING VASCULAR SMOOTH MUSCLE CELL TO IMPROVE ARTERIAL STIFFNESS

Artery Research, 2017
Hypertension and arterial aging engage a plethora of key signaling pathways that act in concert to induce vascular smooth muscle cell (VSMC) phenotypic changes leading to vascular degeneration and extracellular matrix (ECM) changes responsible for ...
Patrick Lacolley
doaj   +1 more source

Frontiers in Vascular Stiffness

, 2023

semanticscholar   +1 more source

Mechanical cell-matrix feedback explains pairwise and collective endothelial cell behavior in vitro

, 2014
In vitro cultures of endothelial cells are a widely used model system of the collective behavior of endothelial cells during vasculogenesis and angiogenesis. When seeded in an extracellular matrix, endothelial cells can form blood vessel-like structures,
LaValley, Danielle J., Merks, Roeland M. H., Reinhart-King, Cynthia, Rens, Elisabeth G., van Oers, René F. M.   +4 more
core   +3 more sources