Advanced Science, EarlyView.Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
The role of vascular tissue stiffness and endothelial cellular stiffness
Japanese Journal of Thrombosis and Hemostasis, 2019 openaire +2 more sources
Inhibition of the histone methyltransferase EZH2 induces vascular stiffness. [PDF]
Clin Sci (Lond)Ibarrola J +5 more
europepmc +1 more source
[Primary study on recognition of vascular stiffness based on wavelet scattering neural network]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023 Ren S, Chen Z, Deng X, Fan Y, Sun A.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan +5 more
wiley +1 more source
Vascular Stiffness Is a Biomarker of Global Cardiovascular Risk
The Journal of Clinical Hypertension, 2014 Gary E, Sander, Thomas D, Giles
openaire +3 more sources
One-year exercise improves cognition and fitness and decreases vascular stiffness and reactivity to CO2 in amnestic mild cognitive impairment. [PDF]
J Alzheimers DisPenukonda S +8 more
europepmc +1 more source
Association of Blood Pressure-Related Increase in Vascular Stiffness on Other Measures of Target Organ Damage in Youth. [PDF]
Hypertension, 2022 Haley JE +18 more
europepmc +1 more source
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
Advanced Science, EarlyView.FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
Aging Two-Step: SOX9's Influence on Vascular Stiffness and Senescence. [PDF]
Circ ResBehzadi P, St Hilaire C.
europepmc +1 more source