Results 51 to 60 of about 1,799,199 (341)

Vascular Stiffness in Women With Systemic Lupus Erythematosus [PDF]

Hypertension, 2001
Abstract —Large-vessel manifestations of systemic lupus erythematosus (SLE), a multisystem disease characterized by disturbances in the immune system, include higher than expected rates of hypertension and cardiovascular disease.
F, Selzer, K, Sutton-Tyrrell, S, Fitzgerald, R, Tracy, L, Kuller, S, Manzi   +5 more
openaire   +2 more sources

Age and vascular aging: an unexplored frontier

Frontiers in Cardiovascular Medicine, 2023
Vascular age is an emerging field in cardiovascular risk assessment. This concept includes multifactorial changes in the arterial wall, with arterial stiffness as its most relevant manifestation, leading to increased arterial pressure and pulsatile flow ...
Laura del Mar González, Sara P. Romero-Orjuela, Fernando J. Rabeya, Valeria del Castillo, Darío Echeverri   +4 more
doaj   +1 more source

ARTERIAL STIFFNESS AS A RISK FACTOR FOR CEREBRAL VASCULAR LESIONS

Artery Research, 2018
Increased arterial stiffness, a biomarker of vascular aging, is a recognized subclinical organ damage, and may thus serve as predictor of cardiovascular disease.
Dariusz Gasecki
doaj   +1 more source

A decreased level of serum soluble Klotho is an independent biomarker associated with arterial stiffness in patients with chronic kidney disease. [PDF]

PLoS ONE, 2013
BACKGROUND: Klotho was originally identified in a mutant mouse strain unable to express the gene that consequently showed shortened life spans. In humans, low serum Klotho levels are related to the prevalence of cardiovascular diseases in community ...
Masashi Kitagawa, Hitoshi Sugiyama, Hiroshi Morinaga, Tatsuyuki Inoue, Keiichi Takiue, Ayu Ogawa, Toshio Yamanari, Yoko Kikumoto, Haruhito Adam Uchida, Shinji Kitamura, Yohei Maeshima, Kazufumi Nakamura, Hiroshi Ito, Hirofumi Makino   +13 more
doaj   +1 more source

Matrix Stiffness Induces Pericyte-Fibroblast Transition Through YAP Activation

Frontiers in Pharmacology, 2021
Vascular pericytes, important mural cells that retain progenitor cell properties and protect vascular integrity in healthy tissues, are often associated with tumor development, but their functions in cancer invasion remain elusive.
Feng Feng, Feng Feng, Xueyan Feng, Xueyan Feng, Di Zhang, Di Zhang, Qilong Li, Qilong Li, Li Yao, Li Yao   +9 more
doaj   +1 more source

Pressure and stiffness sensing together regulate vascular smooth muscle cell phenotype switching

Science Advances, 2022
Vascular smooth muscle cells (VSMCs) play a central role in the progression of atherosclerosis, where they switch from a contractile to a synthetic phenotype.
P. Swiatlowska, Brian Sit, Zhen Feng, Emilie Marhuenda, Ioannis Xanthis, Simona Zingaro, Matthew Ward, Xinmiao Zhou, Q. Xiao, C. Shanahan, G. Jones, Cheng-han Yu, Thomas Iskratsch   +12 more
semanticscholar   +1 more source

Impact of Sex on Ventricular‐Vascular Stiffness and Long‐Term Outcomes in Heart Failure With Preserved Ejection Fraction: TOPCAT Trial Substudy

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
Background Women have higher vascular stiffness with aging. The aim of this study was to characterize sex differences in vascular and ventricular structure and function, and to investigate the impact on the primary outcome in the TOPCAT trial (Treatment ...
A. Beale, S. Nanayakkara, D. Kaye
semanticscholar   +1 more source

Vascular Aging and Arterial Stiffness.

Arquivos brasileiros de cardiologia, 2022
Biological aging occurs as a result of the interaction between genetics, chronological age and external factors. It is the basis for new concepts of vascular aging, whose progression is determined by the difference between biological and chronological age.
Adriana Camargo, Oliveira, Pedro Miguel Guimarães Marques, Cunha, Priscila Valverde de Oliveria, Vitorino, Ana Luiza Lima, Souza, Gilcimar Divino, Deus, Audes, Feitosa, Eduardo Costa Duarte, Barbosa, Marco Mota, Gomes, Paulo Cesar B Veiga, Jardim, Weimar Kunz Sebba, Barroso   +9 more
openaire   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The Causal Relationship between Endothelin-1 and Hypertension: Focusing on Endothelial Dysfunction, Arterial Stiffness, Vascular Remodeling, and Blood Pressure Regulation

Life, 2021
Hypertension (HTN) is one of the most prevalent diseases worldwide and is among the most important risk factors for cardiovascular and cerebrovascular complications.
K. Kostov
semanticscholar   +1 more source