Results 11 to 20 of about 108,288 (268)

BMSC-Exosomes Carry Mutant HIF-1α for Improving Angiogenesis and Osteogenesis in Critical-Sized Calvarial Defects

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Repair and reconstruction of critical-sized bone defects has always been a difficult task in orthopedics. Hypoxia inducible factor-1α (HIF-1α) plays an important role in bone defect repair, it has the dual function of promoting osteogenesis and vascular ...
Chenting Ying   +8 more
doaj   +1 more source

VASCULAR REACTIONS IN VASCULAR HYPERTENSION [PDF]

open access: yesThe American Journal of The Medical Sciences, 1920
n ...
openaire   +1 more source

Vascular permeability, vascular hyperpermeability and angiogenesis [PDF]

open access: yesAngiogenesis, 2008
The vascular system has the critical function of supplying tissues with nutrients and clearing waste products. To accomplish these goals, the vasculature must be sufficiently permeable to allow the free, bidirectional passage of small molecules and gases and, to a lesser extent, of plasma proteins.
Nagy, Janice A.   +4 more
openaire   +2 more sources

Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing

open access: yesFrontiers in Pharmacology, 2023
The lack of vascularization associated with deep burns delays the construction of wound beds, increases the risks of infection, and leads to the formation of hypertrophic scars or disfigurement.
Hengyue Song   +26 more
doaj   +1 more source

Vascularization of the kidney of the ground squirrel (Citellus citellus) in comparison with other experimental animals [PDF]

open access: yesVeterinarski Glasnik, 2015
Ground squirrel is the only representative of its genus in our country. As experimental animal is used in microbiology, parasitology, immunology and pharmacology.
Blagojević Miloš   +9 more
doaj   +1 more source

Bioprinting for vascular and vascularized tissue biofabrication [PDF]

open access: yesActa Biomaterialia, 2017
Bioprinting is a promising technology to fabricate design-specific tissue constructs due to its ability to create complex, heterocellular structures with anatomical precision. Bioprinting enables the deposition of various biologics including growth factors, cells, genes, neo-tissues and extra-cellular matrix-like hydrogels. Benefits of bioprinting have
Pallab, Datta   +2 more
openaire   +2 more sources

Modeling Endothelialized Hepatic Tumor Microtissues for Drug Screening

open access: yesAdvanced Science, 2020
Compared to various traditional 2D approaches, the scaffold‐based 3D tumor models have emerged as an effective strategy to investigate the complex mechanisms behind cancer progression and responses to drug treatments, by providing biomimetic ...
Ying Wang   +7 more
doaj   +1 more source

Strategies for Improving Vascularization in Kidney Organoids: A Review of Current Trends

open access: yesBiology, 2023
Kidney organoids possess the potential to revolutionize the treatment of renal diseases. However, their growth and maturation are impeded by insufficient growth of blood vessels.
Ran Konoe, Ryuji Morizane
doaj   +1 more source

MicroRNAs in Vascular Biology and Vascular Disease [PDF]

open access: yesJournal of Cardiovascular Translational Research, 2010
MicroRNAs (miRNAs) have emerged as a novel class of endogenous, small, non-coding RNAs that negatively regulate over 30% of genes in a cell via degradation or translational inhibition of their target mRNAs. Functionally, an individual miRNA is important as a transcription factor because it is able to regulate the expression of its multiple target genes.
openaire   +2 more sources

Vascular Teams in Peripheral Vascular Disease

open access: yesJournal of the American College of Cardiology, 2019
Peripheral vascular disease affects millions of individuals worldwide, and results in significant morbidity and mortality. The complex nature of the disease, the presence of multiple comorbidities, and the existence of a wide variety of therapeutic options suggests that a multidisciplinary approach to treatment has the potential to improve care of ...
Dhaval, Kolte   +11 more
openaire   +2 more sources

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