Results 21 to 30 of about 135,786 (259)

Spatial and temporal patterns of bone formation in ectopically pre-fabricated, autologous cell-based engineered bone flaps in rabbits [PDF]

, 2008
Biological substitutes for autologous bone flaps could be generated by combining flap pre-fabrication and bone tissue engineering concepts. Here, we investigated the pattern of neotissue formation within large pre-fabricated engineered bone flaps in ...
Pierer, Gerhard, Oliver Scheufler, Galli, Raffaele, Scheufler, Oliver, Braccini, Alessandra, David J. Wendt, Heberer, Michael, Michael Heberer, Gerhard Pierer, Raffaele Galli, Dirk J. Schaefer, Gasser, Juerg A., Jürg A. Gasser, Martin, Ivan, Ivan Martin, Jaquiery, Claude, Claude Jaquiery, Wendt, David J., Alessandra Braccini, Schaefer, Dirk J.   +19 more
core   +1 more source

Modeling Endothelialized Hepatic Tumor Microtissues for Drug Screening

Advanced Science, 2020
Compared to various traditional 2D approaches, the scaffold‐based 3D tumor models have emerged as an effective strategy to investigate the complex mechanisms behind cancer progression and responses to drug treatments, by providing biomimetic ...
Ying Wang, Ranjith Kumar Kankala, Jianting Zhang, Liuzhi Hao, Kai Zhu, Shibin Wang, Yu Shrike Zhang, Aizheng Chen   +7 more
doaj   +1 more source

Strategies for Improving Vascularization in Kidney Organoids: A Review of Current Trends

Biology, 2023
Kidney organoids possess the potential to revolutionize the treatment of renal diseases. However, their growth and maturation are impeded by insufficient growth of blood vessels.
Ran Konoe, Ryuji Morizane
doaj   +1 more source

Generation of human adult mesenchymal stromal/stem cells expressing defined xenogenic vascular endothelial growth factor levels by optimized transduction and flow cytometry purification [PDF]

, 2012
Adult mesenchymal stromal/stem cells (MSCs) are a valuable source of multipotent progenitors for tissue engineering and regenerative medicine, but may require to be genetically modified to widen their efficacy in therapeutic applications.
Melly, L., Arnaud Scherberich, Ludovic Melly, Wolff, T., Michael Heberer, Heberer, Michael, Marsano, Anna, Banfi, Andrea, Scherberich, Arnaud, Liliane Christ, Andrea Banfi, Helmrich, Uta, Martin, Ivan, Wolff, Thomas, Christ, L., Christ, Liliane, Helmrich, U., Scherberich, A., Anna Marsano, Marsano, A., Melly, Ludovic, Uta Helmrich, Ivan Martin, Martin, I., Heberer, M., Banfi, A., Thomas Wolff   +26 more
core   +1 more source

Reconstruction of Large Skeletal Defects: Current Clinical Therapeutic Strategies and Future Directions Using 3D Printing

Frontiers in Bioengineering and Biotechnology, 2020
The healing of bone fractures is a well-orchestrated physiological process involving multiple cell types and signaling molecules interacting at the fracture site to replace and repair bone tissue without scar formation.
Luciano Vidal, Carina Kampleitner, Meadhbh Á. Brennan, Meadhbh Á. Brennan, Alain Hoornaert, Alain Hoornaert, Pierre Layrolle   +6 more
doaj   +1 more source

Gut-Spleen Axis: Microbiota via Vascular and Immune Pathways Improve Busulfan-Induced Spleen Disruption

mSphere, 2023
Fecal microbiota transplantation (FMT) is an effective means of modulating gut microbiota for the treatment of many diseases, including Clostridioides difficile infections. The gut-spleen axis has been established, and this is involved in the development
Hanhan Fang, Xiaohui Feng, Tao Xu, Ruqing Zhong, Dongxin Lu, Hongfu Zhang, Wei Shen, Yong Zhao, Liang Chen, Junjie Wang   +9 more
doaj   +1 more source

Vascularization Tissue Engineering [PDF]

, 2008
Tissue engineering has been an active field of research for several decades now. However, the amount of clinical applications in the field of tissue engineering is still limited.
Rivron, N.C., Rouwkema, Jeroen, van Blitterswijk, Clemens   +2 more
core   +1 more source

DIAGNOSTIC VALUE OF ULTRASOUND COLOR DOPPLER MAPPING IN EARLY DETECTION OF BREAST CANCER

Сибирский онкологический журнал, 2020
Background. Experimental data suggest that tumor growth depends on angiogenesis. Once the tumor reaches a size of up to a 1 mм in diameter, a further increase in the population of tumor cells requires the growth of new blood vessels.
E. A. Busko, V. V. Semiglazov, A. V. Mishchenko, A. S. Shishova, V. O. Smirnova, E. V. Kostromina, A. V. Chernaya, A. S. Artemieva, P. V. Kryvorotko   +8 more
doaj   +1 more source

Bioprinting and In Vitro Characterization of an Eggwhite-Based Cell-Laden Patch for Endothelialized Tissue Engineering Applications

Journal of Functional Biomaterials, 2021
Three-dimensional (3D) bioprinting is an emerging fabrication technique to create 3D constructs with living cells. Notably, bioprinting bioinks are limited due to the mechanical weakness of natural biomaterials and the low bioactivity of synthetic peers.
Yasaman Delkash, Maxence Gouin, Tanguy Rimbeault, Fatemeh Mohabatpour, Petros Papagerakis, Sean Maw, Xiongbiao Chen   +6 more
doaj   +1 more source

The ROX@PDA@PCL vascularized bionic nerve conduit facilitates the restoration of nerve defects

Frontiers in Neurology
Previous research has highlighted the pivotal role of angiogenesis in facilitating nerve function repair following nerve injury. In this study, we employed polydopamine (PDA) to modify polycaprolactone (PCL) and subsequently loaded it with roxadustat ...
Daoyi Lin, Daoyi Lin, Jun Peng, Yichong Zhang, Xiaoping Wang, Xiaodong Xu, Jing Jia   +6 more
doaj   +1 more source