Results 81 to 90 of about 126,160 (310)

Host-Dependent Vascularization in Cardiac Tissue Engineering

, 2021
Thesis (Ph.D.)--University of Washington, 2021Cardiac tissue engineering could address the growing need for donor hearts by supplying an alternative source of human myocardium.
Brady, Eileen L
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Printing of vessels for small functional tissues – a preliminary study

Current Directions in Biomedical Engineering, 2020
Vascularization of bioprinted constructs to ensure sufficient nutrient supply still remains to be a significant task in the tissue engineering community.
Polley Christian, Kussauer Sophie, David Robert, Barkow Phillip, Mau Robert, Seitz Hermann   +5 more
doaj   +1 more source

Astrocyte heterogeneity in brain metastases

Molecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver, Neibla Priego, Manuel Valiente   +2 more
wiley   +1 more source

Vascular mechanical forces and vascular diseases

Journal of Advanced Research
Blood vessels are continuously exposed to mechanical forces, mainly including shear stress, cyclic stretch, and hydrostatic pressure. These forces regulate the functions of endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) through complex mechanosensing and signal transduction pathways, which are essential for maintaining vascular ...
Shiwen Liu, Jun Cai, Zhenzhen Chen
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The role of vascularization in 3-D tissue engineering

, 2004
The role of vascularization in 3-D tissue engineering was studied. Mouse fat, angiogenic growth factors, adult human stem cells and fat tissue have been inserted and subsequent tissue growth was monitored.
Messina, A., Stillaert, F., Lokmic, Z., Morrison, W.A., Hofer, S.O.P., Mitchell, G.M., Thompson, E.W., Tanaka, Y., Findlay, M., Idrizi, R., Ramakrishnan, A.   +10 more
core  

Vascular [PDF]

Operative Neurosurgery, 2019
Adam S, Arthur, I Josh, Abecassis, Karl R, Abi-Aad, Felipe C, Albuquerque, Rami O, Almefty, Rami James N, Aoun, Daniel L, Barrow, Joshua, Bederson, Bernard R, Bendok, Andrew F, Ducruet, Andrew A, Fanous, Vernard S, Fennell, Bruno C, Flores, Christoph J, Griessenauer, Louis J, Kim, Michael R, Levitt, William J, Mack, Justin, Mascitelli, Elliott, Min, J, Mocco, Simon, Morr, John D, Nerva, Alexandra E, Richards, Clemens M, Schirmer, Alfred P, See, Kenneth V, Snyder, Fucheng, Tian, Brian P, Walcott, Matthew E, Welz   +28 more
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Detection of pigment epithelial detachment vascularization in age-related macular degeneration using phase-variance OCT angiography

, 2015
Scott M McClintic,1 Dae Yu Kim,2 Jeff Fingler,3 Susan Garcia,4 Robert J Zawadzki,4 Lawrence S Morse,4 Susanna S Park,4 Scott E Fraser,3 John S Werner,4 Jason P Ruggiero,5 Daniel M Schwartz6 1Department of Ophthalmology, Casey Eye Institute, Oregon Health
Kim DY, Fingler J, Werner JS, Park SS, Schwartz DM, McClintic SM, Garcia S, Morse LS, Zawadzki RJ, Fraser SE, Ruggiero JP   +10 more
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