Results 61 to 70 of about 183,177 (315)

Pulmonary Dysfunction Is Associated With Sleep Study Abnormalities in Children With Sickle Cell Disease: A Multicenter Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash, Anis Rabbani Nourani, A. K. M. Fazlur Rahman, Dima Ezmigna, Tarig Ali‐Dinar   +4 more
wiley   +1 more source

A Protocol for the In Vitro Culturing of Vascularized Pancreatic Islet Organoids

Bioengineering
This study presents a protocol for co-culturing pancreatic islet cell clusters derived from pancreatic tissue with human umbilical vein endothelial cells (HUVECs) on Matrigel using a specialized culture medium to form vascularized pancreatic islet ...
Pengkun Song, Yue Wang, Junya Peng, Lei Liu, Lei Du   +4 more
doaj   +1 more source

Role of the porous structure of the bioceramic scaffolds in bone tissue engineering [PDF]

, 2010
The porous structure of biomaterials plays a critical role in improving the efficiency of biomaterials in tissue engineering. Here we fabricate successfully porous bioceramics with accurately controlled pore parameters, and investigate the effect of pore
Bai Feng, Chang Jiang, Dai Rong, Lei Chen, Lin Li, Lu Jianxi, Sun Xiaojiang, Wang Zhen   +7 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Mechanically Tunable Biofabricated Channels Enable Mimicking Arterial Pulsatility and Dynamic Tissue Actuation

Small Science
Dynamic alteration of blood vessel geometry is an inherent feature of the circulatory system. However, while the engineering of multiscale, branched, and interconnected blood vessels has been well explored, mimicking the dynamic behavior (e.g., pulsatile
Cécile Bosmans, Malin Becker, Liliana S. Moreira Teixeira, Jeroen Leijten   +3 more
doaj   +1 more source

Navigating challenges in human pluripotent stem cell-derived islet therapy for type 1 diabetes

Frontiers in Immunology
In the past two decades, several tissues have been generated from the differentiation of human pluripotent stem cells (hPSCs) to model development or disease, and for use in drug testing and cell replacement therapies.
Mohammed Usama, Mohammed Usama, Ying Deng, Ying Deng, Yiran Chen, Théa Milland, Théa Milland, Mohan Malleshaiah, Mohan Malleshaiah, Mohan Malleshaiah, Yasaman Aghazadeh, Yasaman Aghazadeh, Yasaman Aghazadeh   +12 more
doaj   +1 more source

An In Vivo Platform for Rebuilding Functional Neocortical Tissue

Bioengineering, 2023
Recent progress in cortical stem cell transplantation has demonstrated its potential to repair the brain. However, current transplant models have yet to demonstrate that the circuitry of transplant-derived neurons can encode useful function to the host ...
Alexandra Quezada, Claire Ward, Edward R. Bader, Pavlo Zolotavin, Esra Altun, Sarah Hong, Nathaniel J. Killian, Chong Xie, Renata Batista-Brito, Jean M. Hébert   +9 more
doaj   +1 more source

Predictivity of clinical, laboratory and imaging findings in diagnostic definition of palpable thyroid nodules. A multicenter prospective study [PDF]

, 2018
PURPOSE: To assess the role of clinical, biochemical, and morphological parameters, as added to cytology, for improving pre-surgical diagnosis of palpable thyroid nodules.
Avenia, Nicola, Badii, Benedetta, Bellantone, Rocco, Boschin, Isabella Merante, Cal\uf2, Pietro Giorgio, Chiofalo, Maria Grazia, DI MAIO, Massimo, Fulciniti, Franco, Gallo, Ciro, Lombardi, Celestino Pio, Nicolosi, Angelo, Panebianco, Vincenzo, Pelizzo, Maria Rosa, Perigli, Giuliano, Perrone, Francesco, Pezzullo, Luciano, Polistena, Andrea, Ristagno, Serenella, Signoriello, Simona   +18 more
core   +4 more sources

Dietary Protein Intake and Peritoneal Protein Losses in Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) patients lose protein in their waste dialysate, potentially increasing their risk for malnutrition. We wished to determine whether there was any association between losses and dietary protein intake (DPI). Methods DPI was assessed from 24‐h dietary recall using Nutrics software.
Haalah Shaaker, Andrew Davenport
wiley   +1 more source

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression [PDF]

, 2012
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Abramsson, Adams, Aicher, Armulik, Arosarena, Augustin, Benedito, Bergers, Blouw, Brastianos, Cancer Genome Atlas Research Network, Carmeliet, Cathrin J. Czupalla, Cattelino, Chien, Claxton, Corada, Daneman, Daneman, Devraj, Ernesto Bockamp, Estrach, Fisher, Franco, Gerhardt, Gerhardt, Harada, Harrington, Hellström, Jadranka Macas, Jakobsson, Jenny Zinke, Kamino, Karl H. Plate, Kavi Devraj, Kotliarova, Li, Liebner, Liebner, Liebner, Liebner, Lobov, Lobov, Lucero, Machein, Mailhos, Makoto M. Taketo, Marco Reis, Marcus Fruttiger, McCarty, Min, Nicole Ziegler, Noguera-Troise, Olsson, Phng, Phng, Rosario Heck, Saharinen, Sascha Seidel, Schneider, Segarra, Siekmann, Smadja, Smolich, Sonja Thom, Stefan Liebner, Stefanie Dimmeler, Stenman, Streit, Thomas, Vleminckx, Willert, Williams, Wolburg, Yano, Yano, Yoshio-Hoshino, Zhang, Zhang, Zhou   +79 more
core   +1 more source