Results 71 to 80 of about 135,786 (259)
Printing of vessels for small functional tissues – a preliminary study
Vascularization of bioprinted constructs to ensure sufficient nutrient supply still remains to be a significant task in the tissue engineering community.
Polley Christian +5 more
doaj +1 more source
Host-Dependent Vascularization in Cardiac Tissue Engineering
Thesis (Ph.D.)--University of Washington, 2021Cardiac tissue engineering could address the growing need for donor hearts by supplying an alternative source of human myocardium.
Brady, Eileen L
core
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
Magnetic blood vessel devices as vascularization models
Mimicking the vascularization of the native tissue microenvironment is a widely studied yet still challenging field of research. In this work, artificial blood vessels were fabricated in novel scaffolds made of gelatin and magnetic nanoparticles.
Cabral, Joaquim M.S. +5 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Background: We conducted our study on 1110 patients with breast masses in order to investigate different aspects of power Doppler sonography (PDS) for differentiating between benign and malignant breast lesions and their prognostication.
Mehri Sirous +4 more
doaj
The role of vascularization in 3-D tissue engineering
The role of vascularization in 3-D tissue engineering was studied. Mouse fat, angiogenic growth factors, adult human stem cells and fat tissue have been inserted and subsequent tissue growth was monitored.
Messina, A. +10 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Scott M McClintic,1 Dae Yu Kim,2 Jeff Fingler,3 Susan Garcia,4 Robert J Zawadzki,4 Lawrence S Morse,4 Susanna S Park,4 Scott E Fraser,3 John S Werner,4 Jason P Ruggiero,5 Daniel M Schwartz6 1Department of Ophthalmology, Casey Eye Institute, Oregon Health
Kim DY +10 more
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