Results 51 to 60 of about 183,177 (315)

Crosstalk Between Long Non-coding RNAs, Micro-RNAs and mRNAs: Deciphering Molecular Mechanisms of Master Regulators in Cancer

Frontiers in Oncology, 2019
Cancer is a complex disease, and its study requires deep understanding of several biological processes and their regulation. It is an accepted fact that non-coding RNAs are vital components of the regulation and cross-talk among cancer-related signaling ...
Eduardo López-Urrutia, Lilia P. Bustamante Montes, Diego Ladrón de Guevara Cervantes, Carlos Pérez-Plasencia, Carlos Pérez-Plasencia, Alma D. Campos-Parra   +5 more
doaj   +1 more source

Understanding Multicellularity: The Functional Organization of the Intercellular Space [PDF]

, 2019
The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration,
Bich, Leonardo, Moreau, Jean-Francois, Pradeu, Thomas   +2 more
core   +11 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

3D Printed TCP-Based Scaffold Incorporating VEGF-Loaded PLGA Microspheres for Craniofacial Tissue Engineering [PDF]

, 2017
Objective Vascularization is a critical process during bone regeneration/repair and the lack of tissue vascularization is recognized as a major challenge in applying bone tissue engineeringmethods for cranial and maxillofacial surgeries.
D. Lobner, E. Dashtimoghadam, F. Bastami, F. Fahimipour, K. Khoshroo, L. Tayebi, M. Rasoulianboroujeni, M. Tahriri   +7 more
core   +2 more sources

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Hubungan Antara Cell Death Dengan Vaskularisasi Dan Reaksi Limfosit Pada Kanker Serviks Jenis Squamous Cell Carcinoma

Magna Medika, 2016
Latar Belakang: Kanker serviks merupakan masalah kesehatan yang menempati angka kejadian dan angka kematian tertinggi ke 4 di dunia sedangkan di Indonesia menjadi penyebab kematian di urutan ke 2.
Bramantyas Kusuma Hapsari
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Mscs Apoptotic Vesicles Attenuated Endothelial Cell Ferroptosis For Angiogenesis

International Dental Journal
Aim or purpose: Investigating adipose-derived stem cell apoptotic vesicles (ASCs-apoVs) as angiogenic mediators through ferroptosis inhibition for enhanced diabetic wound repair.
Jinxin Kuang, Liu Jiani, Geng Dou
doaj   +1 more source

The Emerging Role of the Prokineticins and Homeobox Genes in the Vascularization of the Placenta: Physiological and Pathological Aspects

Frontiers in Physiology, 2020
Vasculogenesis and angiogenesis are key processes of placental development, which occur throughout pregnancy. Placental vasculogenesis occurs during the first trimester of pregnancy culminating in the formation of hemangioblasts from intra-villous stem ...
Nadia Alfaidy, Nadia Alfaidy, Nadia Alfaidy, Sophie Brouillet, Gayathri Rajaraman, Bill Kalionis, Pascale Hoffmann, Pascale Hoffmann, Pascale Hoffmann, Tiphaine Barjat, Mohamed Benharouga, Padma Murthi, Padma Murthi   +12 more
doaj   +1 more source

Effect of dithiocarbamate thiram on Wistar rat growth plate and articular cartilage [PDF]

, 2012
Avaliou-se o efeito do tirame, ditiocarbamato largamente utilizado na agricultura como antifúngico e repelente de roedores, na ossificação endocondral de mamíferos, usando, como modelo, ratos Wistar.
Cabrita, AS, Capela e Silva, F, Fialho, L, Pereira, AMF, Rafael, A   +4 more
core   +3 more sources