Results 91 to 100 of about 1,741 (203)

CURRENT STATUS OF VASCULARIZED COMPOSITE ALLOGRAFTS TRANSPLANT [PDF]

, 2019
Introduction. The field of composite tissue allotransplatation became a clinical reality since first hand transplant performed in 1998 at Lyon, France and has been progressing over the past two decades.
Ioan Lascăr, Andreea Grosu-Bularda, Răzvan Nicolae Teodoreanu   +2 more
core   +1 more source

Organ Transplantation: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
Organ transplantation success relies on precise modulation of the alloimmune response across distinct temporal phases of rejection. Hyperacute rejection results from preformed antibodies activating complement and causing thrombosis, while acute rejection involves T cell‐ and antibody‐mediated mechanisms that drive endothelial activation and ...
Xinqiang Li, Ruidong Ding, Jinzhen Cai
wiley   +1 more source

Machine Perfusion Enables 24-h Preservation of Vascularized Composite Allografts in a Swine Model of Allotransplantation [PDF]

International audienceThe current gold standard for preserving vascularized composite allografts (VCA) is 4 degrees C static cold storage (SCS), albeit muscle vulnerability to ischemia can be described as early as after 2 h of SCS. Alternatively, machine
Goutard, Marion, Bertheuil, Nicolas, Berkane, Yanis, How, Ira Doressa Anne L., Lellouch, Alexandre G, Andrews, Alec R., Rosales, Ivy A., A. Randolph, Mark, Uygun, Korkut, Filz von Reiterdank, Irina, L. Cetrulo Jr, Curtis, Pendexter, Casie A., Tawa, Pierre, de Vries, Reinier J., Romano, Golda, Pozzo, Victor, Lancia, Hyshem H.   +16 more
core   +2 more sources

Psychosocial factors and medication adherence among recipients of vascularized composite allografts

SAGE Open Medicine, 2020
Objectives: Psychosocial factors are important predictors of medication adherence, and subsequently graft survival, in solid organ transplantation. Early experiences suggest this may also be the case in vascularized composite allotransplantation. Methods:
Sarah E Van Pilsum Rasmussen, Alexander Ferzola, Carisa M Cooney, Jaime T Shores, WP Andrew Lee, Emily Goldman, Christina L Kaufman, Gerald Brandacher, Dorry L Segev, Macey L Henderson   +9 more
doaj   +1 more source

Local and Systemic Immunologic Profiles Differentiate Accepted and Rejected Islet Grafts in a Rat Anterior Chamber Model

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
The anterior chamber of the eye (ACE) provides a minimally invasive, immune‐privileged site for pancreatic islet engraftment. However, loss of immune privilege during revascularization can trigger inflammation and graft rejection. In this study, we compared ocular and systemic immunologic responses associated with accepted and rejected islet allografts
Jae-young Lee, Choun-Ki Joo, Asif I. Shawl, Hyun Soo Lee, Poorani Gurumallesh Prabu   +4 more
wiley   +1 more source

Exploring Costimulatory Blockade-Based Immunologic Strategies in Transplantation: Are They a Promising Immunomodulatory Approach for Organ and Vascularized Composite Allotransplantation? [PDF]

J Pers Med
The field of transplantation, including the specialized area of vascularized composite allotransplantation (VCA), has been transformed since the first hand transplant in 1998. The major challenge in VCA comes from the need for life-long immunosuppressive
Grosu-Bularda A, Hodea FV, Zamfirescu D, Stoian A, Teodoreanu RN, Lascăr I, Hariga CS.   +6 more
europepmc   +2 more sources

Comments on “Cryopreserved Total Skin Allografts From Living Donors for Complex Wound Management: A New Paradigm in Regenerative Wound Care”

International Wound Journal, Volume 23, Issue 3, March 2026.
Julei Ma, Bing Wang, Bo Chen
wiley   +1 more source

Chronic Rejection in Human Vascularized Composite Allotransplantation (Hand and Face Recipients): An Update.

, 2016
Upper extremity allotransplantation (UEA) is the more common type of vascularized composite allotransplantation of which more than 80 patients have benefited worldwide.
Gazarian A, Badet L, Kanitakis J, Petruzzo P, Baran R, Morelon E.   +5 more
core   +1 more source

Emerging Implications for Extracellular Matrix-Based Technologies in Vascularized Composite Allotransplantation

, 2016
Despite recent progress in vascularized composite allotransplantation (VCA), limitations including complex, high dose immunosuppression regimens, lifelong risk of toxicity from immunosuppressants, acute and most critically chronic graft rejection, and ...
Ricardo Londono, Vijay S. Gorantla, Stephen F. Badylak   +2 more
core   +1 more source

Topical Application of Human Wharton’s Jelly Mesenchymal Stem Cells Accelerates Mouse Sciatic Nerve Recovery and is Associated with Upregulated Neurotrophic Factor Expression

Cell Transplantation, 2019
Peripheral nerve regeneration following injury is often slow and impaired, which results in weakened and denervated muscle with subsequent atrophy.
Aline Yen Ling Wang, Charles Yuen Yung Loh, Hsin-Hsin Shen, Sing-Ying Hsieh, Ing-Kae Wang, Sheng-Hao Chuang, Fu-Chan Wei   +6 more
doaj   +1 more source