Results 131 to 140 of about 4,131 (170)
Does Vasculogenic Mimicry Exist in Astrocytoma? [PDF]
Vasculogenic mimicry (VM) has been observed in melanoma and in some non-melanoma tumor types. It is unknown whether a similar VM phenomenon exists in astrocytoma. The present study was to examine 45 astrocytomas (including World Health Organization grade II 15 cases, grade III 15 cases, and grade IV 15 cases) by CD34 endothelial marker periodic acid ...
Zhong-Ping Chen
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Vasculogenic Mimicry—An Overview
2022Vasculogenic mimicry (VM), a tumor microcirculation model found in melanoma in the last 20 years, is a vascular channel-like structure composed of tumor cells, but without endothelial cells, that stains positive for periodic acid-Schiff (PAS) and negative staining for CD31.
Emily, Marques Dos Reis +1 more
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Advanced research on vasculogenic mimicry in cancer
AbstractVasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel‐like networks that provide adequate blood supply for tumour growth. A variety of molecule mechanisms and signal pathways participate in VM induction.
Lili Qiao, Fengjun Liu, Deguo Xu
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Histochemical Staining of Vasculogenic Mimicry
2022Vasculogenic mimicry (VM) describes a new tumor microvascular paradigm of non-endothelial cells, where aggressive cancer cells independent of angiogenesis acquire the ability to fluid-conducting vessels. VM shows worse 5-year overall survival in cancer that suggesting that VM could be a promising surgical and effective adjuvant therapy strategy in ...
Saber, Imani +3 more
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Vasculogenic Mimicry in a 3D Model In Vitro
2022Increasing studies on vasculogenic mimicry (VM) have shown that the hypoxic microenvironment and the presence of endothelial cell play an important role in regulating tumor phenotype and aggressiveness. Thus, the representation of these factors in vitro becomes necessary to mimic VM.
Emily, Marques Dos Reis +2 more
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Signalling pathways in vasculogenic mimicry
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2010Solid tumour growth is dependent on the development of an adequate blood supply. For years, sprouting angiogenesis has been considered an exclusive mechanism of tumour vascularization. However, over the last years, several other mechanisms have been identified, including vessel-co-option, intussusception, recruitment of endothelial precursor cells ...
Paulis, Y.W.J. +4 more
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Clinical significance of vasculogenic mimicry in human gliomas [PDF]
Vasculogenic mimicry (VM) is known as non-endothelial tumor cell-lined microvascular channels in aggressive tumors. We have previously found the presence of VM in high-grade gliomas. In this study, we aimed to identify VM patterns in gliomas and to explore their clinical significance.
Ke Sai, Ho-Keung Ng, Zhong-Ping Chen
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Investigation of vasculogenic mimicry in intracranial hemangiopericytoma
Molecular Medicine Reports, 2011Vasculogenic mimicry (VM) has increasingly been recognized as a form of angiogenesis. Previous studies have shown that the existence of VM is associated with poor clinical prognosis in certain malignant tumors. However, whether VM is present and clinically significant in intracranial hemangiopericytoma (HPC) is unknown.
Zhen, Zhang +3 more
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Slug promoted vasculogenic mimicry in hepatocellular carcinoma
AbstractVasculogenic mimicry (VM) refers to the unique capability of aggressive tumour cells to mimic the pattern of embryonic vasculogenic networks. Epithelial–mesenchymal transition (EMT) regulator slug have been implicated in the tumour invasion and metastasis of human hepatocellular carcinoma (HCC).
Baocun Sun, Xiulan Zhao, Na Che
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The involvement of apoptosis in melanoma vasculogenic mimicry
Melanoma Research, 2007During development, the formation and remodeling of the primary vascular network occurs by vasculogenesis and angiogenesis. In 1999, the concept of vasculogenic mimicry was introduced to describe the unique ability of highly aggressive tumor cells to form a capillary-like structure and a matrix-rich patterned network in three-dimensional culture that ...
Amalia A, Vartanian +3 more
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