Results 101 to 110 of about 82,899 (261)

Vasoactive intestinal peptide alleviates osteoarthritis effectively via inhibiting NF-κB signaling pathway

Journal of Biomedical Science, 2018
Background To investigate the treatment effect of vasoactive intestinal peptide (VIP) on osteoarthritis (OA) and the relative mechanism. Method The OA model on the SD rat knee was established using the modified Hulth method, and the recombinant pcDNA3.1+/
Yaozhong Liang, Shu Chen, Yuhao Yang, Chunhai Lan, Guowei Zhang, Zhisheng Ji, Hongsheng Lin   +6 more
doaj   +1 more source

Protective Intestinal Effects of Pituitary Adenylate Cyclase Activating Polypeptide [PDF]

, 2016
Pituitary adenylate cyclase activating polypeptide (PACAP) is an endogenous neuropeptide widely distributed throughout the body, including the gastrointestinal tract. Several effects have been described in human and animal intestines.
A Arimura, A Belai, A Dejda, A Ferencz, A Ferencz, A Ferencz, A Ferencz, A Ferencz, A Ferencz, A Ferencz, A Holmberg, A Kemeny, A Mittal, A Pirone, A Somogyvari-Vigh, A Szabo, A Tamas, AG Vinuesa, B Danyadi, B Gasz, B Jakab, B Kaminska, B Kaminska, B Racz, C Abad, C Abraham, C Brifault, CL He, D Brown, D Ganea, D Reglodi, D Reglodi, D Reglodi, D Reglodi, D Uchida, DA Wainwright, E Banki, E Banki, E Laszlo, E Laszlo, E Roth, EH Lee, G Horvath, G Horvath, G Maasz, H Ji, H Mori, H Ohtaki, J Godlewski, J Kun, J Nemeth, J Simpson, J Wojtkiewicz, K Elekes, K Miyamoto, K Nedvig, K Szabadfi, K Szabadfi, L Lenti, L Uyttebroek, LM Lindestrom, M Al-Qudah, M Delgado, M Delgado, M Delgado, M Ekelund, M Fujimiya, M Miampamba, M Rettenbacher, MB Watson, MG Zizzo, MJ Wu, MM Heimesaat, N Nemetz, O Masmoudi-Kouki, P Szakaly, P Szakaly, PS Leung, R Farre, S Gonkowski, S Gonkowski, S Rattan, S Shioda, SJ Rozzi, T Atlasz, T Nakamachi, T Seaborn, T Seki, Y Chen, Y Wada, YK Mao, YT Azuma, Z Lazar, Z Shen, Z Szanto   +94 more
core   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

Experimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers, Nile F. Banks, Emma R. Trachta, Morgan S. Wolf, Alexander C. Berry, Anna E. Stanhewicz, Lucas J. Carr, Bethany Barone Gibbs, Nathaniel D. M. Jenkins   +8 more
wiley   +1 more source

Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Signaling in The Prefrontal Cortex Modulates Cued Fear Learning, But Not Spatial Working Memory, in Female Rats [PDF]

, 2018
A genetic polymorphism within the gene encoding the pituitary adenylate cyclase- activating polypeptide (PACAP) receptor type I (PAC1R) has recently been associated with hyper-reactivity to threat-related cues in women, but not men, with post-traumatic ...
Gilmartin, Marieke R., Herbst, Matthew R., Kirry, Adam J., Maskeri, Michelle M., Poirier, Sarah E., Rothwell, Amy C., Twining, Robert C.   +6 more
core   +1 more source

Toll-Like Receptor 4 Modulates Small Intestine Neuromuscular Function through Nitrergic and Purinergic Pathways [PDF]

, 2017
Objective: Toll-like receptors (TLRs) play a pivotal role in the homeostatic microflora-host crosstalk. TLR4-mediated modulation of both motility and enteric neuronal survival has been reported mainly for colon with limited information on the role of ...
Cecilia Giulivi, Cecilia Giulivi, Eleonora Napoli, Francesca Galuppini, Genny Orso, Ilaria Marsilio, Isabella Lante, Maria Cecilia Giron, Massimo Rugge, Mona Roozfarakh, Silvia Cerantola, Silvia Cerantola, Valentina Caputi   +12 more
core   +3 more sources

The therapeutic role of exercise training during menopause for reducing vascular disease

Experimental Physiology, EarlyView.
Abstract Menopause marks a major milestone in female reproductive ageing. It is characterized by the cessation of ovarian function and a concomitant decline in hormones such as oestradiol. Subsequently, females undergoing menopausal transition experience a progressive increase in cardiovascular and cerebrovascular disease risk.
Conan L. H. Shing, Bert Bond, Kerrie L. Moreau, Jeff S. Coombes, Jenna L. Taylor   +4 more
wiley   +1 more source

Changes in the tissue concentrations of several neuropeptides in porcine intestines and intestine-innervating ganglia in the course of porcine proliferative enteropathy

Veterinární Medicína, 2018
Inflammatory processes are associated with changes in the interplay of different pro- and anti-inflammatory factors, including neuropeptides, in tissue.
Z. Pidsudko, J. Kaleczyc, J. Zmudzki, W. Sienkiewicz, M. Zalecki, M. Klimczuk, K. Wasowicz   +6 more
doaj   +1 more source

The effects of vasoactive intestinal peptide on human natural killer cell function.

Journal of Immunology, 1985
Vasoactive intestinal peptide (VIP) can be found at nerve endings in various tissues and has recently been shown to interact with human lymphocytes through an adenylate cyclase-linked receptor.
M. Rola-Pleszczynski, D. Bolduc, S. St.-Pierre   +2 more
semanticscholar   +1 more source

Partial enterectomy decreases somatostatin-binding sites in residual intestine of rabbits [PDF]

, 1988
Three weeks after partial enterectomy in the rabbit there was an increased somatostatin concentration and a decreased number of somatostatin-binding sites (without changes in the corresponding affinity values) in the cytosol of the residual intestinal ...
Arilla Ferreiro, Eduardo, Bodega Magro, Guillermo, Colás Escudero, Begoña, Prieto Villapún, Juan Carlos, Sanz, M.   +4 more
core   +1 more source

Increases in skin perfusion and blood oxygen in the non‐exercising human limbs during exercise in the heat: Implications for control of circulation

Experimental Physiology, EarlyView.
Abstract Blood flow in the inactive limb tissues and skin is widely thought to decline during incremental exercise to exhaustion due to augmented sympathoadrenal vasoconstrictor activity, but direct evidence to support this view is lacking. Here, we investigated the inactive‐forearm haemodynamic (Q̇forearm${\dot{Q}}_{\mathrm{forearm}}$) and oxygenation
Steven J. Trangmar, José González‐Alonso   +1 more
wiley   +1 more source