Results 101 to 110 of about 920,092 (279)

Clostridium difficile suppresses colonic vasoactive intestinal peptide associated with altered motility

Mediators of Inflammation, 1995
We investigated whether Clostridium difficile toxin alters colonic tissue levels of vasoactive intestinal peptide (VIP) at the expense of changes in colonic motility in the isolated perfused rabbit left colon.
A. Nassif, W. E. Longo, R. Sexe, M. Stratton, J. Standeven, A. M. Vernava, D. L. Kaminski   +6 more
doaj   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

ACUTE BUT NOT CHRONIC GASTRIC SODIUM ADMINISTRATION REGULATES VASOACTIVE-INTESTINAL-PEPTIDE METABOLISM BY THE LIVER

, 1991
We have shown previously that gastric sodium loading releases vasoactive intestinal peptide from the intestine and in rabbits on a low sodium diet it appears to decrease vasoactive intestinal peptide metabolism by the liver.
HAWLEY, CM, SHELLEY, S, DUGGAN, KA, MACDONALD, GJ   +3 more
core   +1 more source

Trajectory of the main GABAergic interneuron populations from early development to old age in the rat primary auditory cortex

Frontiers in Neuroanatomy, 2014
In both humans and rodents, decline in cognitive function is a hallmark of the aging process, the basis for this decrease has yet to be fully characterized.
Lydia eOuellet, Etienne ede Villers-Sidani   +1 more
doaj   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

The Journal of Physiology, EarlyView.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

Enzymatic synthesis of vasoactive intestinal peptide analogs by transglutaminase

, 1999
Vasoactive intestinal peptide is an amino acceptor and donor substrate for tissue transglutaminase (TGase) in vitro. This peptide contains a single glutamine residue, Gln(16) which was identified as the amino acceptor substrate.
MARINIELLO, LOREDANA, FERRANTI, PASQUALE, M. Carteni Farina, C. Esposito, A. Cozzolino, P. Stiuso, S. De Maria, S. Metafora   +7 more
core  

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

The Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires, Matheus Naia Fioretto, Marcel Rodrigues Ferreira, Isabelle Tenori Ribeiro, Luísa Annibal Barata, Flávia Alessandra Maciel, Lucas Sobrinho Lemos, Renato Mattos, Luiz Marcos Frediane Portela, Patrick Vieira de Souza, Luisa Correia Gomes, Gustavo Monezzi Cordeiro, Wellerson Rodrigo Scarano, Patrícia Aline Boer, Jose Antonio Rocha Gontijo, Luis Antonio Justulin   +15 more
wiley   +1 more source

Release of vasoactive intestinal polypeptide from the rat gastric fundus

, 1992
In the rat gastric fundus, vasoactive intestinal polypeptide (VIP) mimics the effects of inhibitory non-adrenergic, non-cholinergic (NANC) neurone activation.
D'Amato, M, Currò, D, Montuschi, P, Lefebvre, RomainGE338010003811850000-0003-2356-3714F3E60310-F0ED-11E1-A9DE-61C894A0A6B4, Ragazzoni, E, Ciabattoni, G   +5 more
core  

Vasoactive intestinal peptide releasing tumor which caused to chronic watery diarrhea and hypokalemia

, 2014
Watery diarrhea, hypokalemia and achlorhydria syndrome is a rare cause of chronic secretory diarrhea arising from a vasoactive intestinal peptide releasing tumor.
Emre Cecen, Kayi Eliacik, Kanik, Ali, Masallah Baran, Cayan, Ozlem, Tunc Ozdemir, Eliacik, Kayi, Baran, Masallah, Ali Kanik, Cecen, Emre, Ozdemir, Tunc, Ozlem Cayan, Mehmet Helvaci, Helvaci, Mehmet   +13 more
core   +1 more source

cGMP Signaling in Arterioles Revealed by FRET‐Based Real‐Time Measurement in Mice In Vivo

Acta Physiologica, Volume 242, Issue 11, November 2026.
ABSTRACT cGMP evokes arteriolar vasorelaxation and is generated in smooth muscle by the soluble guanylyl cyclase (sGC) stimulated by endothelial NO. Phosphodiesterases (PDEs) degrade cGMP and may contribute in diameter regulation. We examined arteriolar cGMP levels in real‐time in vivo upon NO and acetylcholine (ACh) and effects of PDE inhibition ...
Lukas Thiele, Kjestine Schmidt, Martin Thunemann, Andreas Friebe, Susanne Feil, Robert Feil, Cor de Wit   +6 more
wiley   +1 more source