Vasoconstrictor Responses to Vasopressor Agents in Human Pulmonary and Radial Arteries: An In Vitro Study [PDF]
Abstract Background: Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right heart ...
D. Currigan+4 more
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Vasorelaxant properties of norbormide, a selective vasoconstrictor agent for the rat microvasculature [PDF]
1. The effects of norbormide on the contractility of endothelium-deprived rat, guinea-pig, mouse, and human artery rings, and of freshly isolated smooth muscle cells of rat caudal artery were investigated. In addition, the effect of norbormide on intracellular calcium levels of A7r5 cells was evaluated. 2.
Sergio Bova+7 more
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Vasoconstrictor and Vasodilator Agents in Disseminated Intravascular Coagulation [PDF]
Modification of disseminated intravascular coagulation by vasculoactive agents has been evaluated in rabbits infused with thrombin, measuring the extent of renal capillary thrombosis, suppression of creatinine clearance and elevation of plasma creatinine and pl. haemoglobin.
A.N. Whitaker, Ian Bunce, Bryan C Sleigh
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Modification of the vasoconstrictor action of sympathomimetic agents by bretylium tosylate and tranylcypromine in man [PDF]
The vasoconstrictor actions of tyramine, methylamphetamine and ephedrine on the blood vessels of the human hand have been found to be potentiated by administration intra‐arterially of the adrenergic neurone blocking agent, bretylium tosylate. One mechanism suggested for the enhancement of vasoconstriction is that bretylium possesses monoamine oxidase ...
D. B. Frewin+2 more
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Responsiveness to Vasoconstrictor and Dilator Agents of Senescent Beagle Cerebral Arteries
With advancing age from 2 to 12 years, contractions of isolated beagle cerebral arteries mediated by histamine H1 and serotonin receptors increased, whereas those induced by noradrenaline and angiotensin II did not differ. Relaxations by vasodilator substances, such as prostaglandin (PG) I2, isoproterenol, adenosine and K+ (5 mM), and by stimulation of
Ikuko Shimizu+2 more
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Role of endothelium and nitric oxide in the in vitro response of equine colonic venous rings to vasoconstrictor agents. [PDF]
OBJECTIVE To determine in vitro contractile responses of equine colonic veins to various vasoconstrictor agents. ANIMALS Colonic veins collected from 8 adult horses.
Rustin M. Moore+3 more
semanticscholar +2 more sources
Modulation of temperature-induced tone by vasoconstrictor agents. [PDF]
One of the primary cardiovascular adjustments to hyperthermia is a sympathetically mediated increase in vascular resistance in the viscera. Nonneural factors such as a change in vascular tone or reactivity may also contribute to this response. Therefore,
M. Massett+3 more
semanticscholar +3 more sources
Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide. [PDF]
This study investigates the role of nitric oxide (NO) and the induction of a calcium-independent NO synthase (NOS) in development of vascular hyporeactivity to norepinephrine (NE) and vascular decompensation associated with hemorrhagic shock (HS) in the ...
C. Thiemermann+3 more
semanticscholar +2 more sources
Pharmacological reactivity of human epicardial coronary arteries: phasic and tonic responses to vasoconstrictor agents differentiated by nifedipine [PDF]
A. Stork, T. Cocks
semanticscholar +2 more sources
Local anaesthetic and vasoconstrictor agents used in ENT [PDF]
Ramindar S. Dhillon, James W. Fairley
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