Results 31 to 40 of about 1,523,943 (289)

Role of Norepinephrine and Vasopressin in Persistent Pulmonary Hypertension of the Newborn with Shock: A Case Series from a Tertiary Care Centre in Northern India [PDF]

Journal of Clinical and Diagnostic Research
Persistent Pulmonary Hypertension of the Newborn (PPHN) complicated by shock presents significant therapeutic challenges, particularly in resource-limited settings without access to inhaled Nitric Oxide (iNO) and Extracorporeal Membrane Oxygenation (ECMO)
Aayushi Joshi, Naini Puri, Syed Moiz Ahmed, Divya Mishra, Shantanu Shubham   +4 more
doaj   +1 more source

Dynamic inflammatory trajectories and 28-day mortality in patients in the intensive care unit: An exploratory observational study

Journal of Intensive Medicine
Background: Inflammatory dynamics profoundly influence outcomes in critically ill patients; however, the prognostic significance of early inflammatory trajectories remains unclear.
Xinyuan Ding, Shangzhong Chen, Lihong Zhu, Chengcheng Zheng, Hang Mou, Guolong Cai, Yanfei Shen   +6 more
doaj   +1 more source

Reduction of pressor response to vasoconstrictor agents by overexpression of catalase in mice [PDF]

American Journal of Hypertension, 2003
Hydrogen peroxide (H(2)O(2)) has been shown to induce vascular smooth muscle cell contraction in vitro. In this study, the effect of endogenously produced H(2)O(2) on blood pressure (BP) was examined using a transgenic mouse model (hCatTg(+/0)) in which catalase is overexpressed.The hCatTg(+/0) and wild-type mice received a bolus injection of ...
Hong, Yang, MingJian, Shi, Holly, VanRemmen, XinLian, Chen, Jan, Vijg, Arlan, Richardson, ZhongMao, Guo   +6 more
openaire   +2 more sources

Pharmacological Potential of Endothelin Receptors Agonists and Antagonists

Acta Medica, 2005
Endothelins are potent predominantly vasoconstricting agents that act as local autocrine and paracrine mediators. Endothelin-1 is the most potent and sustained vasoconstrictor and pressor substance yet identified.
Jiří Patočka, Vladimír Měrka, Vratislav Hrdina, Radomír Hrdina   +3 more
doaj   +1 more source

The evolution of mean arterial pressure in critically ill patients on vasopressors before and during a trial comparing a specific mean arterial pressure target to usual care

BMC Anesthesiology, 2022
Background In randomized clinical controlled trials, the choice of usual care as the comparator may be associated with better clinician uptake of the study protocol and lead to more generalizable results. However, if care processes evolve to resemble the
Marie-Hélène Masse, Neill K. J. Adhikari, Xavier Théroux, Marie-Claude Battista, Frédérick D’Aragon, Ruxandra Pinto, Alan Cohen, Michaël Mayette, Charles St-Arnaud, Michelle Kho, Michaël Chassé, Martine Lebrasseur, Irene Watpool, Rebecca Porteous, M. Elizabeth Wilcox, François Lamontagne   +15 more
doaj   +1 more source

Severe Burn Injury Alters Expression of Adrenergic Receptor Transcripts in a Rodent Model

European Burn Journal
Background: Norepinephrine is commonly used during acute burn resuscitation to maintain adequate perfusion pressure. However, its effects, together with the burn-induced catecholamine surge, on arterial α1-adrenergic receptors (α1-AR) remain unclear ...
Kristine Knappskog, Julia Kleinhapl, Titas Gladkauskas, Siren Fromreide, Dagrun Slettebø Daltveit, Jake E. Lowry, Per Morten Knappskog, Henning Onarheim, Anne Berit Guttormsen, Daniela Elena Costea, Amina El Ayadi, Juquan Song, Steven E. Wolf, Stian Kreken Almeland   +13 more
doaj   +1 more source

Intraoperative vasopressor use and early postoperative acute kidney injury in elderly patients undergoing elective noncardiac surgery

Renal Failure, 2022
Background Intraoperative hypotension is a risk factor for postoperative acute kidney injury (AKI). Elderly patients are susceptible due to reduced responses to acute hemodynamic changes.Aims Determine the association between hypotension identified from ...
Dilshan Ariyarathna, Ajinkya Bhonsle, Joseph Nim, Colin K. L. Huang, Gabriella H. Wong, Nicholle Sim, Joy Hong, Kirrolos Nan, Andy K. H. Lim   +8 more
doaj   +1 more source

Enhanced vascular reactivity to various vasoconstrictor agents following pinealectomy in the rat: role of melatonin

, 1980
The mesenteric vascular bed preparation of control and pinealectomized (PX) male Wistar rats was used to examine vascular reactivity to two concentrations each of norepinephrine, serotonin, angiotensin, and potassium.
Stephen C. Cunnane, Masatsugu Oka, Mehar S. Manku, David F. Horrobin   +3 more
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida, Gisela Cristiane Miyamoto, Daniel da Costa Torres, Ian Setubal Reis Chaves, Jonas do Carmo Paschoalin, Braúlio Lima Nascimento, Luciana Dias Chiavegato   +6 more
wiley   +1 more source

Tongue necrosis as a complication of vasoconstrictor agents in the intensive care setting [PDF]

Internal and Emergency Medicine, 2010
The tongue is well irrigated by the lingual and submandibular arteries along with numerous collaterals that are invariably present. This rich vascular supply makes tongue necrosis exceptional. Tongue necrosis has been reported in giant cell arteritis, Wegener’s granulomatosis, malignant tumors, previous radiation to the neck, intraarterial injections ...
Noordally, Sheik Oaleed, Gottignies, Philippe, Devriendt, Jacques, Sohawon, Schoeb, Duttmann, Ruth   +4 more
openaire   +3 more sources