Results 121 to 130 of about 47,711 (290)

VEGF inhibitor‐induced vascular dysfunction involves redox‐sensitive PARP activation and SIRT1 disruption

Experimental Physiology, EarlyView.
Abstract Vascular endothelial growth factor receptor (VEGFR) inhibitors are effective antiangiogenic agents used in cancer therapy. However, they are associated with cardiovascular disease, including hypertension and vascular dysfunction. The molecular mechanisms underlying these cardiovascular toxicities are unclear, but oxidative stress might be ...
Karla B. Neves, Rheure Alves‐Lopes, Augusto C. Montezano, Rhian M. Touyz   +3 more
wiley   +1 more source

Sex differences in dynamic cerebral autoregulation responses to resistance and endurance training in humans

Experimental Physiology, EarlyView.
Abstract Exercise maintains brain health and reduces the risk of cerebrovascular diseases, such as stroke and dementia. The benefits of different ‘modalities’ of exercise on male and female cerebral autoregulation are unclear. In this study, we compared adaptations in dynamic cerebral autoregulation (dCA) during spontaneous and forced oscillations in ...
Hannah J. Thomas, Channa E. Marsh, Leanne Lester, Louise H. Naylor, Kurt J. Smith, Daniel J. Green   +5 more
wiley   +1 more source

Two neural mechanisms for respiration-induced cutaneous vasodilatation in humans? [PDF]

, 1998
1. In humans, a deep breath is known to induce cutaneous vasoconstriction in the warm state, and vasodilatation in the cold state. To investigate whether vasodilatation in the cold state is related to reduction of sympathetic vasoconstrictor nerve ...
Kienbaum, P, Karlsson, T, Elam, M, Gazelius, B, Wallin, Gunnar B,, Båtelsson, K   +5 more
core  

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Myocardial Perfusion Defects in Hypertrophic Cardiomyopathy Mutation Carriers

Journal of the American Heart Association, EarlyView., 2021
Background Impaired myocardial blood flow (MBF) in the absence of epicardial coronary disease is a feature of hypertrophic cardiomyopathy (HCM). Although most evident in hypertrophied or scarred segments, reduced MBF can occur in apparently normal segments.
Rebecca K. Hughes, Claudia Camaioni, João B. Augusto, Kristopher Knott, Ellie Quinn, Gabriella Captur, Andreas Seraphim, George Joy, Petros Syrris, Perry M. Elliott, Saidi Mohiddin, Peter Kellman, Hui Xue, Luis R. Lopes, James C. Moon   +14 more
wiley   +1 more source

Sympathetic vasodilatation in human skin

The Journal of Physiology, 2003
In the decades preceding and following the Second World War, knowledge about the human peripheral circulation increased rapidly. A number of factors contributed. One was the increasing interest in the field and the analytical techniques used initially by Sir Thomas Lewis at the Department of Medicine, University College London, and spread by some of ...
openaire   +3 more sources

Blistering barnacles: Space physiology in The Adventures of Tintin

Experimental Physiology, EarlyView.
Jacob P. Hartmann, Mathis B. Mottelson, Rasmus H. Dahl, Ronni R. Plovsing, Ronan M. G. Berg   +4 more
wiley   +1 more source

Sex differences in the prefrontal cortex and muscle oxygenation during exercise until exhaustion in endurance‐trained individuals

Experimental Physiology, EarlyView.
Abstract figure legend During cardiopulmonary exercise testing, the decline in oxygenation in the prefrontal cortex of women is striking. This crucial brain area is directly involved in planning motor tasks. The decline is particularly pronounced at higher exercise intensities, especially after reaching the respiratory compensation point or anaerobic ...
Daniel Ramos‐López, Raúl Caulier‐Cisterna, Benjamín Díaz‐Ortiz, Cristóbal Baumann‐Biancani, Kamilo Hunger‐Abbott, Matías Herrera‐Matas, Andrés Vega‐Moraga, Vitor A. Lira, Maximiliano Espinosa‐Ramírez, Karol Ramírez‐Parada, Luigi Gabrielli‐Nervi, Hugo E. Verdejo, Felipe Contreras‐Briceño   +12 more
wiley   +1 more source

Effects of Intrauterine Isoproterenol Administration on Ovarian Follicular Development in Cows

Veterinary Medicine and Science
Background Isoproterenol (ISO) is a nonselective beta‐adrenergic receptor agonist known for its vasodilatory effects. This experiment aims to investigate whether intrauterine ISO administration could alter vascular indices and follicular development in ...
Vefa Tohumcu, Mehmet Cengiz, A. Hayirli, K. Altinkaynak, Emre Arslanbas, Alper Yasin Ciplak, S. Aydın, Omercan Alat   +7 more
doaj   +1 more source

Levobupivacaine induces vasodilatation, but not vasoconstriction, in rat mesenteric artery

Revista de Odontologia da UNESP
Introduction Levobupivacaine (LEVO) can replace analgesia because it exhibits low toxicity and causes minor vasoconstriction, enabling its use in patients in whom vasoconstrictors are contraindicated.
Liciane dos Santos MENEZES, Liane Maciel de Almeida SOUZA, Márcio Roberto Viana dos SANTOS, Patrícia Santos Cunha MENDONÇA, Ítalo José Alves MOREIRA, Allan Carlos Araújo de OLIVEIRA   +5 more
doaj   +1 more source