Results 41 to 50 of about 86,075 (269)

Triptans and CGRP blockade - impact on the cranial vasculature [PDF]

open access: yes, 2017
The trigeminovascular system plays a key role in the pathophysiology of migraine. The activation of the trigeminovascular system causes release of various neurotransmitters and neuropeptides, including serotonin and calcitonin gene-related peptide ...
Alejandro Labastida-Ramírez   +9 more
core   +3 more sources

Antithrombotic effect of epigallocatechin gallate on the patency of arterial microvascular anastomoses

open access: yesArchives of Plastic Surgery, 2019
Background Microvascular anastomosis patency is adversely affected by local and systemic factors. Impaired intimal recovery and endothelial mechanisms promoting thrombus formation at the anastomotic site are common etiological factors of reduced ...
Murat İğde   +5 more
doaj   +1 more source

Coronary vasodilatation following diazepam (Valium) [PDF]

open access: yesBritish Journal of Pharmacology, 1970
Summary . The effects of diazepam (Valium) on coronary and systemic vascular resistance were studied in anaesthetized dogs on cardiopulmonary bypass under conditions of constant heart rate and aortic pressure. . Pharmacological doses of diazepam uniformly produced coronary vasodilation lasting 30 min; systemic vascular resistance also decreased, but to
R M, Abel, R L, Reis, R N, Staroscik
openaire   +2 more sources

Replacing the Transfusion of 1-2 Units of Blood with Plasma Expanders that Increase Oxygen Delivery Capacity: Evidence from Experimental Studies. [PDF]

open access: yes, 2014
At least a third of the blood supply in the world is used to transfuse 1-2 units of packed red blood cells for each intervention and most clinical trials of blood substitutes have been carried out at this level of oxygen carrying capacity (OCC ...
Acharya, Seetharama A   +7 more
core   +3 more sources

Synthetic Vasopressin and Oxytocin Analogs and Their Potential Use in Hemorrhagic, Traumatic and Septic Shock: A Personal Perspective [PDF]

open access: yes, 2017
As one of us has stated many years ago, “shock is a significant and sustained loss of effective circulating blood volume. It will eventuate in hypoperfusion of critical peripheral tissues, thus leading to a deficit in transcapillary exchange function in ...
Altura BM   +3 more
core   +1 more source

FLOW-MEDIATED VASODILATATION

open access: yesThe Professional Medical Journal, 2018
Objective: To assess whether flow-mediated dilatation (FMD) affectedcardiovascular (CV) parameters after consuming fructose or sucralose. Data source: Finometer.Design of study: Randomized, cross-over, single-blind design. Setting: School of biomedicalsciences, University of Nottingham, UK. Period: July, 2009.
Muhammad Qasim Memon, Ian A Macdonald
openaire   +2 more sources

The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]

open access: yes, 2013
Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Alex Dyson   +23 more
core   +1 more source

Radial capacity and hemodynamics evaluation in vitro and implantable feasibility validation in vivo of thinner bioresorbable polymer vascular stents

open access: yesBMEMat, EarlyView.
A series of in vitro experiments, numerical simulations and in vivo experiments were conducted to jointly evaluate the effects of different thicknesses of bioabsorbable polymer vascular stents on their radial capacity, hemodynamics and in vivo outcomes.
Chong Chen   +9 more
wiley   +1 more source

Apixaban Enhances Vasodilatation Mediated by Protease-Activated Receptor 2 in Isolated Rat Arteries

open access: yesFrontiers in Pharmacology, 2017
Apixaban (APX) is a direct inhibitor of factor X (FXa) approved for prophylaxis and treatment of deep venous thrombosis and atrial fibrillation. Because FXa activates protease-activated receptor 2 (PAR-2) in endothelium and vascular smooth muscle ...
Ambra Villari   +4 more
doaj   +1 more source

Stroke and migraine is there a possible comorbidity? [PDF]

open access: yes, 2016
The association between migraine and stroke is still a dilemma for neurologists. Migraine is associated with an increased stroke risk and it is considered an independent risk factor for ischaemic stroke in a particular subgroup of patients.
Del Balzo, Francesca   +7 more
core   +2 more sources

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