Results 1 to 10 of about 101,746 (297)

Dilatory effects and safety of a polyphenol-rich extract of Steganotaenia araliacea Hochst (Apiaceae) on rat aortic rings [PDF]

open access: yesFrontiers in Pharmacology
BackgroundHypertension is a major global public health concern. Many communities in developing countries still rely on medicinal plants as a source of primary healthcare for treatment of hypertension instead of conventional antihypertensive drugs ...
Newton Simfukwe   +4 more
doaj   +2 more sources

Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats

open access: yesFrontiers in Pharmacology, 2022
Lotus (Nelumbo nucifera) leaves are widely used for both edible and medicinal applications. For its further utilization, we studied the vasodilatory activity of lotus leaf extract for the first time.
Hao Deng   +9 more
doaj   +1 more source

Acute effects of exercise with blood flow restriction on endothelial function in healthy young and older populations: a systematic review

open access: yesGeriatrics, Gerontology and Aging, 2023
The objective of this review is to identify the acute effects of blood flow restriction (BFR) with vs without exercise on endothelial function in healthy individuals and the changes in endothelial function in young and older adults following different ...
Gustavo Gonçalves Cardozo   +6 more
doaj   +1 more source

Vanillin Induces Relaxation in Rat Mesenteric Resistance Arteries by Inhibiting Extracellular Ca2+ Influx

open access: yesMolecules, 2022
Vanillin is a phenolic aldehyde, which is found in plant species of the Vanilla genus. Although recent studies have suggested that vanillin has various beneficial properties, the effect of vanillin on blood vessels has not been studied well.
Sooyeon Choi   +5 more
doaj   +1 more source

Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta [PDF]

open access: yesKorean Journal of Anesthesiology, 2013
BackgroundIntravenous lipid emulsion has been used to treat systemic toxicity of local anesthetics. The goals of this in vitro study were to determine the ability of two lipid emulsions (Intralipid® and Lipofundin® MCT/LCT) to reverse toxic dose local ...
Seong-Ho Ok   +7 more
doaj   +1 more source

Targeting Soluble Guanylyl Cyclase during Ischemia and Reperfusion

open access: yesCells, 2023
Ischemia and reperfusion (IR) damage organs and contribute to many disease states. Few effective treatments exist that attenuate IR injury. The augmentation of nitric oxide (NO) signaling remains a promising therapeutic target for IR injury.
Eric H. Mace   +3 more
doaj   +1 more source

Acute effects of strength exercise with blood flow restriction on the arterial resistance index

open access: yesRevista da Educação Física, 2020
The present study aimed to evaluate the acute behavior of the brachial artery resistance index (BARI) and popliteal artery resistance index (PARI) in response to low intensity strength exercises involving small (SMG) and large muscle groups (LMG ...
Sabrina Lencina Bonorino   +5 more
doaj   +1 more source

Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction

open access: yesFrontiers in Physiology, 2021
The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of the intestinal tract, as well as by bacterial enzymes in the ...
Tilman Sauerbruch   +3 more
doaj   +1 more source

Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway

open access: yesFrontiers in Pharmacology, 2022
Modified Lvdou Gancao decoction (MLG), a traditional Chinese medicine formula, has been put into clinical use to treat the diseases of the digestive system for a long run, showing great faculty in gastric protection and anti-inflammatory, whereas its ...
Lei Xie   +9 more
doaj   +1 more source

Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

open access: yesFrontiers in Physiology, 2020
Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure.
Asim B. Dey   +17 more
doaj   +1 more source

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