Results 1 to 10 of about 83,032 (294)

Study of vasodilation processes

Journal of Education, Health and Sport, 2019
To date, the key role of endothelial dysfunction in the occurrence and progression of diabetes mellitus and diabetic retinopathy has been proven. The study was performed on white Wistar rats weighing 180-200 g.
Ya. V. Sirman, I. V. Savytskyi
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Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction

Frontiers in Physiology, 2021
The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of the intestinal tract, as well as by bacterial enzymes in the ...
Tilman Sauerbruch, Martin Hennenberg, Jonel Trebicka, Ulrich Beuers   +3 more
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The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease

Frontiers in Molecular Neuroscience, 2023
IntroductionThe disintegrin and metalloproteinase 17 (ADAM17) exhibits α-secretase activity, whereby it can prevent the production of neurotoxic amyloid precursor protein-α (APP).
Yanna Tian, Katie Anne Fopiano, Vadym Buncha, Liwei Lang, Hayden A. Suggs, Rongrong Wang, R. Daniel Rudic, Jessica A. Filosa, Zsolt Bagi   +8 more
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Acute effects of exercise with blood flow restriction on endothelial function in healthy young and older populations: a systematic review

Geriatrics, Gerontology and Aging, 2023
The objective of this review is to identify the acute effects of blood flow restriction (BFR) with vs without exercise on endothelial function in healthy individuals and the changes in endothelial function in young and older adults following different ...
Gustavo Gonçalves Cardozo, Karynne Grutter Lopes, Daniel Alexandre Bottino, Maria das Graças Coelho de Souza, Eliete Bouskela, Paulo Farinatti, Ricardo Brandão de Oliveira   +6 more
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Shenfu Injection Promotes Vasodilation by Enhancing eNOS Activity Through the PI3K/Akt Signaling Pathway In Vitro

Frontiers in Pharmacology, 2020
Vasomotor dysfunction is one of the key pathological aspects of shock and heart failure (HF). Shenfu injection (SFI) has been widely used for the treatment of shock and HF in China.
Jinqiang Zhu, Jinqiang Zhu, Wanshan Song, Shixin Xu, Shixin Xu, Yan Ma, Baoyu Wei, Baoyu Wei, Hongwu Wang, Shengyu Hua, Shengyu Hua, Shengyu Hua   +11 more
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Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

Frontiers in Cardiovascular Medicine, 2022
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva, Christopher J. Hatch, Megan T. Chu, Trevor R. Cardinal   +3 more
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Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats

Frontiers in Pharmacology, 2022
Lotus (Nelumbo nucifera) leaves are widely used for both edible and medicinal applications. For its further utilization, we studied the vasodilatory activity of lotus leaf extract for the first time.
Hao Deng, Qian Xu, Xiao-Tong Sang, Xing Huang, Li-Li Jin, Fen-Er Chen, Fen-Er Chen, Qing-Kun Shen, Zhe-Shan Quan, Li-Hua Cao   +9 more
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Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway

Frontiers in Pharmacology, 2022
Modified Lvdou Gancao decoction (MLG), a traditional Chinese medicine formula, has been put into clinical use to treat the diseases of the digestive system for a long run, showing great faculty in gastric protection and anti-inflammatory, whereas its ...
Lei Xie, Minyi Luo, Junlin Li, Wenguan Huang, Guangjun Tian, Xiuyun Chen, Ying Ai, Yan Zhang, Haolan He, Jinyang He   +9 more
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Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Frontiers in Physiology, 2020
Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure.
Asim B. Dey, Sherif Khedr, Sherif Khedr, James Bean, Leah L. Porras, Tamika D. Meredith, Francis S. Willard, Joseph V. Hass, Xin Zhou, Maia Terashvili, Cynthia D. Jesudason, Kevin M. Ruley, Michael R. Wiley, Mark Kowala, Simon J. Atkinson, Alexander Staruschenko, Alexander Staruschenko, Mark D. Rekhter   +17 more
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Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta

Molecules, 2020
The infusion of the desertic plant Nolana ramosissima I.M. Johnst showed vascular smooth muscle relaxation in rat aorta and the presence of several phenolic compounds, which were detected by high resolution UHPLC-Orbitrap-HESI-MS.
Fredi Cifuentes, Javier Palacios, Jorge Bórquez, Adrián Paredes, Claudio Parra, Alejandra Bravo, Mario J. Simirgiotis   +6 more
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