Results 1 to 10 of about 9,403 (112)

Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway

Frontiers in Pharmacology, 2022
Modified Lvdou Gancao decoction (MLG), a traditional Chinese medicine formula, has been put into clinical use to treat the diseases of the digestive system for a long run, showing great faculty in gastric protection and anti-inflammatory, whereas its ...
Lei Xie, Minyi Luo, Junlin Li, Wenguan Huang, Guangjun Tian, Xiuyun Chen, Ying Ai, Yan Zhang, Haolan He, Jinyang He   +9 more
doaj   +1 more source

Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats

Frontiers in Pharmacology, 2022
Lotus (Nelumbo nucifera) leaves are widely used for both edible and medicinal applications. For its further utilization, we studied the vasodilatory activity of lotus leaf extract for the first time.
Hao Deng, Qian Xu, Xiao-Tong Sang, Xing Huang, Li-Li Jin, Fen-Er Chen, Fen-Er Chen, Qing-Kun Shen, Zhe-Shan Quan, Li-Hua Cao   +9 more
doaj   +1 more source

Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease

Pulmonary Circulation, 2022
Pulmonary veno‐occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH) is a rare subtype of pulmonary hypertension with dismal prognosis.
Junichi Nakamura, Ichizo Tsujino, Hideki Shima, Toshitaka Nakaya, Ayako Sugimoto, Takahiro Sato, Taku Watanabe, Hiroshi Ohira, Masaru Suzuki, Satonori Tsuneta, Ryo Hisada, Masaru Kato, Satoshi Konno   +12 more
doaj   +1 more source

Embedded Deep Regularized Block HSIC Thermomics for Early Diagnosis of Breast Cancer [PDF]

IEEE Transactions on Instrumentation and Measurement 2021, 2021
Thermography has been used extensively as a complementary diagnostic tool in breast cancer detection. Among thermographic methods matrix factorization (MF) techniques show an unequivocal capability to detect thermal patterns corresponding to vasodilation in cancer cases.
arxiv   +1 more source

Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta

Molecules, 2020
The infusion of the desertic plant Nolana ramosissima I.M. Johnst showed vascular smooth muscle relaxation in rat aorta and the presence of several phenolic compounds, which were detected by high resolution UHPLC-Orbitrap-HESI-MS.
Fredi Cifuentes, Javier Palacios, Jorge Bórquez, Adrián Paredes, Claudio Parra, Alejandra Bravo, Mario J. Simirgiotis   +6 more
doaj   +1 more source

Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

Frontiers in Cardiovascular Medicine, 2022
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva, Christopher J. Hatch, Megan T. Chu, Trevor R. Cardinal   +3 more
doaj   +1 more source

Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction

Frontiers in Physiology, 2021
The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of the intestinal tract, as well as by bacterial enzymes in the ...
Tilman Sauerbruch, Martin Hennenberg, Jonel Trebicka, Ulrich Beuers   +3 more
doaj   +1 more source

Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Frontiers in Physiology, 2020
Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure.
Asim B. Dey, Sherif Khedr, Sherif Khedr, James Bean, Leah L. Porras, Tamika D. Meredith, Francis S. Willard, Joseph V. Hass, Xin Zhou, Maia Terashvili, Cynthia D. Jesudason, Kevin M. Ruley, Michael R. Wiley, Mark Kowala, Simon J. Atkinson, Alexander Staruschenko, Alexander Staruschenko, Mark D. Rekhter   +17 more
doaj   +1 more source

The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease

Frontiers in Molecular Neuroscience, 2023
IntroductionThe disintegrin and metalloproteinase 17 (ADAM17) exhibits α-secretase activity, whereby it can prevent the production of neurotoxic amyloid precursor protein-α (APP).
Yanna Tian, Katie Anne Fopiano, Vadym Buncha, Liwei Lang, Hayden A. Suggs, Rongrong Wang, R. Daniel Rudic, Jessica A. Filosa, Zsolt Bagi   +8 more
doaj   +1 more source

Acute effects of exercise with blood flow restriction on endothelial function in healthy young and older populations: a systematic review

Geriatrics, Gerontology and Aging, 2023
The objective of this review is to identify the acute effects of blood flow restriction (BFR) with vs without exercise on endothelial function in healthy individuals and the changes in endothelial function in young and older adults following different ...
Gustavo Gonçalves Cardozo, Karynne Grutter Lopes, Daniel Alexandre Bottino, Maria das Graças Coelho de Souza, Eliete Bouskela, Paulo Farinatti, Ricardo Brandão de Oliveira   +6 more
doaj   +1 more source