Results 31 to 40 of about 103,739 (262)

Mitochondrial Dysfunction Unravels the Potential Molecular Link Between Night Shift Work‐Related Circadian Disruption and Elevated Blood Pressure in Human and Mouse Models

open access: yesAdvanced Science, EarlyView.
This diagram illustrates that night shift work disrupts circadian clock genes (like CLOCK, BMAL1) in both humans and mice. This disruption leads to mitochondrial dysfunction (imbalanced fusion/fission proteins) and increased oxidative stress, which is identified as the primary mechanism ultimately causing elevated blood pressure.
Zhaoqiang Jiang   +16 more
wiley   +1 more source

Dissociation between vasodilation and Leishmania infection-enhancing effects of sand fly saliva and maxadilan

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
In this study, the ability of maxadilan and Lutzomyia longipalpis salivary gland lysate to enhance the infection of CBA mice by Leishmania major and of BALB/c mice by L. braziliensis was tested.
Fábio Castro-Sousa   +5 more
doaj   +1 more source

Zofenopril: Blood pressure control and cardio-protection

open access: yesCardiology Journal, 2022
Current hypertension guidelines suggest various strategies to reduce blood pressure levels, thereby reducing cardiovascular events: combinations of drugs with different mechanisms of action, such as an angiotensin converting enzyme inhibitors (ACEIs) and
Claudio Borghi   +3 more
doaj   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Vasodilation increases pulse pressure variation, mimicking hypovolemic status in rabbits

open access: yesClinics, 2010
OBJECTIVE: To test the hypothesis that pulse pressure respiratory variation (PPV) amplification, observed in hypovolemia, can also be observed during sodium nitroprusside (SNP)-induced vasodilation.
Glauco A Westphal   +5 more
doaj   +1 more source

NIR‐II‐Trackable LYTACs Phyto‐Nanotheranostics for Source‐Microenvironment Dual‐Track ROS Regulation in Acute Gouty Arthritis

open access: yesAdvanced Science, EarlyView.
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang   +15 more
wiley   +1 more source

Study of vasodilation processes

open access: yesJournal of Education, Health and Sport, 2019
To date, the key role of endothelial dysfunction in the occurrence and progression of diabetes mellitus and diabetic retinopathy has been proven. The study was performed on white Wistar rats weighing 180-200 g.
Ya. V. Sirman, I. V. Savytskyi
doaj   +1 more source

Hydrogen Sulfide-Induced Vasodilation: The Involvement of Vascular Potassium Channels

open access: yesFrontiers in Pharmacology, 2022
Hydrogen sulfide (H2S) has been highlighted as an important gasotransmitter in mammals. A growing number of studies have indicated that H2S plays a key role in the pathophysiology of vascular diseases and physiological vascular homeostasis. Alteration in
Xiao-Yu Liu   +2 more
doaj   +1 more source

Enhancing Blood Circulation With Epsilon‐Near‐Zero (ENZ) Materials via the Far‐Infrared Window of Human Skin

open access: yesAdvanced Science, EarlyView.
Epsilon‐near‐zero (ENZ) silicon carbide enables a selective far‐infrared emitter spectrally aligned with the human skin window around 10 µm for wavelength‐matched thermal therapy. In 25 within‐subject trials (50 hands) monitored by laser speckle contrast imaging, SiC increases blood perfusion by 30.2% versus a broadband graphite emitter while ...
Wen‐Teng Yao   +3 more
wiley   +1 more source

The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects

open access: yesPharmaceuticals, 2021
GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in the control of cardiovascular functions, including heart rate, contractility, vascular tone, as well as blood pressure.
Magdalena Kotańska   +7 more
doaj   +1 more source

Home - About - Disclaimer - Privacy