Results 91 to 100 of about 204,625 (386)
Journal of NutriLife, 2013 Dietary nitrate, from beetroot, has been reported to lower blood pressure (BP) by the sequential reduction of nitrate to nitrite and further to NO in the circulation. However, the impact of beetroot on microvascular vasodilation and arterial stiffness is
D. Hobbs +7 more
semanticscholar +1 more source
Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury
Advanced Science, EarlyView.The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He +11 more
wiley +1 more source
Endothelial dysfunction and inflammation in asymptomatic proteinuria [PDF]
, 2003 Background. Proteinuria is associated with vascular risk and a systemic increase in vascular permeability. Endothelial dysfunction occurs early in atherosclerosis and modulates vascular permeability. Vascular risk and chronic inflammation are associated.
Adams +67 more
core +1 more source
American Journal of Hematology, EarlyView.Key challenges in diagnosing anemia in high‐altitude populations include variability in hemoglobin (Hb) concentration, associated pathological conditions, altitude‐induced plasma volume changes, and environmental factors such as contamination and nutrition.
Ayoub Boulares +11 more
wiley +1 more source
Mechanisms of rapid vasodilation after a brief contraction in human skeletal muscle.
American Journal of Physiology. Heart and Circulatory Physiology, 2013 A monophasic increase in skeletal muscle blood flow is observed after a brief single forearm contraction in humans, yet the underlying vascular signaling pathways remain largely undetermined.
Anne R Crecelius +4 more
semanticscholar +1 more source
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
Vasorelaxation Induced by a New Naphthoquinone-Oxime is Mediated by NO-sGC-cGMP Pathway
Molecules, 2014 It has been established that oximes cause endothelium-independent relaxation in blood vessels. In the present study, the cardiovascular effects of the new oxime 3-hydroxy-4–(hydroxyimino)-2-(3-methylbut-2-enylnaphtalen-1(4H)-one (Oxime S1) derived from
Bruna P. V. Dantas +12 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The aim of this study was to improve the long‐term LL‐37 mouse model and compare the disease manifestations and pathophysiology of short‐term and long‐term LL‐37‐induced rosacea‐like models. The results show that the long‐term LL‐37 induced mouse model provides a practical animal model for further study of the pathological mechanism of severe rosacea ...
Yiling Wu +10 more
wiley +1 more source
International Journal of Nanomedicine, 2017 Teba Mohamed,1,* Sabine Matou-Nasri,2,* Asima Farooq,3 Debra Whitehead,3 May Azzawi1 1School of Healthcare Science, Faculty of Science and Engineering, Manchester Metropolitan University, Manchester, UK; 2Cell and Gene Therapy Group, Medical Genomics ...
Mohamed T +4 more
doaj
Phytochemical Study of Tapirira guianensis Leaves Guided by Vasodilatory and Antioxidant Activities
Molecules, 2017 The aim of this research was to perform a phytochemical study of the methanol leaves extract of T. guianensis (MET) guided by vasodilatory and antioxidant activities. The chemical profile of MET and the ethyl acetate fraction (EA fraction) was determined
Amélia M. G. Rodrigues +9 more
doaj +1 more source