Results 181 to 190 of about 9,502 (211)
British Journal of Pharmacology, EarlyView.Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley +1 more source
Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension. [PDF]
, 1995 Christoph Stein +5 more
openalex +1 more source
Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Vasoreactivity of pulmonary arteries regulates blood flow through the lungs. Excessive constriction of these vessels contributes to pulmonary arterial hypertension (PAH), a progressive and incurable condition, resulting in right heart failure.
Adam L. Fellows +8 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Sex‐dependent vascular effects of transient receptor potential (TRP) channels and sex dimorphism in migraine are not yet fully characterized. We investigated the differential vasoactive effects of TRP ankyrin 1 (TRPA1), TRP melastatin 3 (TRPM3) and TRP vanilloid 1 (TRPV1) channels, their pharmacological mechanism(s), and
Eduardo Rivera‐Mancilla +7 more
wiley +1 more source
Vitamin D deficiency induces erectile dysfunction: Role of superoxide and Slpi
British Journal of Pharmacology, EarlyView.Background and Purpose Epidemiological studies suggest a relationship between vitamin D deficiency and erectile dysfunction (ED). We hypothesized that vitamin D deficiency or vitamin D receptor (VDR) knockout causes ED and analysed the underlying molecular mechanisms.
Miguel A. Olivencia +14 more
wiley +1 more source
Arterial vasodilation is not the cause of increased cardiac output in cirrhosis
, 1992 Frederick W. Lewis +2 more
openalex +1 more source
Dental Implant Therapy in Patients With Autoimmune Diseases: A Scoping Review
Clinical Oral Implants Research, EarlyView.ABSTRACT Objectives The aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes. Material and Methods An electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024.
Emil Hyldahl +2 more
wiley +1 more source
Contact Urticaria and Related Conditions: Clinical Review
Contact Dermatitis, EarlyView.ABSTRACT Contact urticaria (CoU) is an immediate contact reaction occurring within minutes to an hour after exposure to specific proteins or chemicals. CoU is categorised into non‐immunologic (NI‐CoU) and immunologic (I‐CoU) types, with I‐CoU potentially leading to anaphylaxis. Both forms of CoU can be associated with protein contact dermatitis and the
Mojca Bizjak +15 more
wiley +1 more source