Abstract Objectives/Background Chronic migraine is a debilitating neurological disorder characterized by central sensitization and impaired brainstem habituation. OnabotulinumtoxinA is an established prophylactic treatment for chronic migraine, yet its effects on central trigeminal sensory processing remain incompletely understood.
Gerlinde Freimark +8 more
wiley +1 more source
Maternal Gestational Diabetes Impairs Fetoplacental Insulin-Induced Vasodilation via AKT/eNOS Pathway and Reduces Placental Efficiency. [PDF]
Hengst CM +9 more
europepmc +1 more source
Nitric oxide, vasodilation and the red blood cell
Michael J. Simmonds +2 more
semanticscholar +1 more source
TRPM3 activation causes CGRP release in trigeminal neurons: Implications for migraine mechanisms
Abstract Background The transient receptor potential melastatin 3 (TRPM3) ion channel has been implicated in sensory modulation and pain transmission and may contribute to migraine pathophysiology through calcitonin gene‐related peptide (CGRP) release in the trigeminovascular system. This study aimed to investigate TRPM3 activation and its role in CGRP
Philip V. Reducha +9 more
wiley +1 more source
Beta-3 Adrenoreceptor Agonist Mirabegron Improves Right Ventricular Function in a Rat Monocrotaline-Induced Pulmonary Hypertension Model. [PDF]
Mendes-Ferreira P +13 more
europepmc +1 more source
Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats [PDF]
Peter Schmid +6 more
openalex +1 more source
Elevated circulating free fatty acid levels impair endothelium-dependent vasodilation.
H. Steinberg +7 more
semanticscholar +1 more source
In children with biliary atresia (BA), breath‐holding during liver and spleen stiffness (LS and SS) measurement is often difficult, raising concerns about measurement reliability in the awake state. We investigated whether performing LS and SS measurements under general anesthesia—when brief ventilation pauses are possible—could improve diagnostic ...
Shinya Yokoyama +11 more
wiley +1 more source
Radiation- and age-related vascular dysfunction as an early indicator of cardiovascular risk: a long-term study in the ApoE<sup>-/-</sup> mouse model of atherosclerosis. [PDF]
Habelt B, Cuevas M, Dörr W.
europepmc +1 more source

