Results 11 to 20 of about 140,646 (292)

Cyclic guanosine monophosphate as a mediator of vasodilation. [PDF]

Journal of Clinical Investigation, 1986
Ferid Murad
openalex   +2 more sources

Acute effects of strength exercise with blood flow restriction on the arterial resistance index

Revista da Educação Física, 2020
The present study aimed to evaluate the acute behavior of the brachial artery resistance index (BARI) and popliteal artery resistance index (PARI) in response to low intensity strength exercises involving small (SMG) and large muscle groups (LMG ...
Sabrina Lencina Bonorino, Vanessa da Silva Corralo, Sedinei Lopes Copatti, Eduardo Simões da Matta, Alex Lazzari Dornelles, Clodoaldo Antônio de Sá   +5 more
doaj   +1 more source

Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction

Frontiers in Physiology, 2021
The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of the intestinal tract, as well as by bacterial enzymes in the ...
Tilman Sauerbruch, Martin Hennenberg, Jonel Trebicka, Ulrich Beuers   +3 more
doaj   +1 more source

Gastroprotective mechanism of modified lvdou gancao decoction on ethanol-induced gastric lesions in mice: Involvement of Nrf-2/HO-1/NF-κB signaling pathway

Frontiers in Pharmacology, 2022
Modified Lvdou Gancao decoction (MLG), a traditional Chinese medicine formula, has been put into clinical use to treat the diseases of the digestive system for a long run, showing great faculty in gastric protection and anti-inflammatory, whereas its ...
Lei Xie, Minyi Luo, Junlin Li, Wenguan Huang, Guangjun Tian, Xiuyun Chen, Ying Ai, Yan Zhang, Haolan He, Jinyang He   +9 more
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Selective Phosphodiesterase 1 Inhibitor BTTQ Reduces Blood Pressure in Spontaneously Hypertensive and Dahl Salt Sensitive Rats: Role of Peripheral Vasodilation

Frontiers in Physiology, 2020
Regulation of the peripheral vascular resistance via modulating the vessel diameter has been considered as a main determinant of the arterial blood pressure.
Asim B. Dey, Sherif Khedr, Sherif Khedr, James Bean, Leah L. Porras, Tamika D. Meredith, Francis S. Willard, Joseph V. Hass, Xin Zhou, Maia Terashvili, Cynthia D. Jesudason, Kevin M. Ruley, Michael R. Wiley, Mark Kowala, Simon J. Atkinson, Alexander Staruschenko, Alexander Staruschenko, Mark D. Rekhter   +17 more
doaj   +1 more source

Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease

Pulmonary Circulation, 2022
Pulmonary veno‐occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH) is a rare subtype of pulmonary hypertension with dismal prognosis.
Junichi Nakamura, Ichizo Tsujino, Hideki Shima, Toshitaka Nakaya, Ayako Sugimoto, Takahiro Sato, Taku Watanabe, Hiroshi Ohira, Masaru Suzuki, Satonori Tsuneta, Ryo Hisada, Masaru Kato, Satoshi Konno   +12 more
doaj   +1 more source

Safranal Induces Vasorelaxation by Inhibiting Ca²⁺ Influx and Na⁺/Ca²⁺ Exchanger in Isolated Rat Aortic Rings

Molecules, 2022
Introduction: Safranal, which endows saffron its unique aroma, causes vasodilatation and has a hypotensive effect in animal studies, but the mechanisms of these effects are unknown.
Noor Nadhim Al-Saigh, Shtaywy Abdalla
doaj   +1 more source

Comparative Study of Different H₂S Donors as Vasodilators and Attenuators of Superoxide-Induced Endothelial Damage

Antioxidants, 2023
In the last years, research proofs have confirmed that hydrogen sulfide (H2S) plays an important role in various physio-pathological processes, such as oxidation, inflammation, neurophysiology, and cardiovascular protection; in particular, the protective
Elisabetta Marini, Barbara Rolando, Federica Sodano, Federica Blua, Giulia Concina, Stefano Guglielmo, Loretta Lazzarato, Konstantin Chegaev   +7 more
doaj   +1 more source

Class effects of SGLT2 inhibitors in mouse cardiomyocytes and hearts: inhibition of Na+/H+ exchanger, lowering of cytosolic Na+ and vasodilation

Diabetologia, 2017
Aims/hypothesisSodium–glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) constitute a novel class of glucose-lowering (type 2) kidney-targeted agents. We recently reported that the SGLT2i empagliflozin (EMPA) reduced cardiac cytosolic Na+ ([Na+]c) and ...
L. Uthman, A. Baartscheer, B. Bleijlevens, C. Schumacher, J. Fiolet, A. Koeman, Milena Jancev, M. Hollmann, N. Weber, R. Coronel, C. Zuurbier   +10 more
semanticscholar   +1 more source

Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

Frontiers in Cardiovascular Medicine, 2022
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva, Christopher J. Hatch, Megan T. Chu, Trevor R. Cardinal   +3 more
doaj   +1 more source