Results 11 to 20 of about 101,746 (297)

Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease

Pulmonary Circulation, 2022
Pulmonary veno‐occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH) is a rare subtype of pulmonary hypertension with dismal prognosis.
Junichi Nakamura, Ichizo Tsujino, Hideki Shima, Toshitaka Nakaya, Ayako Sugimoto, Takahiro Sato, Taku Watanabe, Hiroshi Ohira, Masaru Suzuki, Satonori Tsuneta, Ryo Hisada, Masaru Kato, Satoshi Konno   +12 more
doaj   +1 more source

Safranal Induces Vasorelaxation by Inhibiting Ca²⁺ Influx and Na⁺/Ca²⁺ Exchanger in Isolated Rat Aortic Rings

Molecules, 2022
Introduction: Safranal, which endows saffron its unique aroma, causes vasodilatation and has a hypotensive effect in animal studies, but the mechanisms of these effects are unknown.
Noor Nadhim Al-Saigh, Shtaywy Abdalla
doaj   +1 more source

Comparative Study of Different H₂S Donors as Vasodilators and Attenuators of Superoxide-Induced Endothelial Damage

Antioxidants, 2023
In the last years, research proofs have confirmed that hydrogen sulfide (H2S) plays an important role in various physio-pathological processes, such as oxidation, inflammation, neurophysiology, and cardiovascular protection; in particular, the protective
Elisabetta Marini, Barbara Rolando, Federica Sodano, Federica Blua, Giulia Concina, Stefano Guglielmo, Loretta Lazzarato, Konstantin Chegaev   +7 more
doaj   +1 more source

Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal α-Adrenergic Signaling and a Transient Loss of Vascular Tone

Frontiers in Cardiovascular Medicine, 2022
Stimulating collateral arteriogenesis is an attractive therapeutic target for peripheral artery disease (PAD). However, the potency of arteriogenesis-stimulation in animal models has not been matched with efficacy in clinical trials.
Alexander Silva, Christopher J. Hatch, Megan T. Chu, Trevor R. Cardinal   +3 more
doaj   +1 more source

The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease

Frontiers in Molecular Neuroscience, 2023
IntroductionThe disintegrin and metalloproteinase 17 (ADAM17) exhibits α-secretase activity, whereby it can prevent the production of neurotoxic amyloid precursor protein-α (APP).
Yanna Tian, Katie Anne Fopiano, Vadym Buncha, Liwei Lang, Hayden A. Suggs, Rongrong Wang, R. Daniel Rudic, Jessica A. Filosa, Zsolt Bagi   +8 more
doaj   +1 more source

Direct-Acting Vasodilators [PDF]

The Journal of Clinical Hypertension, 2011
KEY POINTS AND PRACTICAL RECOMMENDATIONS: •  Hydralazine and minoxidil act by dilating resistance arterioles, thus reducing peripheral resistance, with no dilating effect on the venous side of the circulation. •  There is a baroreflex-mediated venoconstriction, resulting in an increase in venous return to the heart, along with a direct catecholamine ...
Alexander M. M. Shepherd, Jay N. Cohn, Gordon T. McInnes   +2 more
openaire   +3 more sources

ACONITE AS A VASODILATOR [PDF]

The American Journal of the Medical Sciences, 1915
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openaire   +2 more sources

Fast Isolation of Flavonoids from the Endemic Species Nolana ramosissima I.M. Johnst and Its Endothelium-Independent Relaxation Effect in Rat Aorta

Molecules, 2020
The infusion of the desertic plant Nolana ramosissima I.M. Johnst showed vascular smooth muscle relaxation in rat aorta and the presence of several phenolic compounds, which were detected by high resolution UHPLC-Orbitrap-HESI-MS.
Fredi Cifuentes, Javier Palacios, Jorge Bórquez, Adrián Paredes, Claudio Parra, Alejandra Bravo, Mario J. Simirgiotis   +6 more
doaj   +1 more source

Cerebral Vasodilators

Japanese Journal of Pharmacology, 1998
The vascular tone, vascular resistance and blood flow in the brain are regulated by neural and humoral factors in quite a different way from those of peripheral organs and tissues. In contrast to the dominant vasoconstrictor control in the periphery, the intracranial vascular tone is predominantly influenced by vasodilator mediators over ...
N, Toda, T, Okamura
openaire   +3 more sources

Cold induced vasodilation [PDF]

The Biomedical & Life Sciences Collection, 2008
Reactie op: Flouris, et al. Effect of body temperature on cold induced vasodilationa. Eur J Applied Phys 2008;104:491-499. De aurteurs hebben daar weer een reply op geschreven; Flouris AD, Cheung SS (2009) Authors’ response to H. Daanen’s ‘cold-induced vasodilation’ letter.
openaire   +2 more sources