Study of vasodilation processes
Journal of Education, Health and Sport, 2019 To date, the key role of endothelial dysfunction in the occurrence and progression of diabetes mellitus and diabetic retinopathy has been proven. The study was performed on white Wistar rats weighing 180-200 g.
Ya. V. Sirman, I. V. Savytskyi
doaj +3 more sources
OGG1 Preserves Endothelial-Dependent Vasodilation and Regulates the Frequency and Spatial Area of Endothelial Calcium Signals [PDF]
BiomoleculesEndothelial calcium dysregulation underlies impairments in endothelial-dependent vasodilation (EDV), contributing to vascular disease progression. Repletion of 8-oxoguanine DNA glycosylase (OGG1), an enzyme involved in base excision repair, has been ...
Takreem Aziz +4 more
doaj +2 more sources
The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]
Antioxidants and Redox Signaling, 2013 Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Alex Dyson +23 more
core +2 more sources
Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta [PDF]
Korean Journal of Anesthesiology, 2013 BackgroundIntravenous lipid emulsion has been used to treat systemic toxicity of local anesthetics. The goals of this in vitro study were to determine the ability of two lipid emulsions (Intralipid® and Lipofundin® MCT/LCT) to reverse toxic dose local ...
Seong-Ho Ok +7 more
doaj +2 more sources
Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. [PDF]
Journal of Clinical Investigation, 1994 The purpose of this study was to examine whether insulin's effect to vasodilate skeletal muscle vasculature is mediated by endothelium-derived nitric oxide (EDNO).
Helmut O. Steinberg +4 more
openalex +2 more sources
Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. [PDF]
Journal of Clinical Investigation, 1991 Hyperinsulinemia may contribute to hypertension by increasing sympathetic activity and vascular resistance. We sought to determine if insulin increases central sympathetic neural outflow and vascular resistance in humans.
Erling A. Anderson +4 more
openalex +2 more sources
Bile Acids, Liver Cirrhosis, and Extrahepatic Vascular Dysfunction
Frontiers in Physiology, 2021 The bile acid pool with its individual bile acids (BA) is modulated in the enterohepatic circulation by the liver as the primary site of synthesis, the motility of the gallbladder and of the intestinal tract, as well as by bacterial enzymes in the ...
Tilman Sauerbruch +3 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2023 IntroductionThe disintegrin and metalloproteinase 17 (ADAM17) exhibits α-secretase activity, whereby it can prevent the production of neurotoxic amyloid precursor protein-α (APP).
Yanna Tian +8 more
doaj +1 more source
Geriatrics, Gerontology and Aging, 2023 The objective of this review is to identify the acute effects of blood flow restriction (BFR) with vs without exercise on endothelial function in healthy individuals and the changes in endothelial function in young and older adults following different ...
Gustavo Gonçalves Cardozo +6 more
doaj +1 more source
Additive effect of non-alcoholic fatty liver disease on metabolic syndrome-related endothelial dysfunction in hypertensive patients [PDF]
, 2016 Metabolic syndrome (MS) is characterized by an increased risk of incident diabetes and cardiovascular (CV) events, identifying insulin resistance (IR) and endothelial dysfunction as key elements.
Caroleo, B +6 more
core +6 more sources