Results 61 to 70 of about 9,502 (211)
Biological Research, 2009 Hyptidendron canum (Pohl ex Benth.) Harley is a native tree of the Brazilian Savannah. The fish Oreochromis niloticus L. was used as an experimental model to determine the bioactivity of the crude ethanol extract as well as ethyl acetate, hexanic and ...
TATIANA S FIUZA +4 more
doaj
Impaired neurovascular coupling in the APPxPS1 mouse model of Alzheimerâs disease [PDF]
arXiv, 2019 The tight coupling between neuronal activity and the local increase of blood flow termed neurovascular coupling is essential for normal brain function. This mechanism of regulation is compromised in Alzheimer's Disease (AD). In order to determine whether a purely vascular dysfunction or a neuronal alteration of blood vessels diameter control could be ...
arxiv
Animal Models and Experimental Medicine, EarlyView.This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin +9 more
wiley +1 more source
CRISPR applications for Duchenne muscular dystrophy: From animal models to potential therapies
WIREs Mechanisms of Disease, Volume 15, Issue 1, January/February 2023., 2023 CRISPR‐Cas9 gene‐editing technology enables the rapid generation of animal models for Duchenne muscular dystrophy research and has potential to be developed as CRISPR therapy for the long lasting genetic correction of causal mutations. Abstract CRISPR gene‐editing technology creates precise and permanent modifications to DNA.
Yu C. J. Chey +4 more
wiley +1 more source
Vasodilatory effects of cinnamaldehyde and its mechanism of action in the rat aorta
Vascular Health and Risk Management, 2011 Yong-Liang Xue1, Hai-Xia Shi1, Ferid Murad1,2, Ka Bian1,21Murad Research Institute for Modernized Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China; 2E-Institute of Shanghai Universities ...
Bian K, Hai-xia Shi, Murad F, Xue Y
doaj
Fat‐Specific Protein 27 Regulation of Vascular Function in Human Obesity
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019 Background Pathophysiological mechanisms that connect obesity to cardiovascular disease are incompletely understood. FSP27 (Fat‐specific protein 27) is a lipid droplet‐associated protein that regulates lipolysis and insulin sensitivity in adipocytes.
Shakun Karki +11 more
doaj +1 more source
Sports, 2020 (-)-Epicatechin is a polyphenol previously shown to enhance vascular health. The purposes of the current studies were to determine the effect of acute (-)-epicatechin supplementation on local vasodilation in conjunction with resistance exercise (study 1)
Neil A. Schwarz +5 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The aim of this study was to improve the long‐term LL‐37 mouse model and compare the disease manifestations and pathophysiology of short‐term and long‐term LL‐37‐induced rosacea‐like models. The results show that the long‐term LL‐37 induced mouse model provides a practical animal model for further study of the pathological mechanism of severe rosacea ...
Yiling Wu +10 more
wiley +1 more source
Integration of an enhanced recovery after surgery program for patients undergoing pituitary surgery
World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 8, Issue 4, Page 330-338, December 2022., 2022 Abstract Evidence‐based enhanced recovery after surgery (ERAS) programs aim to improve patient outcomes and shorten hospital stays. The objective of this study is to describe the development, implementation, and evolution of an ERAS protocol to optimize the perioperative management for patients undergoing endoscopic skull base surgery for pituitary ...
Stephanie Flukes +9 more
wiley +1 more source
Arthritis &Rheumatology, EarlyView.Objective Systemic sclerosis (SSc) is a rare but severe autoimmune disease characterized by immune dysregulation, fibrosis, and vasculopathy. Although previous studies have highlighted the presence of functional autoantibodies targeting the angiotensin II receptor type 1 (AT1) and endothelin‐1 type A receptor (ETAR), leading to autoantibody‐mediated ...
Wieke M. van Oostveen +8 more
wiley +1 more source