Results 41 to 50 of about 1,544,203 (251)

The Pharmacology of Vasodilator Agents on Vascular Muscle [PDF]

open access: yes
The aims of this study were: i) to evaluate rat vascular muscle preparations as model systems for predicting or assessing vasodilator efficacy on human vasculature; ii) to use rat vascular muscle to classify vasodilators by their spectrum of activity and
Louttit, James B.
core   +1 more source

Diagnostic Agreement and Threshold Correspondence Between Resting Full‐Cycle Ratio and Nicorandil‐Based Fractional Flow Reserve in Intermediate Coronary Stenosis: A Prospective Single‐Center Registry

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background RFR has shown good aggregate agreement with FFR, including in prior Asian cohorts using intracoronary nicorandil. Where RFR‐FFR disagreement is concentrated relative to the FFR 0.80 decision boundary, and how the two binary thresholds correspond, remain incompletely characterized. Methods In a prospective single‐center registry, 300
Yonghoon Shin   +8 more
wiley   +1 more source

Pharmacological exploitation of vasodilator in the management of hypertension

open access: yes, 2020
Exploitation of vasodilators is effective against hypertension in emergency case and long term hypertension. The choice of the drug should always be considered from patient’s status, since different vasodilators have different mechanism of action and can
Okubo, Kaishu
core  

High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity

open access: yesKidney & Blood Pressure Research, 2015
Background/Aims. High salt (HS) intake may elevate blood pressure (BP), also in animals without genetic salt sensitivity. The development of salt-dependent hypertension could be mediated by endogenous vasoactive agents; here we examined the role of ...
A. Walkowska   +7 more
doaj   +1 more source

Cardiovascular complications following chronic treatment with cocaine and testosterone in adolescent rats. [PDF]

open access: yesPLoS ONE, 2014
Concomitant use of anabolic androgenic steroids and cocaine has increased in the last years. However, the effects of chronic exposure to these substances during adolescence on cardiovascular function are unknown.
Sheila A Engi   +5 more
doaj   +1 more source

The effects of sodium–glucose cotransporter 2 inhibitors on the ‘forgotten’ right ventricle

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1045-1058, April 2025.
Abstract With the progress in diagnosis, treatment and imaging techniques, there is a growing recognition that impaired right ventricular (RV) function profoundly affects the prognosis of patients with heart failure (HF), irrespective of their left ventricular ejection fraction (LVEF).
Liangzhen Qu, Xueting Duan, Han Chen
wiley   +1 more source

Comparação do efeito da nimodipina e da papaverina como vasodilatadores sobre o fluxo na artéria torácica interna esquerda Comparison of the effects on the flow in the left internal thoracic artery using nimodipine and papaverine as vasodilators

open access: yesBrazilian Journal of Cardiovascular Surgery, 2006
OBJETIVO: O objetivo do presente estudo é comparar o fluxo da artéria torácica interna esquerda sob o efeito local farmacológico por embebição e o efeito intraluminal de bloqueador do canal de cálcio com um grupo controle com papaverina.
Edhino Santos Junior   +3 more
doaj   +1 more source

Cilostazol in patients with heart failure and preserved ejection fraction—The CLIP‐HFpEF trial

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1437-1446, April 2025.
• Cilostazol is an oral PDE‐3 inhibitor that may have advantageous effects in heart failure with preserved ejection fraction (HFpEF). • Cilostazol significantly improved short‐term heart failure‐related health status scores (KCCQ‐12) and NT‐proBNP levels when compared to placebo.
Norman Aiad   +9 more
wiley   +1 more source

Milrinone in Enterovirus 71 Brain Stem Encephalitis

open access: yesFrontiers in Pharmacology, 2016
Enterovirus 71 (EV71) was implicated in a widespread outbreak of hand-foot-and-mouth disease (HFMD) across the Asia Pacific area since 1997 and has also been reported sporadically in patients with brain stem encephalitis. Neurogenic shock with pulmonary
SHIH-MIN eWANG   +2 more
doaj   +1 more source

Prognostic value of resting coronary sinus flow determined by phase-contrast cine cardiovascular magnetic resonance in patients with known or suspected coronary artery disease

open access: yesJournal of Cardiovascular Magnetic Resonance, 2021
Background Phase-contrast cine cardiovascular magnetic resonance (CMR) of the coronary sinus has emerged as a non-invasive method to measure coronary sinus blood flow (CSBF) and coronary flow reserve (CFR).
Shingo Kato   +8 more
doaj   +1 more source

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