Results 81 to 90 of about 53,380 (285)
Pharmacological Treatment of Interstitial Lung Diseases: A Novel Landscape for Inhaled Agents
PharmaceuticsInterstitial lung diseases (ILDs) encompass a heterogeneous group of over 200 disorders that require individualized treatment. Antifibrotic agents, such as nintedanib and pirfenidone, have remarkably revolutionized the treatment landscape of patients ...
Vito D’Agnano +8 more
doaj +1 more source
Drugs in R&D, 2019 Background Pulmonary arterial hypertension is a hemodynamic disorder. Signs and symptoms are generally difficult to recognize because they are non-specific. The current treatment for pulmonary arterial hypertension offers no cure or prevention; therefore,
Alan David Kaye +4 more
doaj +1 more source
The Role of rescue therapies in the treatment of severe ARDS [PDF]
, 2018 ARDS is characterized by a non-cardiogenic pulmonary edema with bilateral chest radiograph opacities and hypoxemia refractory to oxygen therapy. It is a common cause of admission to the ICU due to hypoxemic respiratory failure requiring mechanical ...
Alessandri, F, Pugliese, F, Ranieri, M.
core +1 more source
European Journal of Heart Failure, EarlyView.Summary of the change in left ventricular systolic and diastolic parameters from baseline to 12 months in patients with permanent atrial fibrillation (AF) and a left ventricular ejection fraction (LVEF) ≥50%. P‐values indicate the significance of the adjusted mean difference of the parameters at 12 months between the beta‐blocker and digoxin arm. E/e′,
Karina V. Bunting +10 more
wiley +1 more source
Stable coronary syndromes: pathophysiology, diagnostic advances and therapeutic need [PDF]
, 2018 The diagnostic management of patients with angina pectoris typically centres on the detection of obstructive epicardial CAD, which aligns with evidence-based treatment options that include medical therapy and myocardial revascularisation.
Berry, Colin +2 more
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Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats [PDF]
, 2017 This protocol describes the use of in vitro television microscopy to evaluate vascular function in isolated cerebral resistance arteries (and other vessels), and describes techniques for evaluating tissue perfusion using Laser Doppler Flowmetry (LDF) and
Allen, L. Adrienne +6 more
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Natriuretic peptides and cardiovascular damage in the metabolic syndrome. Molecular mechanisms and clinical implications [PDF]
, 2010 Natriuretic peptides are endogenous antagonists of vasoconstrictor and salt- and water-retaining systems in the body's defence against blood pressure elevation and plasma volume expansion, through direct vasodilator, diuretic and natriuretic properties ...
ALONZO, ALESSANDRO +4 more
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Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, EarlyView.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Effects of acute consumption of fruit and vegetable puree-based drinks on vasodilation and oxidative status [PDF]
, 2012 Epidemiological studies indicate that diets rich in fruits and vegetables (F&V) are protective against cardiovascular diseases (CVD). Pureed \&V products retain many beneficial components, including flavonoids, carotenoids, vitamin C and dietary fibres ...
George, Trevor +4 more
core +1 more source
Small Science, EarlyView.Cancer and neurodegeneration share interconnected nanosized molecular pathways. Novel nanobiomedicine approaches promise targeted biomarkers and therapies. Atomic force microscopy (AFM) is invaluable to characterize nanosized biomolecular processes beyond imaging.
Carlos Marcuello +5 more
wiley +1 more source