Results 11 to 20 of about 2,655 (189)

Vasoplegia: A Review

open access: yesMethodist DeBakey Cardiovascular Journal, 2023
Vasoplegia is a condition characterized by persistent low systemic vascular resistance despite a normal or high cardiac index, resulting in profound and uncontrolled vasodilation. Vasoplegia may occur due to various conditions, including cardiac failure,
Iqbal Ratnani   +3 more
doaj   +3 more sources

Vasoplegia: Mechanism and Management Following Cardiopulmonary Bypass

open access: diamondEurasian Journal of Medicine, 2022
Vasoplegia is defined by hypotension and low systemic vascular resistance despite the normal or elevated cardiac index, a complication frequently following cardiac surgery, carrying high morbidity and mortality rate. Vasoplegia is related with a profound systemic inflammatory response and is mainly mediated by cellular hyperpolarization, a relative ...
Rizal Muhammad   +3 more
doaj   +4 more sources

Vasoplegia Following Complex Spine Surgery: Incidence and Risk

open access: goldGlobal Spine Journal, 2022
Study design Retrospective cohort study Objectives Vasoplegia is a life-threatening form of distributive or vasodilatory shock that is characterized by reduced systemic vascular resistance with resultant hypotension and normal to elevated cardiac output affecting morbidity and mortality. Vasoplegia in the context of Spine Surgery has not been described
Basem Ishak   +5 more
openalex   +3 more sources

Commentary: Vasoplegia—Be prepared! [PDF]

open access: bronzeThe Journal of Thoracic and Cardiovascular Surgery, 2019
Carl L. Backer
openalex   +3 more sources

Endothelial cell responses in sepsis are attenuated by targeting truncated procalcitonin [PDF]

open access: yesNature Communications
Sepsis is associated with hypotension, vascular leakage, vasoplegia and microvascular dysfunction. Therefore, the endothelium is a target for sepsis therapies.
Laura Brabenec   +14 more
doaj   +2 more sources

Vasoplegia treatments: the past, the present, and the future [PDF]

open access: yesCritical Care, 2018
Vasoplegia is a ubiquitous phenomenon in all advanced shock states, including septic, cardiogenic, hemorrhagic, and anaphylactic shock. Its pathophysiology is complex, involving various mechanisms in vascular smooth muscle cells such as G protein-coupled
Bruno Levy   +5 more
doaj   +3 more sources

The Durability of Intravenous Hydroxocobalamin in Vasoplegia [PDF]

open access: diamondCureus, 2023
Objectives Refractory distributive shock (vasoplegia) has been treated with intravenous (IV) hydroxocobalamin (B12), but its use is poorly characterized. The objective of this study was to quantify the duration of hemodynamic improvement after B12 administration. Materials and methods This was a retrospective chart review of adult patients who received
Madeline Blaha   +2 more
openalex   +3 more sources

Neuroendocrine predictors of vasoplegia after cardiopulmonary bypass [PDF]

open access: hybridJournal of Endocrinological Investigation, 2020
Abstract Purpose Vasoplegia often complicates on-pump cardiac surgery. Systemic inflammatory response induced by extracorporeal circulation represents the major determinant, but adrenal insufficiency and postoperative vasopressin deficiency may have a role. Pathophysiological meaning of perioperative changes in endocrine
Daniela Pasero   +14 more
openalex   +4 more sources

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