Results 1 to 10 of about 164 (88)

Hydroxocobalamin in Refractory Septic Shock: A Retrospective Case Series

open access: yesCritical Care Explorations, 2021
Objectives:. Refractory septic shock is associated with high morbidity and mortality. Hydroxocobalamin is used to treat postoperative vasoplegia; however, data supporting its use in the setting of refractory septic shock is limited and restricted to case
Alicia J. Sacco, PharmD, BCCCP   +3 more
doaj   +1 more source

Exploring the Accessibility by Using the Hydroxycobalamin Preparations of High Concentration in Treating Methylmalonic Acidemia

open access: yes罕见病研究, 2023
Methylmalonic acidemia(MMA) is one of the common diseases in hereditary organic acid metabolism disorder. The disorder is mainly treated by using vitamin B12 which comes in various forms.The use of the methylcobalamin and adenosylcobalamin in China ...
LI Ruohan   +3 more
doaj   +1 more source

Various injury patterns due to combustion (typical but unfamiliar to physicians and easy to miss) in Korea: a case report [PDF]

open access: yesJournal of Trauma and Injury, 2023
Patients transported from fire sites may exhibit various injury patterns. Major trauma, skin burn, inhalation burn, and carbon monoxide poisoning are typical injuries. However, most physicians may be unfamiliar that cyanide poisoning can frequently occur
Hyung Il Kim
doaj   +1 more source

Potent Antiviral Activity of Vitamin B12 against Severe Acute Respiratory Syndrome Coronavirus 2, Middle East Respiratory Syndrome Coronavirus, and Human Coronavirus 229E

open access: yesMicroorganisms, 2023
Repurposing vitamins as antiviral supporting agents is a rapid approach used to control emerging viral infections. Although there is considerable evidence supporting the use of vitamin supplementation in viral infections, including severe acute ...
Yassmin Moatasim   +12 more
doaj   +1 more source

A Sensitive Voltammetric Approach Employing a Bare Boron-Doped Diamond Electrode as a Sensor for the Determination of Hydroxocobalamin

open access: yesEngineering Proceedings, 2023
The voltammetric behavior of hydroxocobalamin (OH-CBL) was firstly studied by employing a bare boron-doped diamond electrode as a working electrode. It was found that OH-CBL provided four anodic signals on BDDE in acidic supporting electrolytes and one ...
Lenka Janíková   +3 more
doaj   +1 more source

Homicide with intramuscular cyanide injection: a case report

open access: yesToxicology Communications, 2022
Cyanide poisoning most commonly occurs from smoke inhalation, less commonly by oral ingestion for suicide or homicide. There are rare cases of intravenous or subcutaneous parenteral cyanide.
Natasha Tobarran   +4 more
doaj   +1 more source

High‐dose hydroxocobalamin achieves biochemical correction and improvement of neuropsychiatric deficits in adults with late onset cobalamin C deficiency

open access: yesJIMD Reports, 2020
Cobalamin C (cblC) deficiency is the most common inborn error of intracellular cobalamin metabolism caused by pathogenic variant(s) in MMACHC and manifests with methylmalonic acidemia, hyperhomocysteinemia, and hypomethioninemia with a variable age of ...
Tomoyasu Higashimoto   +9 more
doaj   +1 more source

Pediatric Cyanide Poisoning After Ingestion of Apricot Seeds

open access: yesJournal of Pediatric Emergency and Intensive Care Medicine, 2020
Cyanide is one of the strongest and lethal poisons. Cyanide leads to tissue hypoxia and lactic acid accumulation. Hydroxocobalamin is a safe, fast and effective antidote that could be used, especially in children.
Yüksel Bıcılıoğlu   +3 more
doaj   +1 more source

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

open access: yesAntioxidants, 2021
TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes.
Yu-Mi Jeon   +8 more
doaj   +1 more source

Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study

open access: yesCritical Care, 2019
Background The use of hydroxocobalamin has long been advocated for treating suspected cyanide poisoning after smoke inhalation. Intravenous hydroxocobalamin has however been shown to cause oxalate nephropathy in a single-center study.
François Dépret   +30 more
doaj   +1 more source

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