Results 41 to 50 of about 164 (88)

Cyanide intoxication by apricot kernels: A case report and literature review

Emergency Care Journal, 2019
Acute cyanide intoxication is a serious healthcare problem due to its potentially life threatening and fatal toxic effects. Ingestion of cyanide containing foods is an important source of cyanide poisoning and apricot kernels contain significant amounts ...
Faruk Ekinci, Dincer Yildizdas, Alper Ates, Naime Gökay   +3 more
doaj   +1 more source

Guidelines for Essential Trauma Care: Second Edition (2026)

World Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock, Timothy C. Hardcastle, Christine Gaarder, Amit Gupta, Adam Gyedu, Manjul Joshipura, Elmin Steyn, on behalf of the Essential Trauma Care revision author group, Valencia Adjei, Roger Alcock, Vanda Amado, Michael Boampong, Sanjeev Booi, Petra Brysiewicz, Corazon Cabanilla‐Manuntag, Cristiane de Alencar Domingues, Ghada Elhadari, Ranjith Nanda Ellawala, Sarnai Erdene, Ama Akoma Essuman, Jorge Esteban Foianini, Filippo Gatti, Armando Garcia Guererra, Greg Hynes, Adil Haider, Sandy Ingless, Balavenkata Jagannathan, Helen Jowett, Knut Magne Kolstadbråten, Sonja Krofak, Aireen Patricia Madrid, Tina Tomić Mahečić, Claude Martin, Daniel Ntogwrachu, Bisola Onajin‐Obembe, Nhobojit Roy, Andres Rubiano, Niisoja Mensah Torto, Ben Wachira, Meg Walmsley, Torben Wisborg, Elma Wong   +41 more
wiley   +1 more source

Genetic testing is necessary for correct diagnosis and treatment in patients with isolated methylmalonic aciduria: a case report

BMC Pediatrics, 2021
Background Isolated methylmalonic aciduria can be caused by pathogenic mutations in the gene for methylmalonyl-CoA mutase or in the genes encoding enzymes involved in the intracellular metabolism of cobalamin.
Katarína Brennerová, Martina Škopková, Mária Ostrožlíková, Jana Šaligová, Juraj Staník, Vladimír Bzdúch, Daniela Gašperíková   +6 more
doaj   +1 more source

Metabolic Enzyme MeHNL11 Regulates MeCAS1b Transcription for Cyanide Reutilization in Response to Nitrate Deficiency in Cassava

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4121-4135, June 2026.
ABSTRACT Cassava (Manihot esculenta Crantz) exhibits exceptional tolerance to infertile soils and contains abundant cyanogenic glucosides (CGs). Previous research has indicated that CGs can serve as a significant reservoir of organic nitrogen in plants.
Weitao Mai, Ruxue Bao, Xiaocheng Liu, Mengtao Li, Jinling Zhao, Huaifang Zhang, Yuan Yao, Haiyan Wang, Wenquan Wang, Changying Zeng, Xin Chen   +10 more
wiley   +1 more source

An In Vitro Model of Gastric Inflammation and Treatment with Cobalamin

International Journal of Inflammation, 2017
Pernicious anaemia (PA) is an autoimmune condition where antibodies target intrinsic factor and parietal cells, reducing the patient’s ability to absorb cobalamin promoting atrophic gastritis.
T. R. Elliott, A. L. Guildford
doaj   +1 more source

Skin Hyperpigmentation: An Under‐Recognized Dermatological Clue to Vitamin B12 Deficiency

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Hyperpigmentation over the dorsal aspect of both hands, prominently involving the knuckles. ABSTRACT Cutaneous hyperpigmentation, an overlooked manifestation, can be an early sign of vitamin B12 deficiency. This case highlights symmetric pigmentation on the dorsum of hands and palms in a long‐term vegetarian.
Mahesh Mathur, Sumit Paudel, Sambidha Karki, Sandhya Regmi, Shilpa Maharjan, Nabita Bhattarai   +5 more
wiley   +1 more source

Valproate therapy exacerbating intermediate phenotype of methylmalonic aciduria

Journal of Pediatric Neurosciences, 2015
A, 11-year-old male, with delayed milestones after the age of 6 months with recurrent myoclonus and generalized tonic-clonic seizures had clinical worsening after institution of valproate, was detected to have elevated serum lactate level and marked ...
Aditya Murgai, Aviraj Deshmukh, Vinod Puri, Neera Chaudhry, Seema Kapoor   +4 more
doaj   +1 more source

A novel TCN2 mutation with unusual clinical manifestations of hemolytic crisis and unexplained metabolic acidosis: expanding the genotype and phenotype of transcobalamin II deficiency

BMC Pediatrics, 2022
Background Transcobalamin deficiency is a rare inborn metabolic disorder, characterized by pancytopenia, megaloblastic anemia, failure to thrive, diarrhea, and psychomotor retardation.
Pongpak Pongphitcha, Nongnuch Sirachainan, Arthaporn Khongkraparn, Thipwimol Tim-Aroon, Duantida Songdej, Duangrurdee Wattanasirichaigoon   +5 more
doaj   +1 more source

Assessment of blood cobalt levels and safety of long-term hydroxocobalamin therapy in patients with cblC defect

Frontiers in Nutrition
BackgroundHydroxocobalamin (OHCbl), the most effective form of vitamin B12 containing cobalt (Co) as its core component, is the mainstay therapy for cobalamin C (cblC) defect, yet long-term Co exposure and safety signals remain incompletely characterized.
Lili Hao, Yi Ding, Yuxin Deng, Ting Chen, Xia Zhan, Feng Xu, Haijuan Zhi, Kaichuang Zhang, Yi Yang, Ruifang Wang, Yuning Sun, Lianshu Han   +11 more
doaj   +1 more source

Exploratory Laparotomy After Routine Cardiac Surgery: Results From 17,000 Patients

World Journal of Surgery, Volume 50, Issue 5, Page 1221-1227, May 2026.
Exploratory laparotomy is rare after open‐heart surgery, and it was performed for gastrointestinal complications that occurred in the context of other severe postoperative complications. Several factors were associated with the need for exlap, including increasing age, pre‐existing renal and vascular disease, and pre‐ and post‐operative shock. ABSTRACT
Megan Turner, James A. Brown, Pyongsoo Yoon, Michelle Yoon, Zeyu Liu, Zihan Feng, Ryan Rivosecchi, Holt Murray, Jianhui Zhu, Floyd Thoma, Derek Serna‐Gallegos, David Kaczorowski, Johannes Bonatti, Danny Chu, Irsa Hasan, Takuya Ogami, Ibrahim Sultan   +16 more
wiley   +1 more source