Results 21 to 30 of about 164 (88)

Role of Non-catecholamines Vasopressors in the Management of Vasoplegic Syndrome after Cardiopulmonary Bypass: A Scoping Review

Annals of Cardiac Anaesthesia
Vasoplegic syndrome is a life-threatening condition characterized by uncontrolled peripheral vasodilation, leading to profound arterial hypotension. Treatments include catecholamines, vasopressin, methylene blue (MB), hydroxocobalamin, angiotensin II ...
Amarjeet Kumar, Athira Jayan, Poonam Kumari, Kunal Singh, Aakanksha Hiremath   +4 more
doaj   +1 more source

Essential Oral Single Nutritional Therapy Products for Inherited Metabolic Diseases: Evidence and Consensus Assessment Using a Modified Delphi Method

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nutritional therapy is critical in managing inherited metabolic diseases (IMDs), and includes specialized diets and single nutritional therapy products (sNTPs) such as vitamins, cofactors, and amino acids. Many sNTPs function as medicines, but are regulated as food (e.g., food supplements), which can limit access, reimbursement, and consistent
Nina N. Stolwijk, Bart M. F. Penninx, Annet M. Bosch, Mirjam Langeveld, Gajja S. Salomons, Carla E. M. Hollak, Essential Nutritional Therapy Products for IMDs Consensus Group, Dorothea Möslinger, Saskia Wortmann, David Cassiman, Pavel Ješina, Jiri Zeman, Allan M. Lund, François Feillet, Nazi Tabatadze, Sarah C. Grünert, Anke Schumann, Ute Spiekerkoetter, Ulrike Mütze, Thomas Opladen, Anastasia Skouma, Ina Knerr, Serena Gasperini, Vincenza Gragnaniello, Mariarosa (Marina) Anna Beatrice Melone, Francesca Nardecchia, Alessandro La Rosa, Birutė Tumienė, Margreet Wagenmakers, Terry Derks, Camilla Tøndel, Beata Kieć‐Wilk, Urh Groselj, Amaya Bélanger‐Quintana, Javier De las Heras, Mireia del Toro Riera, Eva Venegas Moreno, Matthias Gautschi, Johannes Häberle, Elaine Murphy   +39 more
wiley   +1 more source

A Case of Hydroxocobalamin-Induced False Blood Leak Alarm on Dialysis Machine

Journal of Investigative Medicine High Impact Case Reports, 2019
Hemodialysis machines are equipped with a blood leak detector/alarm to prevent loss of blood following rupture of semipermeable membrane; the blood leak alarms could also be triggered by sensor malfunction or presence of air bubbles in the system ...
Praveen Datar MBBS, Jasdeep Singh Sidhu MBBS, Jeevanjot Virk MBBS, Osama Mukhtar MBBS, Frances Schmidt MD, Vijay Gayam MBBS   +5 more
doaj   +1 more source

Effect of hydroxocobalamin on nimodipine-induced refractory vasoplegia in a patient with liver cirrhosis: a case report [PDF]

Journal of Neurocritical Care
Background We report a case of severe vasoplegia that was unresponsive to triple vasopressor therapy but showed marked hemodynamic improvement following intravenous hydroxocobalamin administration in a patient with underlying cirrhosis.
Sally You
doaj   +1 more source

Hypocortisolaemia with gastrointestinal haemorrhage in a young cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐month‐old, female, spayed domestic shorthair presented with a 1‐week history of lethargy and anorexia. On admission, the cat had severe hypoglycaemia, and hypovolaemic and distributive shock were suspected. Mucosal defects identified by ultrasonography were suggestive of gastrointestinal ulceration.
Victoria J. Skinner, Bronwyn Zimmerman, Ivayla D. Yozova   +2 more
wiley   +1 more source

Hydroxocobalamin for the treatment of vasoplegia after lung transplantation: A case series

JHLT Open
Background: The use of hydroxocobalamin following lung transplantation has not been previously reported. We present a series of 3 cases where hydroxocobalamin was used to treat postoperative vasoplegia.
Anh Nguyen, MD, PhD, Rima Bouajram, PharmD, Marek Brzezinski, MD, Sahand Hassanipour, David Gordon, Binh Trinh, MD, Tobias Deuse, MD, Aida Venado, MD, Steve Hays, MD, Jonathan Singer, MD, Jasleen Kukreja, MD, MPH   +10 more
doaj   +1 more source

Protocol Compliance Guiding Angiotensin II Use in Post Cardiovascular Surgery Vasoplegia

Critical Care Explorations, 2022
OBJECTIVES:. Catecholamines and vasopressin are commonly used in patients with post cardiovascular surgery vasoplegia (PCSV). Multimodal therapy, including methylene blue (MB), hydroxocobalamin, and angiotensin II (Ang II), may improve outcomes in ...
Caitlin C. ten Lohuis, MSN, ACNP-BC, Sarah C. Burke, MD, Cooper J. Jannuzzo, MS, Nicholas A. Barker, PharmD, Edward P. Chen, MD, Laurence W. Busse, MD, MBA, FCCM   +5 more
doaj   +1 more source

A Retrospective Descriptive Analysis of Consultations Provided by the National Poisons Centre Relating to Medicines on the Aotearoa New Zealand Antidote Stocking Guideline, 2020–2025

Emergency Medicine Australasia, Volume 38, Issue 5, October 2026.
ABSTRACT Objective Many antidotes are relatively rare‐use, indication‐specific medicines with a variable evidence base. In Aotearoa New Zealand, there are no national statistics available on their use. This study aimed to characterize the numbers of cases and advice provided by the Aotearoa New Zealand National Poisons Centre (NZNPC) on the use of true
Eeva‐Katri Kumpula, William Boroughf
wiley   +1 more source

Cobalamin‐Dependent O‐Demethylation of Polymethoxyflavones by Enzymes Isolated From the Human Gut Microorganism Blautia producta MRG‐PMF1

Advanced Synthesis &Catalysis, Volume 368, Issue 16, 18 August 2026.
O‐demethylation of aryl methyl ethers is an invaluable transformation, playing a critical role in ecological circulation by degrading abundant lignin‐derived compounds and other natural products. Chemical O‐demethylation requires harsh reaction conditions; thus, the need for biocatalytic solutions is of high interest.
Niels Krabbe Johnsen, Mykola Franchuk, Freja Elisabeth Wind Rasmussen, Zheng Guo, Jaehong Han, Bekir Engin Eser   +5 more
wiley   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, Volume 13, Issue 7, Page 1518-1523, July 2026.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source