Results 121 to 130 of about 25,819 (299)

Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior

open access: green, 2012
Jennifer L. Garrison   +5 more
openalex   +2 more sources

Degradation Pathways of Therapeutic Peptides in Aqueous Solutions and Strategies to Improve Stability [PDF]

open access: yes, 2015
A number of hormones, enzymes, antitumor agents, antibiotics and neurotransmitters are peptides. Nowadays, peptides are used as therapeutic agents against diverse disease areas such as neurological, endocrinological and hematological disorders ...
Avanti, Christina
core  

Compartmentalisation in cAMP signalling: A phase separation perspective

open access: yesBritish Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Reviewer #1 (Public Review): β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

open access: gold, 2023
Daly Carole   +5 more
openalex   +1 more source

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang   +2 more
wiley   +1 more source

Liquid–Liquid Phase Separation in Major Hallmarks of Cancer

open access: yesCell Proliferation, EarlyView.
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie   +10 more
wiley   +1 more source

Cardiovascular biomarkers and preeclampsia: A narrative review

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Preeclampsia (PE) is a complex pregnancy disorder linked to cardiovascular disease (CVD) through shared risk factors and epidemiological associations. Cardiovascular biomarkers are valuable for predicting, diagnosing and assessing PE, as well as estimating future CVD risk. This review explores current cardiovascular biomarkers used in clinical practice
Johana Ullmo   +8 more
wiley   +1 more source

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