Results 61 to 70 of about 2,428 (235)
British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Clinical Endocrinology, EarlyView.ABSTRACT Objective Hyponatraemia is a common electrolyte disorder often driven by excess arginine vasopressin (AVP). Copeptin is a stable surrogate marker co‐secreted with AVP. It is unclear whether treatment of hyponatraemia with tolvaptan, an AVP‐V2 receptor antagonist, impacts copeptin.
Annabelle M. Warren +4 more
wiley +1 more source
Comment on "The Vasopressin Loading for Refractory septic shock (VALOR) study: a prospective observational study". [PDF]
Crit Care, 2023 Kotani Y, Hayashi Y.
europepmc +1 more source
Attention Based Optimization for 3D Shape Registration
Computer Graphics Forum, EarlyView.Abstract Transformers are sequence‐to‐sequence architectures originally designed to handle structurally rigid and order‐sensitive data, such as text and images. At their core, they exploit the attention mechanism, which is permutation‐equivariant and relies on computing token‐to‐token relationships.
A. Riva, L. Olearo, S. Melzi
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Endogenous hypercortisolism (EHC) is an underrecognised and clinically significant contributor to hypertension, particularly resistant hypertension. Once viewed as a rare entity, EHC is now understood as a spectrum of cortisol excess associated with adverse cardiometabolic outcomes and target‐organ damage.
Omar Al Dhaybi, Deepak L. Bhatt
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aims The association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and the development of bowel obstruction/ileus remains unclear, and evidence for specific bowel obstruction/ileus subtypes remains limited. We examined the association between GLP‐1RA use and the incidence of bowel obstruction/ileus subtypes across different ...
Yuichiro Matsuo +3 more
wiley +1 more source
A chemo‐enzymatic colorimetric cascade for detecting ethylene glycol contamination
The FEBS Journal, EarlyView.A chemo‐enzymatic cascade is developed for ethylene glycol (EG) detection. EG is oxidized by GoADH with C1‐mediated cofactor recycling to produce glycolaldehyde (GAL). GAL subsequently reacts with purpald to generate a detectable purple chromophore.
Tawatchai Singphongam +6 more
wiley +1 more source
Haemophilia, EarlyView.ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini +4 more
wiley +1 more source
Hepatology Research, EarlyView.ABSTRACT Aim Genetic polymorphisms of alcohol‐metabolizing enzymes influence drinking behavior and susceptibility to alcohol‐related liver disease (ALD). This study aimed to clarify the distribution of ALDH2 and ADH1B genotypes in liver transplant recipients with ALD, and to explore associations with post‐transplant drinking behavior using a recipient ...
Noriyo Yamashiki +3 more
wiley +1 more source