Results 71 to 80 of about 2,482 (262)

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira   +5 more
wiley   +1 more source

Synthesis and biological activities of arginine-vasopressin analogues with reactive groups

open access: yes, 1980
Beschrieben werden Synthese und Eigenschaften von Derivaten des Arginin-Vasopressins, in welchen Tyr2 oder Phe3 durch p-Azido-L-phenylalanin [Phe(pN3)] oderp-(Brom-acetylamino)-L-phenylalanin[Phe(/7NHCOCH2Br)] ersetzt sind.
Thierauch, K.   +5 more
core   +1 more source

Dexmedetomidine infusions improve cardiovascular and renal function in anaesthetised, experimentally endotoxaemic horses

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Dexmedetomidine infusions are beneficial in anaesthetised endotoxaemic horses when administered concurrent to endotoxin, but post‐conditioning effects are unknown. Objectives To evaluate whether a dexmedetomidine infusion is beneficial in horses administered Escherichia coli O55:B5 lipopolysaccharides (LPS) endotoxin prior to ...
Sera Lee   +4 more
wiley   +1 more source

Genetic and Molecular Basis of Processing Traits and Genetic Improvement Progress in Major Fruit Crops

open access: yesFuture Postharvest and Food, EarlyView.
Processing quality in fruit crops is governed by complex genetic networks controlling texture, sweetness, color, browning, aroma, and nutritional quality. Advances in genomics, genomic selection, and genome editing enable the development of processing‐oriented cultivars with improved industrial performance, reduced postharvest losses, and enhanced ...
M. Ranjani   +2 more
wiley   +1 more source

Vasopressin and Memory Consolidation

open access: yes, 1976
Publisher Summary The hypothalamic-neurohypophyseal system possibly makes use of (a) the general circulation for peripheral effects of posterior pituitary hormones; (b) the portal vessel system for the regulation of anterior pituitary function; and (c) the cerebrospinal fluid for CNS activities.
Gispen, W.H.   +4 more
openaire   +4 more sources

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

open access: yesiNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin   +10 more
wiley   +1 more source

Adverse Effects of Unsaturated Organic Compounds on Kinetic States During Locomotion Uncovered by Comprehensive Analysis of Behavioral Toxicities in C. elegans

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Organisms in human living spaces are surrounded by a variety of engineered substances. These chemical compounds have unexpected effects on the environment and human health. In particular, workers in industries face the risk of a health hazard caused by high‐dose or long‐term exposure to chemicals in the workplace.
Masahiro Tomioka
wiley   +1 more source

Gene regulation of vasopressin and vasopressin receptors in cancer

open access: yesExperimental Physiology, 2000
It is proposed that neuropeptide production by tumours is an important part of a special process of oncogenic transformation rather than a pre‐existing condition of progenitor cells; this concept is called Selective Tumour gene Expression of Peptides essential for Survival (STEPS).
openaire   +2 more sources

Inositol lipid-mediated signalling in response to endothelin and ATP in the mammalian testis

open access: yes, 1995
The testis is a complex organ in which local control is achieved by signalling between its constituent cells. Herein we describe the responses of cultured rat testicular cells and a mouse Sertoli cell-line to stimulation by endothelin and ATP, and ...
Hughes, Phillip J.   +4 more
core   +1 more source

Reward processing in children with affective dysregulation

open access: yesJCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner   +11 more
wiley   +1 more source

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