Results 211 to 220 of about 33,095 (252)

Vitamin D and Uterine Fibroids: Insights into Pathophysiology and Therapeutic Potential.

open access: yesEndocr Rev
Ciebiera M   +9 more
europepmc   +1 more source

Paget’s disease—A VDR coactivator disease? [PDF]

open access: yesThe Journal of Steroid Biochemistry and Molecular Biology, 2004
Paget's disease is the most exaggerated example of bone remodeling with increased osteoclastic bone resorption followed by excessive bone formation. One of the earliest findings in our studies of Paget's disease is that pagetic osteoclast (OCL) precursors are hyper-responsive to 1,25-(OH)(2)D(3) and form OCL at concentrations of 1,25-(OH)(2)D(3) that ...
Kurihara, Noriyoshi   +4 more
openaire   +3 more sources

Cybersecurity risk assessment of VDR

open access: yesJournal of Navigation, 2023
AbstractThe voyage data recorder (VDR) is a data recording system that aims to provide all navigational, positional, communicational, sensor, control and command information for data-driven investigation of accidents onboard ships. Due to the increasing dependence on interconnected networks, cybersecurity threats are one of the most severe issues and ...
Ömer Söner   +3 more
openaire   +4 more sources

Cdx-2 polymorphism in the vitamin D receptor gene (VDR) marks VDR expression in monocyte/macrophages through VDR promoter methylation

Immunogenetics, 2018
Caudal-type homeobox protein 2 (CDX-2) is an intestine-specific transcription factor (TF), with a polymorphic binding site (Cdx-2, rs11568820, A/G) in the vitamin D receptor gene (VDR). The molecular mechanism underlying Cdx-2 association with conditions like osteoporosis, which depends on intestinal VDR expression and calcium absorption, is believed ...
Vanessa Meyer, Liza Bornman
exaly   +3 more sources

VDR - the next generation [PDF]

open access: yes, 2008
The European Maritime Data Management (EMDM) project faces the challenge of safe and secure European transport development with the study and development of new applications, functionalities and proposals for Voyage Data Recorders (VDRs) and Electronic Logbooks (ELBs).
Austin, S.   +3 more
openaire   +2 more sources

In vivo function of VDR in gene expression-VDR knock-out mice

The Journal of Steroid Biochemistry and Molecular Biology, 1999
Vitamin D exerts many biological actions through nuclear vitamin D receptor (VDR)-mediated gene expression. The transactivation function of VDR is activated by binding 1alpha,25-dihydroxyvitamin D3[1alpha,25(OH)2D3], an active form of vitamin D. Conversion from 25(OH)D3 is finely regulated in kidney by 25(OH)D3 1alpha-hydroxylase[25(OH)D 1alpha ...
S, Kato   +5 more
openaire   +2 more sources

Functional role of VDR in the activation of p27Kip1 by the VDR/Sp1 complex

Journal of Cellular Biochemistry, 2006
AbstractOur previous study demonstrate that vitamin D3 induces the binding of vitamin D3 receptor (VDR) to Sp1 transcription factor and stimulates p27Kip1 expression via the Sp1 consensus sequences in the promoter. Both VDR and Sp1 are transcriptional activators, it is unclear which protein functions as the transcription component of the VDR/Sp1 ...
Hsuen-Tsen, Cheng   +4 more
openaire   +2 more sources

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