Results 221 to 230 of about 182,452 (358)

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

Current Distribution of Selected Vector-borne Diseases in Domestic Dogs From Bucharest, Romania. [PDF]

Vet Med Sci
Sandu I, Cristea CD, Ionică AM, Deak G.
europepmc   +1 more source

Vector-borne diseases and their control [PDF]

Parasitology Research, 2008
Jutta, Klasen, Birgit, Habedank
openaire   +2 more sources

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

Registered Nurses' Knowledge, Attitudes, and Practices Toward Climate-Sensitive Vector-Borne Diseases: Findings From a Cross-Sectional Survey. [PDF]

Public Health Nurs
Vandenberg SY, Oosterbroek T, Chircop A, Kellett P.   +3 more
europepmc   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Challenges and Strategies for the Development and Implementation of Climate-Informed Early Warning Systems for Vector-Borne Diseases: A Systematic Review. [PDF]

Trop Med Int Health
Pham CT, Nguyen HT, Le HHTC, Tran NQL, Do KQ, Bui V, Phung H, Phung D, Chu C.   +8 more
europepmc   +1 more source

Impact of Nano-Insecticides in Vector Borne Diseases

R. Anbalagan, S. K. Farhat, Jayalakshmi Krishnan   +2 more
openalex   +2 more sources

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Multicriteria Decision Analysis as a Tool for Assessing Vector-Borne Diseases Risk: The Case of Crimean-Congo Hemorrhagic Fever in Türkiye. [PDF]

Microorganisms
Milano A, Juache A, Houben S, Dente MG, Robbiati C, Declich S, Danielyan R, Ozkul A, Karayel-Hacıoglu I, Drakulović MB, Hendrickx G, Marsboom C.   +11 more
europepmc   +1 more source