Results 191 to 200 of about 68,761 (259)

MoVe: an integrated tool to explore the relationship between human mobility and vector-borne disease. [PDF]

Sci Rep
Sa-Ngamuang C, Yin MS, Barkowsky T, Lawpoolsri S, Bicout DJ, Haddawy P.   +5 more
europepmc   +1 more source

Construction of a clickable probe‐based protein chip platform for discovering covalent mIDH1 inhibitors from natural medicinal extracts

iMeta, EarlyView.
In this study, we develop a flexible Ccc‐Chip (protein microarray + bioorthogonal click chemistry) for high‐throughput screening of natural covalent active molecules from medicinal plant extracts, identifying flavokawain C from Piper methysticum Forst as a novel covalent mIDH1 inhibitor.
Zhao Cui, Jiameng Li, Caifeng Li, Mo Sun, Wei Liu, Xuxia Cao, Shiwen Deng, Junxian Cao, Hongjun Yang, Peng Chen   +9 more
wiley   +1 more source

Climate-driven infectious disease risks: a global scoping review of epidemiological patterns, methodological gaps, and policy imperatives. [PDF]

BMC Infect Dis
Çeleğen İ, Sarıöz A.
europepmc   +1 more source

Respiratory Syncytial Virus Under the Lens of Structure: From Prefusion Stabilization to Next‐Generation Immunotherapies

iNew Medicine, EarlyView.
This illustration integrates key concepts covered in the review, including high‐risk populations, viral structure, host entry factors, the replication cycle, and licensed antibody‐based prevention strategies. ABSTRACT Respiratory syncytial virus (RSV) is a negative‐sense RNA virus belonging to the genus Orthopneumovirus within the family Pneumoviridae.
Zekai Cheng, Qianqian Wang, Jiachen Zhang, Sandra Chiu   +3 more
wiley   +1 more source

The epidemiological characteristics of notifiable infectious diseases in a Yunnan hospital, China, 2014-2023. [PDF]

BMC Public Health
Zhang Y, Zhang Y, Zhou F, Chen S, Dai D, Li C, Duan Y, Liu M.   +7 more
europepmc   +1 more source

Intratumoral bacteria engineered for tumor therapy

Interdisciplinary Medicine, EarlyView.
This article comprehensively reviews engineered intratumoral bacteria used in tumor therapy. The concept development, characteristics, and engineering methods of intratumoral bacteria are summarized. The mechanisms and the translational significance by which engineered intratumoral bacteria interfere with tumor progression are discussed and highlighted.
Huajie Zhang, Zelin Chen, Zeyu Yao, Sishi Luo, Cheng Luo, Rui Yang, Hao Fu, Songyin Huang   +7 more
wiley   +1 more source

Distribution of Aedes aegypti and Aedes albopictus, and the current situation of dengue fever and chikungunya in Iran and neighboring countries: a review study. [PDF]

PLoS Negl Trop Dis
Shoushtari M, Bakhshi H, Salehi-Vaziri M, Zaim M, Enayati A, Pouriayevali MH, Moradi G, Sedaghat MM, Mirolyaei A, Mostafavi E, Bagheri Amiri F.   +10 more
europepmc   +1 more source

First Report of Homozygous COL7A1 c.5756delG Mutation Causing Recessive Dystrophic Epidermolysis Bullosa in a Non‐Consanguineous Japanese Family

JEADV Clinical Practice, EarlyView.
ABSTRACT Severe recessive dystrophic epidermolysis bullosa (RDEB) is usually caused by biallelic loss‐of‐function mutations in COL7A1. While the c.5756delG variant has been previously reported in heterozygous form, its clinical impact in homozygosity has not been described.
Nozomi Kohama, Sayaka Yamaguchi, Teruki Yanagi, Yumi Akamine, Kimiko Nonaka, Daisuke Utsumi, Kenzo Takahashi   +6 more
wiley   +1 more source

A Review of the Changing Global Impact of Arthropod-Borne Virus Diseases and Recent Initiatives from the World Health Organization. [PDF]

Med Sci Monit
Parums DV.
europepmc   +1 more source

Unrestricted kinematic alignment on the sagittal plane: Posterior tibial slope and combined flexion do not have boundaries to respect in terms of short‐term clinical outcomes and safety

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose Personalized alignment in total knee arthroplasty (TKA) is gaining traction as a surgical philosophy. True personalization, however, must encompass not only the coronal plane but also the sagittal and axial planes. This study evaluates influence of the Tibial Slope (PTS) and combined flexion (CF) on outcomes in TKA performed using ...
Edoardo Franceschetti, Pietro Gregori, Stefano Campi, Marco Spatuzzi, Giancarlo Giurazza, Andrea Tanzilli, Biagio Zampogna, Matteo Formica, Umile Giuseppe Longo, Rocco Papalia   +9 more
wiley   +1 more source