Prevalence, diagnostic evaluation, and disease associations of vector-borne pathogens in domestic dogs across Namibia: a multi-modal approach. [PDF]
de Villiers L+13 more
europepmc +1 more source
Qualitative and quantitative analysis of vector-borne infection through fractional framework
Rashid Jan+4 more
openalex +2 more sources
Estimation ofR0from the initial phase of an outbreak of a vector-borne infection
Eduardo Massad+3 more
openalex +1 more source
We designed and synthesized novel mannose‐6‐phosphate (M6P) derivatives to enhance their binding affinity for the CI‐M6P/IGF2 receptor, which plays a key role in lysosomal targeting. Using a fluorescence polarization assay, we evaluated di‐, tri‐, and penta‐M6P peptides and modified M6P analogs.
Lucie Mrázková+11 more
wiley +1 more source
Seroprevalence study for selected zoonotic vector-borne pathogens in sheep from endemic areas of Croatia. [PDF]
Barbic L+9 more
europepmc +1 more source
Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi+7 more
wiley +1 more source
Harnessing Viral Proteases for Cellular and Molecular Engineering
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui+2 more
wiley +1 more source
An exploration of current and future vector-borne disease threats and opportunities for change. [PDF]
Hiscox A+10 more
europepmc +1 more source
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang+3 more
wiley +1 more source