Results 221 to 230 of about 132,009 (295)

Compound heterozygous SLC12A5 variants expand the molecular and functional spectrum of KCC2‐developmental and epileptic encephalopathy

Epilepsia, EarlyView.
Overview of the multimodal experimental approach integrating clinical, genetic, in silico, and in vitro investigations. Clinical: Representative EEG recording setup and ictal traces from affected patients. Genetic: Pedigrees for Families A and B highlighting the inheritance of the four identified SLC12A5 variants (A1, A2, B1, B2).
Mira Hamze, Robyn Whitney, Dorothée Ville, Nathalie Villeneuve, Anna‐Maria Hartmann, Lisa Becker, Jens Hausmann, Jinwei Zhang, Cathy Brier, Lucie I. Pisella, Perrine Friedel, Audrey Labalme, Eudeline Alix, Nicolas Chatron, Damien Sanlaville, Sylvie Gory‐Fauré, Eric Denarier, Christophe Porcher, Gaetan Lesca, Igor Medina   +19 more
wiley   +1 more source

A systematic review investigating emerging trends between Extreme Weather Events (EWEs) and infectious disease outbreaks in South Africa. [PDF]

Front Public Health
Dickinson N, Spencer LH, Miller C, Nadesan-Reddy N, Viriri S, Shakir MZ, Gebreslasie M, Ndzi D, Mahomed OH, Naidoo S, Lynch M, Henriquez FL.   +11 more
europepmc   +1 more source

Skin models for studying vector-borne kinetoplastid infections

Current Opinion in Microbiology
Laura Hauf, Markus Engstler
openaire   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

Epilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang, Emilio Perucca, Samuel F. Berkovic, Piero Perucca   +3 more
wiley   +1 more source

Safeguarding future generations: a One Health perspective on children, climate change, and infectious threats. [PDF]

Front Public Health
Masetti M, Lato F, Menoni M, Esposito S.
europepmc   +1 more source

The Global Patent Landscape of Mushroom‐Derived Functional Foods: Current Status, Future Perspectives, and Artificial Intelligence–Driven Exploration

Food Safety and Health, EarlyView.
The global patent landscape of mushroom‐derived functional food was widely analyzed, and AI‐integrated approaches realizing cost‐effective and reliable exploration of functional foods derived from mushrooms were explored. ABSTRACT Global health concerns and the increasing demand for nourishment have collectively driven the rising demand for functional ...
Xihong Zhao, Linhuizi Xiang, Dongmei Liu, Shoucheng Qin, Yue Chen, Xueyan Sun   +5 more
wiley   +1 more source

Interaction between tick and host microbiotas: a four-step waltz. [PDF]

Parasit Vectors
Baquer F, Grillon A.
europepmc   +1 more source

Climate change and the rising threat of vector-borne diseases in the Andes. [PDF]

One Health
Ortiz-Prado E, Vasconez-Gonzalez J, Pazmiño-Almeida JC, Serrano-Núñez MR, Acosta-Muñoz E, Sánchez-Bustamante JS, Salazar-Santoliva C, Bastidas AP, Altamirano-Castillo JA, Villacis-Pauta SV, Izquierdo-Condoy JS.   +10 more
europepmc   +1 more source

Generation of Allogeneic CAR‐T Circumvents Functional Deficits in Patient‐Derived Autologous Product for Glioblastoma

International Journal of Cancer, EarlyView.
Clinical trials of chimeric antigen receptor T‐cell (CAR‐T) therapies in glioblastoma have shown limited clinical benefits. Whether this may be explained by the basal quality of CAR‐T products, which are currently generated using patient, autologous T‐cells, has been little explored.
Sabra K. Salim, Muhammad Vaseem Shaikh, Jeffrey Wei, William T. Maich, Alisha Anand, Oliver Y. Tang, Minomi K. Subapanditha, Zahra Alizada, Yujin Suk, Manoj Singh, Kui Zhai, Aapti Khanna, Benjamin Brakel, Vassil Dimitrov, Zoya Tabunshchyk, Katie Chan, Kevin R. Brown, Parvez Vora, Donald M. O'Rourke, Zev A. Binder, Chitra Venugopal, Jason Moffat, Sheila K. Singh   +22 more
wiley   +1 more source

Single nucleotide polymorphisms are typical for tick-borne encephalitis and West Nile viruses during triple natural mixed infections in Blyth's reed warbler (Acrocephalus dumetorum). [PDF]

Vavilovskii Zhurnal Genet Selektsii
Ponomareva EP, Ternovoi VA, Protopopova EV, Tupota NL, Loktev VB.   +4 more
europepmc   +1 more source