Results 241 to 250 of about 164,296 (306)

The global burden of climate-sensitive diseases in Brazil: the national and subnational estimates and analysis, 1990-2017. [PDF]

Popul Health Metr
de Sousa TCM, Barcellos C, Barreto ML.
europepmc   +1 more source

Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond

Macromolecular Bioscience, EarlyView.
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley   +1 more source

One Health, many approaches: integrated vector management strategies support One Health goals. [PDF]

Front Insect Sci
Tiffin HS, Gordon JR, Poh KC.
europepmc   +1 more source

Reduced JAG1 Expression Through miR‐200 Overexpression or Crispr‐Cas Mediated Knockout Impairs TNBC Growth and Metastasis

Molecular Carcinogenesis, EarlyView.
ABSTRACT Studies from our lab demonstrated that increasing miR‐200 expression in human triple negative breast cancer (TNBC) reduced tumor growth and metastasis In Vivo. In this study, we found that overexpression of miR‐200s in TNBC cells significantly reduced the expression of JAG1.
Megan Vaz, Katrina L. Watson, Roger A. Moorehead   +2 more
wiley   +1 more source

High Diversity and Low Coinfections of Pathogens in Ticks from Ruminants in Pakistan. [PDF]

Microorganisms
Jamil L, Li C, Wang Y, Jamil J, Tian W, Zhao D, Shen S, Sun Y, Zhao L, Cao W.   +9 more
europepmc   +1 more source

Early‐Onset Movement Disorder Syndrome Caused by Biallelic Variants in PDE1B Encoding Phosphodiesterase 1B

Movement Disorders, EarlyView.
Abstract Background Breakdown of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in basal ganglia cells through hydrolysis of diesteric bonds, primarily by PDE10A and PDE1B, is essential for normal human movement. While biallelic loss‐of‐function variants in PDE10A are known to cause hyperkinetic movement disorders, the ...
Tomer Poleg, Noam Hadar, Eyal Kristal, Nicola Y. Roberts, Vadim Dolgin, Ilana Aminov, Amit Safran, Nadav Agam, Matan Jean, Ofek Freund, Eamonn G. Sheridan, James A. Poulter, Michelle L. Thompson, Yusra Algoos, Salma Al‐Qahtani, Lama AlAbdi, Sateesh Maddirevula, Verity Hartill, Henry Houlden, Reza Maroofian, Amit Nahum, Ohad S. Birk   +21 more
wiley   +1 more source

Pathogenicity and virulence of Powassan virus. [PDF]

Virulence
Kaur M, Adam M, Mladinich MC.
europepmc   +1 more source

Weathering the storms of climate change: Preparing persons with disabilities and the physiatrists who provide their care for extreme hurricanes

PM&R, EarlyView.
Abstract Climate‐driven disasters have disproportionate and often devastating consequences on individuals with disabilities. Warming ocean and air temperatures are fueling more extreme tropical cyclones, further endangering those living in at‐risk regions.
Mollie Andreae, James M. Shultz, J. Marshall Shepherd, Zelde Espinel, Lauren T. Shapiro   +4 more
wiley   +1 more source

Bluetongue's New Frontier-Are Dogs at Risk? [PDF]

Vet Sci
Payan-Carreira R, Simões M.
europepmc   +1 more source

Structural and Functional Characterization of the 28 kDa Structured Core of BmSA1, the Major Surface Antigen of Babesia Microti

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Babesiosis is a tick‐borne disease that poses a significant threat to animal health worldwide. In addition, climate change and the risk of human‐to‐human transmission through blood transfusion have made babesiosis an emerging disease in humans.
Assia Mouhand, Joana Pissarra, Philippe Barthe, Christian Roumestand, Stéphane Delbecq   +4 more
wiley   +1 more source