Results 31 to 40 of about 68,761 (259)

Innate and Adaptive Immune Genes Associated with MERS-CoV Infection in Dromedaries

open access: yesCells, 2021
The recent SARS-CoV-2 pandemic has refocused attention to the betacoronaviruses, only eight years after the emergence of another zoonotic betacoronavirus, the Middle East respiratory syndrome coronavirus (MERS-CoV).
Sara Lado   +12 more
doaj   +1 more source

Modeling preferential attraction to infected hosts in vector-borne diseases

open access: yesFrontiers in Public Health, 2023
Vector-borne infectious diseases cause more than 700,000 deaths a year and represent an increasing threat to public health worldwide. Strategies to mitigate the spread of vector-borne diseases can benefit from a thorough understanding of all mechanisms that contribute to viral propagation in human.
Ishwor Thapa, Dario Ghersi
openaire   +3 more sources

Neurocognitive deficits after botulism: a clinical case series study

open access: yesFrontiers in Neurology
PurposeThis case study examined long-term cognitive deficits after botulism. Only a very limited number of studies on post-acute cognitive impairment after botulism exist, and data are incomplete.MethodA semi-structured interview on long-term cognitive ...
Laura Rosenqvist   +2 more
doaj   +1 more source

Arthropod-Borne Pathogens in Wild Canids

open access: yesVeterinary Sciences, 2023
Wild canids, as well as other wild animal species, are largely exposed to bites by ticks and other hematophagous vectors where the features favoring their presence and spread are found in wooded and semi-wooded areas.
Valentina Virginia Ebani   +2 more
doaj   +1 more source

Emerging roles of non-coding RNAs in vector-borne infections [PDF]

open access: yesJournal of Cell Science, 2020
ABSTRACT Non-coding RNAs (ncRNAs) are nucleotide sequences that are known to assume regulatory roles previously thought to be reserved for proteins. Their functions include the regulation of protein activity and localization and the organization of subcellular structures. Sequencing studies have now identified thousands of ncRNAs encoded
Chaima Bensaoud   +4 more
openaire   +2 more sources

Usutu virus, Austria and Hungary, 2010–2016Usutu virus, Austria and Hungary, 2010–2016

open access: yesEmerging Microbes and Infections, 2017
Usutu virus (USUV, Flaviviridae) was first reported in Europe in Austria in 2001, where it caused wild bird (mainly blackbird) mortality until 2005. Since 2006 no further USUV cases were diagnosed in the country.
Tamás Bakonyi   +5 more
doaj   +1 more source

An update on the mosquito fauna and mosquito-borne diseases distribution in Cameroon

open access: yesParasites & Vectors, 2021
The expansion of mosquito-borne diseases such as dengue, yellow fever, and chikungunya in the past 15 years has ignited the need for active surveillance of common and neglected mosquito-borne infectious diseases.
Roland Bamou   +9 more
doaj   +1 more source

Current Status of Vector-Borne Diseases in Croatia: Challenges and Future Prospects

open access: yesLife, 2023
Different vector-borne pathogens are present or have (re-)emerged in Croatia. Flaviviruses tick-borne encephalitis (TBEV), West Nile (WNV), and Usutu (USUV) are widely distributed in continental regions, while Toscana virus (TOSV) and sandfly fever ...
Tatjana Vilibic-Cavlek   +9 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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